(Q37963519)

26 August 2017

title

Molecular changes in smoking-related lung cancer (English)

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26 August 2017

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Shahnaz Begum

1

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26 August 2017

publication date

1 January 2012

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Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

26 August 2017

published in

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26 August 2017

volume

12

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26 August 2017

issue

1

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26 August 2017

page(s)

93-106

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An epigenetic marker panel for detection of lung cancer using cell-free serum DNA.

26 August 2017

cites work

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Genetic and epigenetic analysis of erbB signaling pathway genes in lung cancer

21 January 2018

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Molecular analysis of plasma DNA for the early detection of lung cancer by quantitative methylation-specific PCR

21 January 2018

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Association between lifestyle factors and CpG island methylation in a cancer-free population.

21 January 2018

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A gene expression signature predicts survival of patients with stage I non-small cell lung cancer

21 January 2018

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Prediction of lymph node metastasis by analysis of gene expression profiles in primary lung adenocarcinomas.

21 January 2018

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Molecular characteristics predict clinical outcomes: prospective trial correlating response to the EGFR tyrosine kinase inhibitor gefitinib with the presence of sensitizing mutations in the tyrosine binding domain of the EGFR gene

21 January 2018

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Quantitative puff-by-puff-resolved characterization of selected toxic compounds in cigarette mainstream smoke.

21 January 2018

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A review of the influence of particle size, puff volume, and inhalation pattern on the deposition of cigarette smoke particles in the respiratory tract

21 January 2018

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21 January 2018

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Effects of prenatal exposure to cigarette smoke on offspring tumor susceptibility and associated immune mechanisms

21 January 2018

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Chromosomal aberrations of malignant pleural effusions of lung adenocarcinoma: different cytogenetic changes are correlated with genders and smoking habits.

21 January 2018

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Alterations of 9p in squamous cell carcinoma and adenocarcinoma of the lung: association with smoking, TP53, and survival

21 January 2018

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Identification of tumor suppressor loci on the long arm of chromosome 5 in pulmonary large cell neuroendocrine carcinoma.

21 January 2018

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Loss of heterozygosity (LOH) in non-small cell lung cancer: difference between adenocarcinoma and squamous cell carcinoma.

21 January 2018

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Relationship between TP53 tumour suppressor gene mutations and smoking-related bulky DNA adducts in a lung cancer study population from Hungary.

21 January 2018

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Quantitative detection of p53 mutations in plasma DNA from tobacco smokers

21 January 2018

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Molecular footprints of human lung cancer progression

21 January 2018

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On the origin of G --> T transversions in lung cancer

21 January 2018

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TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: distinct patterns in never, former, and current smokers

21 January 2018

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Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke

21 January 2018

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Targeting of lung cancer mutational hotspots by polycyclic aromatic hydrocarbons

21 January 2018

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The TP53 gene, tobacco exposure, and lung cancer

21 January 2018

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The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity

21 January 2018

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LKB1 modulates lung cancer differentiation and metastasis

21 January 2018

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LKB1 and lung cancer: more than the usual suspects

21 January 2018

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Prevalence and specificity of LKB1 genetic alterations in lung cancers

21 January 2018

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Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients

21 January 2018

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FOXO3 encodes a carcinogen-activated transcription factor frequently deleted in early-stage lung adenocarcinoma

21 January 2018

1 reference

PTEN mutations and relationship to EGFR, ERBB2, KRAS, and TP53 mutations in non-small cell lung cancers.

21 January 2018

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Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features

21 January 2018

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K-ras and p53 mutations are an independent unfavourable prognostic indicator in patients with non-small-cell lung cancer

21 January 2018

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Early glandular neoplasia of the lung

21 January 2018

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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

21 January 2018

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A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant K-ras

21 January 2018

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A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

21 January 2018

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Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations

21 January 2018

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Ethnic differences and functional analysis of MET mutations in lung cancer

21 January 2018

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Mutation and cancer: statistical study of retinoblastoma

21 January 2018

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DNA methylation disturbances as novel therapeutic target in lung cancer: preclinical and clinical results

21 January 2018

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Epigenetics of lung cancer

21 January 2018

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Dose effect of smoking on aberrant methylation in non-small cell lung cancers

21 January 2018

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Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer

21 January 2018

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Aberrant promoter methylation of p16 and MGMT genes in lung tumors from smoking and never-smoking lung cancer patients

21 January 2018

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DNMT3B polymorphisms and risk of primary lung cancer

21 January 2018

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Epigenetic tête-à-tête: the bilateral relationship between chromatin modifications and DNA methylation

21 January 2018

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Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer.

21 January 2018

1 reference

Utilization of chromatin remodeling agents for lung cancer therapy

21 January 2018

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Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer

21 January 2018

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Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer.

21 January 2018

1 reference

Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate.

21 January 2018

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Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer.

21 January 2018

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Tobacco smoke induces polycomb-mediated repression of Dickkopf-1 in lung cancer cells

21 January 2018

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Epigenetic mediated transcriptional activation of WNT5A participates in arsenical-associated malignant transformation

21 January 2018

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Effects of nickel, chromate, and arsenite on histone 3 lysine methylation

21 January 2018

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Carcinogen-induced gene promoter hypermethylation is mediated by DNMT1 and causal for transformation of immortalized bronchial epithelial cells

21 January 2018

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Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer

21 January 2018

1 reference

Free radicals and antioxidants in normal physiological functions and human disease

21 January 2018

1 reference

Time-dependent formation of 8-oxo-deoxyguanosine in the lungs of mice exposed to cigarette smoke

21 January 2018

1 reference

Acute effects of cigarette smoke on inflammation and oxidative stress: a review

21 January 2018

1 reference

How cigarette smoke skews immune responses to promote infection, lung disease and cancer

21 January 2018

1 reference

Antioxidant therapeutic targets in COPD.

21 January 2018

1 reference

Nicotine could augment adhesion molecule expression in human endothelial cells through macrophages secreting TNF-alpha, IL-1beta

21 January 2018

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Matrix metalloproteinase/epidermal growth factor receptor/mitogen-activated protein kinase signaling regulate fra-1 induction by cigarette smoke in lung epithelial cells

21 January 2018

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Nicotine enhances angiotensin II-induced mitogenic response in vascular smooth muscle cells and fibroblasts

21 January 2018

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Tobacco carcinogen-induced cellular transformation increases activation of the phosphatidylinositol 3'-kinase/Akt pathway in vitro and in vivo

21 January 2018

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Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells

21 January 2018

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MicroRNA-218 is deleted and downregulated in lung squamous cell carcinoma

21 January 2018

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MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium

21 January 2018

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Expression of miRNA-130a in nonsmall cell lung cancer

21 January 2018

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MicroRNA expression differentiates histology and predicts survival of lung cancer

21 January 2018

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Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke

21 January 2018

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The impact of sex and smoking status on the mutational spectrum of epidermal growth factor receptor gene in non small cell lung cancer.

21 January 2018

1 reference

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

21 January 2018

1 reference

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

21 January 2018

1 reference

Lung cancer susceptibility locus at 5p15.33

21 January 2018

1 reference

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

21 January 2018

1 reference

The relative toxicity of compounds in mainstream cigarette smoke condensate

21 January 2018

1 reference

Aryl hydrocarbon receptor gene polymorphisms affect lung cancer risk.

21 January 2018

1 reference

Heme oxygenase-1 and carbon monoxide: emerging therapeutic targets in inflammation and allergy

21 January 2018

1 reference

4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease

21 January 2018

1 reference

Expression and carbonylation of creatine kinase in the quadriceps femoris muscles of patients with chronic obstructive pulmonary disease

21 January 2018

1 reference

Is cancer triggered by altered signalling of nicotinic acetylcholine receptors?

21 January 2018

1 reference

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers

21 January 2018

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LKB1 gene alterations in surgically resectable adenocarcinoma of the lung.

21 January 2018

1 reference

Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns

21 January 2018

1 reference

Methylation induced gene silencing of HtrA3 in smoking-related lung cancer

21 January 2018

1 reference

The methylation status and protein expression of CDH1, p16(INK4A), and fragile histidine triad in nonsmall cell lung carcinoma: epigenetic silencing, clinical features, and prognostic significance

21 January 2018

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Hypermethylation of the TSLC1/IGSF4 promoter is associated with tobacco smoking and a poor prognosis in primary nonsmall cell lung carcinoma.

21 January 2018

1 reference

Suppression of human IL-1β, IL-2, IFN-γ, and TNF-α production by cigarette smoke extracts

21 January 2018

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Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

21 January 2018

1 reference

Mutational and Epigenetic Evidence for Independent Pathways for Lung Adenocarcinomas Arising in Smokers and Never Smokers

21 January 2018

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Conserved Histone Variant H2A.Z Protects Euchromatin from the Ectopic Spread of Silent Heterochromatin

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ERM.11.84

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release_itcs5mhoejektcqrjux3ntruza

26 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/itcs5mhoejektcqrjux3ntruza

mapped directly with Wikidata item

24 November 2022

based on heuristic

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