(Q37950950)

25 August 2017

Human pluripotent stem cells for disease modelling and drug screening (English)

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25 August 2017

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3

Marc Peschanski

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25 August 2017

4

Cécile Martinat

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25 August 2017

2

Morgane Gauthier

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25 August 2017

Yves Maury

1

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PubMed ID

22038777

25 August 2017

language of work or name

English

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publication date

28 October 2011

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25 August 2017

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25 August 2017

34

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25 August 2017

1

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25 August 2017

61-71

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Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells

25 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Disease-specific induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Induced pluripotent stem cells from individuals with recessive dystrophic epidermolysis bullosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Modelling schizophrenia using human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Directed differentiation of human-induced pluripotent stem cells generates active motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Generation of insulin-secreting islet-like clusters from human skin fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Induction and isolation of vascular cells from human induced pluripotent stem cells--brief report

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Differential modulation by nicotine of substantia nigra versus ventral tegmental area dopamine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Differential expression of the homeobox gene Pitx3 in midbrain dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Epigenetic modifications in pluripotent and differentiated cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Investigating monogenic and complex diseases with pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

DNA methylation dynamics in human induced pluripotent stem cells over time

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201100071

Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Copy number variation and selection during reprogramming to pluripotency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Somatic coding mutations in human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Clone- and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader-Willi syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader-Willi syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Expression of human BRCA1 variants in mouse ES cells allows functional analysis of BRCA1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Identification and selection of cardiomyocytes during human embryonic stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

High-efficiency siRNA-based gene knockdown in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

A ROCK inhibitor permits survival of dissociated human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Efficient and stable Sendai virus-mediated gene transfer into primate embryonic stem cells with pluripotency preserved.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Promotion of direct reprogramming by transformation-deficient Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Human induced pluripotent stem cells free of vector and transgene sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Induced pluripotent stem cells generated without viral integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Reprogramming of murine and human somatic cells using a single polycistronic vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

The use of induced pluripotent stem cells in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Generation of induced pluripotent stem cells using recombinant proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Diverse small-molecule modulators of SMN expression found by high-throughput compound screening: early leads towards a therapeutic for spinal muscular atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

A randomized sequential trial of creatine in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

From skin cells to hepatocytes: advances in application of iPS cell technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Combination of functional cardiomyocytes derived from human stem cells and a highly-efficient microelectrode array system: an ideal hybrid model assay for drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

New approaches in the differentiation of human embryonic stem cells and induced pluripotent stem cells toward hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

The controlled generation of functional basal forebrain cholinergic neurons from human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

A small molecule primes embryonic stem cells for differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

High-throughput screening in embryonic stem cell-derived neurons identifies potentiators of alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate-type glutamate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Conversion of mouse and human fibroblasts into functional spinal motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

High-efficiency derivation of human embryonic stem cell lines following pre-implantation genetic diagnosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Derivation, culture, and characterization of VUB hESC lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Derivation of human embryonic stem cell lines from embryos obtained after IVF and after PGD for monogenic disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Studying early lethality of 45,XO (Turner's syndrome) embryos using human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Mutant human embryonic stem cells reveal neurite and synapse formation defects in type 1 myotonic dystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Generation of pluripotent stem cells from patients with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Complete genetic correction of ips cells from Duchenne muscular dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Generation of induced pluripotent stem cell lines from Friedreich ataxia patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Induced pluripotent stem cells from a spinal muscular atrophy patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Patient-specific induced pluripotent stem-cell models for long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Modelling the long QT syndrome with induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100071

21 January 2018

Identifiers

DOI

10.1002/BIES.201100071

1 reference

25 August 2017

1 reference

PubMed ID

22038777