(Q37980338)

26 August 2017

Hypoxia--a key regulator of angiogenesis and inflammation in rheumatoid arthritis (English)

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26 August 2017

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3

Ewa M Paleolog

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26 August 2017

2

Serafim Kiriakidis

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26 August 2017

Sofia Konisti

1

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PubMed ID

22293762

26 August 2017

language of work or name

English

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publication date

31 January 2012

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Nature Reviews Rheumatology

26 August 2017

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26 August 2017

8

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26 August 2017

3

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26 August 2017

153-162

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https://scigraph.springernature.com/pub.10.1038/nrrheum.2011.205

26 August 2017

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31 March 2020

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31 March 2020

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NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

31 March 2020

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The involvement of hypoxia-inducible factor 1 alpha in Toll-like receptor 7/8-mediated inflammatory response.

31 March 2020

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Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expression

31 March 2020

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Cutting edge: Essential role of hypoxia inducible factor-1alpha in development of lipopolysaccharide-induced sepsis

31 March 2020

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The role of redox-dependent mechanisms in the downregulation of ligand-induced Toll-like receptors 7, 8 and 4-mediated HIF-1 alpha prolyl hydroxylation

31 March 2020

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Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions

31 March 2020

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Hypoxia affects cytokine production and proliferative responses by human peripheral mononuclear cells

31 March 2020

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Differential in vitro effects of physiological and atmospheric oxygen tension on normal human peripheral blood mononuclear cell proliferation, cytokine and immunoglobulin production

31 March 2020

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Hypoxia-inducible factor regulates survival of antigen receptor-driven T cells

31 March 2020

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TCR engagement increases hypoxia-inducible factor-1 alpha protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells

31 March 2020

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Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1

31 March 2020

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HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

31 March 2020

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Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy

31 March 2020

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The chemokine system in diverse forms of macrophage activation and polarization

31 March 2020

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Knockout of HIF-1α in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses

31 March 2020

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The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

31 March 2020

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Genetic amplification of the transcriptional response to hypoxia as a novel means of identifying regulators of angiogenesis.

31 March 2020

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Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation

31 March 2020

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Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis

31 March 2020

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Expression of HIF-1alpha by human macrophages: implications for the use of macrophages in hypoxia-regulated cancer gene therapy

31 March 2020

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Effects of hypoxia on transcription factor expression in human monocytes and macrophages

31 March 2020

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Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia

31 March 2020

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HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

31 March 2020

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Opposing roles for HIF-1α and HIF-2α in the regulation of angiogenesis by mononuclear phagocytes

31 March 2020

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Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression

31 March 2020

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The molecular signature of oxidative metabolism and the mode of macrophage activation determine the shift from acute to chronic disease in experimental arthritis: critical role of interleukin-12p40

31 March 2020

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Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis

31 March 2020

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Ascorbate deficiency results in impaired neutrophil apoptosis and clearance and is associated with up-regulation of hypoxia-inducible factor 1alpha

31 March 2020

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Divergent effects of hypoxia on dendritic cell functions

31 March 2020

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Hypoxia inducible factor (HIF)-1 coordinates induction of Toll-like receptors TLR2 and TLR6 during hypoxia

31 March 2020

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Hypoxia and hypoxia-inducible factor-1 alpha modulate lipopolysaccharide-induced dendritic cell activation and function

31 March 2020

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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

31 March 2020

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Bevacizumab improves the overall and progression-free survival of patients with metastatic colorectal cancer treated with 5-fluorouracil-based regimens irrespective of baseline risk

31 March 2020

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Vascular endothelial growth factor expression and regulation of murine collagen-induced arthritis

31 March 2020

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Neutralization of Vascular Endothelial Growth Factor Prevents Collagen-Induced Arthritis and Ameliorates Established Disease in Mice

31 March 2020

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Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

31 March 2020

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Adenoviral delivery of soluble VEGF receptor 1 (sFlt-1) abrogates disease activity in murine collagen-induced arthritis

31 March 2020

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Blockade of Vascular Endothelial Growth Factor Receptor I (VEGF-RI), but not VEGF-RII, Suppresses Joint Destruction in the K/BxN Model of Rheumatoid Arthritis

31 March 2020

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Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab

31 March 2020

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Cardiovascular, rheumatologic, and pharmacologic predictors of stroke in patients with rheumatoid arthritis: a nested, case-control study

31 March 2020

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Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis

31 March 2020

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Multihistology, target-driven pilot trial of oral topotecan as an inhibitor of hypoxia-inducible factor-1α in advanced solid tumors

31 March 2020

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Pleiotropic effects of YC-1 selectively inhibit pathological retinal neovascularization and promote physiological revascularization in a mouse model of oxygen-induced retinopathy

31 March 2020

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Inhibition of histone deacetylase down-regulates the expression of hypoxia-induced vascular endothelial growth factor by rheumatoid synovial fibroblasts

31 March 2020

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Inhibition of HIF-1alpha activity by BP-1 ameliorates adjuvant induced arthritis in rats

31 March 2020

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Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

31 March 2020

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Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis.

31 March 2020

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The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis.

31 March 2020

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Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition.

31 March 2020

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Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function

31 March 2020

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Therapeutic manipulation of the HIF hydroxylases

31 March 2020

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Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2011.205

31 March 2020

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Regulation of oxygen homeostasis by hypoxia-inducible factor 1.

31 March 2020

1 reference

12 December 2020

Hypoxia inducible factor-1-alpha (HIF-1alpha) is related to both angiogenesis and inflammation in rheumatoid arthritis

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12 December 2020

Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.

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12 December 2020

Interleukin 1 induces hypoxia-inducible factor 1 in human gingival and synovial fibroblasts

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12 December 2020

Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues.

1 reference

12 December 2020

Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.

1 reference

12 December 2020

Hypoxia affects cytokine production and proliferative responses by human peripheral mononuclear cells

1 reference

12 December 2020

Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis

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12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2011.205

1 reference

26 August 2017

1 reference

PubMed ID

22293762