(Q37964746)

26 August 2017

Failure of innate and adaptive immune responses in controlling hepatitis C virus infection (English)

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26 August 2017

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2

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26 August 2017

Ralf Bartenschlager

3

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author name string

Robert Thimme

series ordinal

1

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26 August 2017

4 January 2012

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FEMS Microbiology Reviews

26 August 2017

1 reference

26 August 2017

36

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26 August 2017

3

1 reference

26 August 2017

663-683

1 reference

Intrahepatic virus-specific IL-10-producing CD8 T cells prevent liver damage during chronic hepatitis C virus infection

26 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Natural killer cells are polarized toward cytotoxicity in chronic hepatitis C in an interferon-alfa-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C Virus Genotype 1a Growth and Induction of Autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Activation of natural killer cells during acute infection with hepatitis C virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus controls interferon production through PKR activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus hypervariable region 1 modulates receptor interactions, conceals the CD81 binding site, and protects conserved neutralizing epitopes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

In vitro assay for neutralizing antibody to hepatitis C virus: Evidence for broadly conserved neutralization epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Cleavage of mitochondrial antiviral signaling protein in the liver of patients with chronic hepatitis C correlates with a reduced activation of the endogenous interferon system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Analysis of CD127 and KLRG1 expression on hepatitis C virus-specific CD8+ T cells reveals the existence of different memory T-cell subsets in the peripheral blood and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

DNA microarray analysis of chimpanzee liver during acute resolving hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus escape from the interferon regulatory factor 3 pathway by a passive and active evasion strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Expression of hepatitis c virus proteins inhibits interferon alpha signaling in the liver of transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Mutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to man

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Variable Patterns of Programmed Death-1 Expression on Fully Functional Memory T Cells after Spontaneous Resolution of Hepatitis C Virus Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Secondary structure of the 5' nontranslated regions of hepatitis C virus and pestivirus genomic RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Failure to infect rhesus monkeys with hepatitis C virus strains of genotypes 1a, 2a or 3a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

A siege of hepatitis: immune boost for viral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Natural killer cells and hepatitis C: action and reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatic gene expression discriminates responders and nonresponders in treatment of chronic hepatitis C viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Unscrambling hepatitis C virus-host interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Analysis of a successful immune response against hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Comprehensive analyses of CD8+ T cell responses during longitudinal study of acute human hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Cellular immune selection with hepatitis C virus persistence in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Liver antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Inhibition of Natural Killer Cells through Engagement of CD81 by the Major Hepatitis C Virus Envelope Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virions subvert natural killer cell activation to generate a cytokine environment permissive for infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Interferons and microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Broad Specificity of Virus-Specific CD4+ T-Helper-Cell Responses in Resolved Hepatitis C Virus Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27–restricted human immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Selection pressure from neutralizing antibodies drives sequence evolution during acute infection with hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

The autophagy machinery is required to initiate hepatitis C virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C Virus Envelope Glycoprotein E2 Glycans Modulate Entry, CD81 Binding, and Neutralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Activation of natural killer cells by hepatitis C virus particles in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Virological footprint of CD4+ T-cell responses during chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus infection of neuroepithelioma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Interferon-gamma inhibits replication of subgenomic and genomic hepatitis C virus RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Selection-driven immune escape is not a significant factor in the failure of CD4 T cell responses in persistent hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Evidence of Viral Adaptation to HLA Class I-Restricted Immune Pressure in Chronic Hepatitis C Virus Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Association of hepatitis C virus-specific CD8+ T cells with viral clearance in acute hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Mechanism of the interferon alpha response against hepatitis C virus replicons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

FOXP3 expression in hepatitis C virus-specific CD4+ T cells during acute hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Analysis of ISG expression in chronic hepatitis C identifies viperin as a potential antiviral effector

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

The Neutralizing Activity of Anti-Hepatitis C Virus Antibodies Is Modulated by Specific Glycans on the E2 Envelope Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Human leukocyte antigen class II DQB1*0301, DRB1*1101 alleles and spontaneous clearance of hepatitis C virus infection: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Analysis of CD8+ T-cell-mediated inhibition of hepatitis C virus replication using a novel immunological model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Experimental models to study the immunobiology of hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

PKR protein kinase is activated by hepatitis C virus and inhibits viral replication through translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Discordant role of CD4 T-cell response relative to neutralizing antibody and CD8 T-cell responses in acute hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Escape mutations alter proteasome processing of major histocompatibility complex class I-restricted epitopes in persistent hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Consistent beneficial effects of killer cell immunoglobulin-like receptor 2DL3 and group 1 human leukocyte antigen-C following exposure to hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Specific human leukocyte antigen class I and II alleles associated with hepatitis C virus viremia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Cytokine-activated natural killer cells exert direct killing of hepatoma cells harboring hepatitis C virus replicons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Comprehensive Analysis of CD8+-T-Cell Responses against Hepatitis C Virus Reveals Multiple Unpredicted Specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Analysis of successful immune responses in persons infected with hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Autophagy-dependent viral recognition by plasmacytoid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Natural killer cells inhibit hepatitis C virus expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Neutralizing antibody response during acute and chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

HCV structural proteins interfere with interferon-alpha Jak/STAT signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus kinetics and host responses associated with disease and outcome of infection in chimpanzees

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Small self-RNA generated by RNase L amplifies antiviral innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Cell culture-produced hepatitis C virus does not infect peripheral blood mononuclear cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Effect of immune pressure on hepatitis C virus evolution: insights from a single-source outbreak

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Limited T Cell Receptor Diversity of HCV-specific T Cell Responses Is Associated with CTL Escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

HLA-C and KIR genes in hepatitis C virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Humoral immune response in acute hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Spontaneous control of primary hepatitis C virus infection and immunity against persistent reinfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Regulation of PKR and IRF-1 during hepatitis C virus RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

New insights into structure and replication of the hepatitis C virus and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Quantitative Analysis of the Hepatitis C Virus Replication Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Impaired Hepatitis C Virus (HCV)-Specific Effector CD8+ T Cells Undergo Massive Apoptosis in the Peripheral Blood during Acute HCV Infection and in the Liver during the Chronic Phase of Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Influence of inhibitory killer immunoglobulin-like receptors and their HLA-C ligands on resolving hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Divergent and convergent evolution after a common-source outbreak of hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Interaction of NK inhibitory receptor genes with HLA-C and MHC class II alleles in Hepatitis C virus infection outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

CD8+ T-cell response promotes evolution of hepatitis C virus nonstructural proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Neutralizing monoclonal antibodies against hepatitis C virus E2 protein bind discontinuous epitopes and inhibit infection at a postattachment step

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Regulation of innate immune responses by autophagy-related proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Interferon signaling and treatment outcome in chronic hepatitis C

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Inteferons pen the JAK-STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Host genetics in immune-mediated hepatitis C virus clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

A diverse range of gene products are effectors of the type I interferon antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Preferential loss of IL-2-secreting CD4+ T helper cells in chronic HCV infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus (HCV) evades NKG2D-dependent NK cell responses through NS5A-mediated imbalance of inflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Global epidemiology of hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

IL-28, IL-29 and their class II cytokine receptor IL-28R

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Delayed induction, not impaired recruitment, of specific CD8⁺ T cells causes the late onset of acute hepatitis C

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Regulation of gene-activation pathways by PIAS proteins in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Autophagy in viral replication and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Functional suppression by FoxP3+CD4+CD25(high) regulatory T cells during acute hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Relation between viral fitness and immune escape within the hepatitis C virus protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

IFN-lambda (IFN-lambda) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Interferon-alpha-induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Nonlinear partial differential equations and applications: Genomic analysis of the host response to hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Immune evasion versus recovery after acute hepatitis C virus infection from a shared source

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Determinants of viral clearance and persistence during acute hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

HLA-Cw*04 and hepatitis C virus persistence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

CD8 Epitope Escape and Reversion in Acute HCV Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Human leukocyte antigen-associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Binding of the Hepatitis C Virus Envelope Protein E2 to CD81 Inhibits Natural Killer Cell Functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

The impairment of CD8 responses limits the selection of escape mutations in acute hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Adaptive immunity to the hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Alpha interferon induces distinct translational control programs to suppress hepatitis C virus RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Mitochondria in innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Transmission of hepatitis C virus infection to tree shrews

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Efficient infection of tree shrew (Tupaia belangeri) with hepatitis C virus grown in cell culture or from patient plasma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

RNA recognition and signal transduction by RIG-I-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Natural killer cell function is intact after direct exposure to infectious hepatitis C virions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

SOCS proteins, cytokine signalling and immune regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Host neutralizing responses and pathogenesis of hepatitis C virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus epitope-specific neutralizing antibodies in Igs prepared from human plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatitis C virus lymphotropism: lessons from a decade of studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

Hepatic expansion of a virus-specific regulatory CD8+ T cell population in chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2011.00319.X

10.1111/J.1574-6976.2011.00319.X

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22142141