(Q37957800)

25 August 2017

title

Cryo-electron microscopy of ribosomal complexes in cotranslational folding, targeting, and translocation (English)

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cryogenic electron microscopy

25 August 2017

main subject

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author

Guy Schoehn

series ordinal

2

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Christiane Berger-Schaffitzel

25 August 2017

series ordinal

3

object named as

Christiane Schaffitzel

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Kèvin Knoops

object named as

Kèvin Knoops

series ordinal

1

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publication date

17 November 2011

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Wiley interdisciplinary reviews. RNA

25 August 2017

published in

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25 August 2017

volume

3

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25 August 2017

issue

3

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25 August 2017

page(s)

429-441

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A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome

25 August 2017

cites work

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What recent ribosome structures have revealed about the mechanism of translation

21 January 2018

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A 9 A resolution X-ray crystallographic map of the large ribosomal subunit

21 January 2018

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Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

21 January 2018

1 reference

GTPase activation of elongation factor EF-Tu by the ribosome during decoding

21 January 2018

1 reference

Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution

21 January 2018

1 reference

Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy

21 January 2018

1 reference

The structural basis of ribosome activity in peptide bond synthesis

21 January 2018

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Folding zones inside the ribosomal exit tunnel

21 January 2018

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Regulatory nascent peptides in the ribosomal tunnel

21 January 2018

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Structures of the bacterial ribosome at 3.5 A resolution

21 January 2018

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Three-dimensional structures of translating ribosomes by Cryo-EM.

21 January 2018

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Structure of the E. coli protein-conducting channel bound to a translating ribosome

21 January 2018

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Structural insight into nascent polypeptide chain-mediated translational stalling.

21 January 2018

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alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel

21 January 2018

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SecM-stalled ribosomes adopt an altered geometry at the peptidyl transferase center

21 January 2018

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Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

21 January 2018

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Nascent membrane and secretory proteins differ in FRET-detected folding far inside the ribosome and in their exposure to ribosomal proteins.

21 January 2018

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Tertiary interactions within the ribosomal exit tunnel

21 January 2018

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The ribosomal exit tunnel functions as a discriminating gate

21 January 2018

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Signal sequence-independent membrane targeting of ribosomes containing short nascent peptides within the exit tunnel

21 January 2018

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L23 protein functions as a chaperone docking site on the ribosome

21 January 2018

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The signal recognition particle binds to protein L23 at the peptide exit of the Escherichia coli ribosome

21 January 2018

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YidC and Oxa1 form dimeric insertion pores on the translating ribosome

21 January 2018

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Trigger factor in complex with the ribosome forms a molecular cradle for nascent proteins.

21 January 2018

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Molecular mechanism and structure of Trigger Factor bound to the translating ribosome

21 January 2018

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Trigger factor forms a protective shield for nascent polypeptides at the ribosome.

21 January 2018

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Real-time observation of trigger factor function on translating ribosomes.

21 January 2018

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Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on the Escherichia coli ribosome

21 January 2018

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Trigger factor retards protein export in Escherichia coli.

21 January 2018

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Trigger factor binds to ribosome-signal-recognition particle (SRP) complexes and is excluded by binding of the SRP receptor

21 January 2018

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Following the signal sequence from ribosomal tunnel exit to signal recognition particle

21 January 2018

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Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor

21 January 2018

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The Crystal Structure of the Signal Recognition Particle in Complex with Its Receptor

21 January 2018

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Structure of the E. coli signal recognition particle bound to a translating ribosome.

21 January 2018

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The signal recognition particle

21 January 2018

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Structural insights into the signal recognition particle

21 January 2018

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FtsY, the bacterial signal-recognition particle receptor, interacts functionally and physically with the SecYEG translocon

21 January 2018

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Substrate twinning activates the signal recognition particle and its receptor

21 January 2018

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Heterodimeric GTPase Core of the SRP Targeting Complex

21 January 2018

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Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication

21 January 2018

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Recognition of a signal peptide by the signal recognition particle

21 January 2018

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Structural basis of signal-sequence recognition by the signal recognition particle

21 January 2018

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Multiple conformational switches in a GTPase complex control co-translational protein targeting

21 January 2018

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Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor

21 January 2018

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Important role of the tetraloop region of 4.5S RNA in SRP binding to its receptor FtsY.

21 January 2018

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SRP RNA provides the physiologically essential GTPase activation function in cotranslational protein targeting

21 January 2018

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Transient tether between the SRP RNA and SRP receptor ensures efficient cargo delivery during cotranslational protein targeting

21 January 2018

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Synergistic actions between the SRP RNA and translating ribosome allow efficient delivery of the correct cargos during cotranslational protein targeting

21 January 2018

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Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting

21 January 2018

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Architecture of the protein-conducting channel associated with the translating 80S ribosome.

21 January 2018

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Structure of the signal recognition particle interacting with the elongation-arrested ribosome.

21 January 2018

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Signal recognition particle receptor exposes the ribosomal translocon binding site.

21 January 2018

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Structure, function and evolution of the signal recognition particle

21 January 2018

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X-ray structure of a protein-conducting channel

21 January 2018

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Investigating the SecY plug movement at the SecYEG translocation channel.

21 January 2018

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Signal sequence recognition in posttranslational protein transport across the yeast ER membrane.

21 January 2018

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Single Copies of Sec61 and TRAP Associate with a Nontranslating Mammalian Ribosome

21 January 2018

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Cryo-EM structure of the ribosome–SecYE complex in the membrane environment

21 January 2018

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The organization of engaged and quiescent translocons in the endoplasmic reticulum of mammalian cells

21 January 2018

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Protein translocation is mediated by oligomers of the SecY complex with one SecY copy forming the channel.

21 January 2018

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Three-dimensional structure of the bacterial protein-translocation complex SecYEG

21 January 2018

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The oligomeric state and arrangement of the active bacterial translocon

21 January 2018

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Three dimensional reconstructions of spherical viruses by fourier synthesis from electron micrographs

21 January 2018

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Identification of macromolecular complexes in cryoelectron tomograms of phantom cells

21 January 2018

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Structure of hibernating ribosomes studied by cryoelectron tomography in vitro and in situ

21 January 2018

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The native 3D organization of bacterial polysomes

21 January 2018

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Mapping 70S ribosomes in intact cells by cryoelectron tomography and pattern recognition.

21 January 2018

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The three-dimensional organization of polyribosomes in intact human cells

21 January 2018

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Cryo-electron microscopy of vitreous sections

21 January 2018

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Cutting artefacts on ultrathin cryosections of biological bulk specimens.

21 January 2018

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Exploring vitreous cryo-section-induced compression at the macromolecular level using electron cryo-tomography; 80S yeast ribosomes appear unaffected

21 January 2018

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Architecture of the Ribosome–Channel Complex Derived from Native Membranes

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/WRNA.119

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25 August 2017

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