(Q37963912)

26 August 2017

title

Bioanalytical aspects of clinical mass balance studies in oncology (English)

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26 August 2017

4

Jos H Beijnen

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26 August 2017

3

Jan H M Schellens

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26 August 2017

author name string

Anne-Charlotte Dubbelman

series ordinal

1

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26 August 2017

Hilde Rosing

series ordinal

2

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26 August 2017

publication date

1 December 2011

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26 August 2017

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26 August 2017

volume

3

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26 August 2017

issue

23

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26 August 2017

page(s)

2637-2655

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Mass balance studies, with a focus on anticancer drugs.

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Oxazaphosphorines: new therapeutic strategies for an old class of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Liquid chromatography-mass spectrometry for the quantitative bioanalysis of anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

A novel strategy for reducing phospholipids-based matrix effect in LC-ESI-MS bioanalysis by means of HybridSPE.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Recent advances in sample preparation techniques for effective bioanalytical methods

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Progress in automation of LC-MS in laboratory medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

High-throughput quantification of the anti-leukemia drug STI571 (Gleevec) and its main metabolite (CGP 74588) in human plasma using liquid chromatography-tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Trabectedin (Yondelis, formerly ET-743), a mass balance study in patients with advanced cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Simple and sensitive liquid chromatographic quantitative analysis of the novel marine anticancer drug Yondelis (ET-743, trabectedin) in human plasma using column switching and tandem mass spectrometric detection

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Quantitative bioanalytical methods validation and implementation: best practices for chromatographic and ligand binding assays

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Potential bias and mitigations when using stable isotope labeled parent drug as internal standard for LC-MS/MS quantitation of metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Stable-isotope dilution LC–MS for quantitative biomarker analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Simultaneous quantification of 2',2'-difluorodeoxycytidine and 2',2'-difluorodeoxyuridine nucleosides and nucleotides in white blood cells using porous graphitic carbon chromatography coupled with tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Quantitation of small molecules using high-resolution accurate mass spectrometers - a different approach for analysis of biological samples

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Systematic LC-MS/MS bioanalytical method development that incorporates plasma phospholipids risk avoidance, usage of incurred sample and well thought-out chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Impact of glucuronide interferences on therapeutic drug monitoring of posaconazole by tandem mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Fragmentation of N-oxides (deoxygenation) in atmospheric pressure ionization: investigation of the activation process

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Applicability of bioanalysis of multiple analytes in drug discovery and development: review of select case studies including assay development considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Challenges in urine bioanalytical assays: overcoming nonspecific binding

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Metabolism of trabectedin (ET-743, Yondelis) in patients with advanced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Metabolism and Disposition of [14C]BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor Inhibitor, after Oral Administration to Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Pharmacokinetics and metabolism of BIBF 1120 after oral dosing to healthy male volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Assessing the matrix effects of hemolyzed samples in bioanalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Obtaining exposures of metabolites in preclinical species through plasma pooling and quantitative NMR: addressing metabolites in safety testing (MIST) guidance without using radiolabeled compounds and chemically synthesized metabolite standards.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Metabolism and disposition of vatalanib (PTK787/ZK-222584) in cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Analysis of low level radioactive metabolites in biological fluids using high-performance liquid chromatography with microplate scintillation counting: method validation and application

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Radiocarbon dating using electrostatic accelerators: negative ions provide the key.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Accelerator mass spectrometry in biomedical dosimetry: relationship between low-level exposure and covalent binding of heterocyclic amine carcinogens to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Accelerator mass spectrometry-enabled studies: current status and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Analytical validation of accelerator mass spectrometry for pharmaceutical development

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Accelerator mass spectrometry best practices for accuracy and precision in bioanalytical (14)C measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Early human ADME using microdoses and microtracers: bioanalytical considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Human mass balance study of the novel anticancer agent ixabepilone using accelerator mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Metabolism, excretion, and pharmacokinetics of oral brivanib in patients with advanced or metastatic solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Approaches for the rapid identification of drug metabolites in early clinical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Drug metabolite profiling and identification by high-resolution mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Challenges and solutions to metabolites in safety testing: impact of the International Conference on Harmonization M3(R2) guidance

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Comparative biotransformation of radiolabeled [(14)C]omapatrilat and stable-labeled [(13)C(2)]omapatrilat after oral administration to rats, dogs, and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

On-line liquid chromatography-accurate radioisotope counting coupled with a radioactivity detector and mass spectrometer for metabolite identification in drug discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

An excretion balance and pharmacokinetic study of the novel anticancer agent E7070 in cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Microdose study of 14C-acetaminophen with accelerator mass spectrometry to examine pharmacokinetics of parent drug and metabolites in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Practical experience of using human microdosing with AMS analysis to obtain early human drug metabolism and PK data

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

An accurate-mass-based spectral-averaging isotope-pattern-filtering algorithm for extraction of drug metabolites possessing a distinct isotope pattern from LC-MS data

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Mass defect filter technique and its applications to drug metabolite identification by high-resolution mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Metabolism and disposition of imatinib mesylate in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer a

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.276

21 January 2018

Identifiers

DOI

10.4155/BIO.11.276

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26 August 2017

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