(Q37959926)

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Optochemical genetics

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 August 2017

Optochemical genetics (English)

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Europe PubMed Central

PubMed publication ID

25 August 2017

author name string

Timm Fehrentz

1

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

Matthias Schönberger

2

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Europe PubMed Central

PubMed publication ID

25 August 2017

Dirk Trauner

3

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Europe PubMed Central

PubMed publication ID

25 August 2017

language of work or name

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publication date

23 November 2011

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Europe PubMed Central

PubMed publication ID

25 August 2017

Angewandte Chemie International Edition

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50

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Europe PubMed Central

PubMed publication ID

25 August 2017

51

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

12156-12182

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

The impact of molecular biology on neuroscience

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Optical switches for remote and noninvasive control of cell signaling.

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New photochemical tools for controlling neuronal activity.

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The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

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X-ray structure of a voltage-dependent K+ channel

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Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

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Refined structure of the nicotinic acetylcholine receptor at 4A resolution

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X-ray structure of a prokaryotic pentameric ligand-gated ion channel

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Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

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Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement

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Molecular and cellular approaches for diversifying and extending optogenetics

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Ultrafast optogenetic control.

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Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

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High-performance genetically targetable optical neural silencing by light-driven proton pumps

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Optical deconstruction of parkinsonian neural circuitry

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Optogenetic control of cardiac function

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Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor.

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Tuning photochromic ion channel blockers

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How does voltage open an ion channel?

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Voltage-gated potassium channels as therapeutic targets

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Crystal structure and mechanism of a calcium-gated potassium channel

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Crystal structure of a Kir3.1-prokaryotic Kir channel chimera

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Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution

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Atomic structure of a Na+- and K+-conducting channel

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Biophysical and molecular mechanisms of Shaker potassium channel inactivation

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Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB.

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Structural basis for the coupling between activation and inactivation gates in K(+) channels

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Structural mechanism of C-type inactivation in K(+) channels

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Modulation of C-type inactivation by K+ at the potassium channel selectivity filter

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Potassium channels in T lymphocytes: toxins to therapeutic immunosuppressants.

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Modeling the structure of agitoxin in complex with the Shaker K+ channel: a computational approach based on experimental distance restraints extracted from thermodynamic mutant cycles

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Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons

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Structural basis of TEA blockade in a model potassium channel

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Light-induced depolarization of neurons using a modified Shaker K(+) channel and a molecular photoswitch.

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21 January 2018

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21 January 2018

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21 January 2018

NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

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21 January 2018

Pharmacology of ionotropic glutamate receptors: A structural perspective

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21 January 2018

Allosteric control of an ionotropic glutamate receptor with an optical switch.

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21 January 2018

Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid

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Remote control of neuronal activity with a light-gated glutamate receptor

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21 January 2018

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An early Cambrian craniate-like chordate

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21 January 2018

Optogenetic dissection of a behavioural module in the vertebrate spinal cord

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21 January 2018

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21 January 2018

Evolutionary history of the ligand-gated ion-channel superfamily of receptors

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21 January 2018

GABAC receptors

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21 January 2018

Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics

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21 January 2018

Subunit composition, distribution and function of GABA(A) receptor subtypes

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21 January 2018

Deciphering the structural framework of glycine receptor anchoring by gephyrin

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21 January 2018

Nicotinic receptors at the amino acid level

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21 January 2018

Emerging structure of the nicotinic acetylcholine receptors

1 reference

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21 January 2018

Neuronal nicotinic receptors in the human brain

1 reference

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21 January 2018

Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy

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21 January 2018

Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors.

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21 January 2018

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

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21 January 2018

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

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21 January 2018

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

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21 January 2018

A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors

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21 January 2018

Photochromic Activators of the Acetylcholine Receptor

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21 January 2018

Activation of acetylcholine receptor channels by covalently bound agonists in cultured rat myoballs

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21 January 2018

A covalently bound photoisomerizable agonist: comparison with reversibly bound agonists at Electrophorus electroplaques.

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21 January 2018

The crystal structure of a voltage-gated sodium channel

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21 January 2018

The Venus flytrap of periplasmic binding proteins: an ancient protein module present in multiple drug receptors

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21 January 2018

Glutamate receptor-like genes form Ca2+ channels in pollen tubes and are regulated by pistil D-serine

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21 January 2018

A modern ionotropic glutamate receptor with a K(+) selectivity signature sequence.

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21 January 2018

Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors

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21 January 2018

Activation mechanism of the heterodimeric GABA(B) receptor

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21 January 2018

Sweet and umami taste: natural products, their chemosensory targets, and beyond

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21 January 2018

The receptors for mammalian sweet and umami taste

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21 January 2018

Structures of the extracellular regions of the group II/III metabotropic glutamate receptors

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21 January 2018

Structural determinants of natriuretic peptide receptor specificity and degeneracy

1 reference

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21 January 2018

An unusual receptor tyrosine kinase of Schistosoma mansoni contains a Venus Flytrap module.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103236

21 January 2018

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

1 reference

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21 January 2018

Molecular physiology of P2X receptors and ATP signalling at synapses

1 reference

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21 January 2018

A nonproton ligand sensor in the acid-sensing ion channel

1 reference

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21 January 2018

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

1 reference

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21 January 2018

Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH

1 reference

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21 January 2018

The epithelial sodium channel and the control of sodium balance

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21 January 2018

Cellular and Molecular Mechanisms of Pain

1 reference

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21 January 2018

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1 reference

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21 January 2018

TRP channels in mechanosensation: direct or indirect activation?

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201103236

21 January 2018

A light-actuated nanovalve derived from a channel protein

1 reference

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21 January 2018

Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel

1 reference

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21 January 2018

Chemically charging the pore constriction opens the mechanosensitive channel MscL.

1 reference

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21 January 2018

Hydrophilicity of a single residue within MscL correlates with increased channel mechanosensitivity

1 reference

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21 January 2018

Lipid-mediated light activation of a mechanosensitive channel of large conductance

1 reference

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21 January 2018

Alpha-Helix folding in the presence of structural constraints.

1 reference

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21 January 2018

Light-induced control of protein translocation by the SecYEG complex.

1 reference

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21 January 2018

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

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21 January 2018

Engineering GPCR signaling pathways with RASSLs

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21 January 2018

All optical interface for parallel, remote, and spatiotemporal control of neuronal activity

1 reference

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21 January 2018

Next-generation optical technologies for illuminating genetically targeted brain circuits

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21 January 2018

Advances in light microscopy for neuroscience

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21 January 2018

LiGluR restores visual responses in rodent models of inherited blindness

1 reference

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21 January 2018

Chemical and genetic engineering of selective ion channel-ligand interactions

1 reference

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21 January 2018

Response of acetylcholine receptors to rapid photochemically produced increases in agonist concentration

1 reference

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21 January 2018

Identifiers

10.1002/ANIE.201103236

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

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