(Q37981836)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Copper-dependent regulation of NMDA receptors by cellular prion protein: implications for neurodegenerative disorders (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

0 references

1 reference

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Peter K Stys

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Haitao You

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

6 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

published in

Journal of Physiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

590

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

1357-1368

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json

Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions

22 January 2020

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Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein

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Axonal prion protein is required for peripheral myelin maintenance

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The cellular prion protein binds copper in vivo

21 January 2018

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Copper-dependent functions for the prion protein

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Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

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Prion protein and Abeta-related synaptic toxicity impairment

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Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions

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Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits

21 January 2018

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Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo

21 January 2018

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Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

21 January 2018

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Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor.

21 January 2018

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Prion protein is necessary for normal synaptic function

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Synaptic plasticity. The role of NMDA receptors in learning and memory.

21 January 2018

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A nomenclature for ligand-gated ion channels

21 January 2018

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Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons

21 January 2018

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Age-dependent loss of PTP and LTP in the hippocampus of PrP-null mice.

21 January 2018

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Drug delivery strategies for Alzheimer's disease treatment.

21 January 2018

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Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors.

21 January 2018

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N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease

21 January 2018

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Mechanisms of copper ion mediated Huntington's disease progression

21 January 2018

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Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

21 January 2018

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Depressive-like behaviour of mice lacking cellular prion protein

21 January 2018

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Cellular prion protein protects from inflammatory and neuropathic pain

21 January 2018

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Unconventional Viruses and the Origin and Disappearance of Kuru

21 January 2018

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Memory impairment in transgenic Alzheimer mice requires cellular prion protein

21 January 2018

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Decreased cell surface prion protein in mouse models of prion disease.

21 January 2018

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Prion protein affects Ca2+-activated K+ currents in cerebellar purkinje cells

21 January 2018

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Frequency-dependent involvement of NMDA receptors in the hippocampus: a novel synaptic mechanism.

21 January 2018

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Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

PrPC interacts with potassium channel tetramerization domain containing 1 (KCTD1) protein through the PrP(51-136) region containing octapeptide repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

Location and properties of metal-binding sites on the human prion protein.

21 January 2018

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Divalent metals differentially block cloned T-type calcium channels

21 January 2018

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Synaptic plasticity in the CA1 area of the hippocampus of scrapie-infected mice.

21 January 2018

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NMDA receptors in clinical neurology: excitatory times ahead

21 January 2018

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The prion protein as a receptor for amyloid-beta.

21 January 2018

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Prion protein attenuates excitotoxicity by inhibiting NMDA receptors

21 January 2018

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Modulation of L‐type voltage‐gated calcium channels by recombinant prion protein

21 January 2018

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Mg2+ imparts NMDA receptor subtype selectivity to the Alzheimer's drug memantine

21 January 2018

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Probing the pore region of recombinant N-methyl-D-aspartate channels using external and internal magnesium block

21 January 2018

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Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

21 January 2018

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Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor

21 January 2018

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Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

21 January 2018

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Physiology of the prion protein

21 January 2018

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Excitatory amino acids as a final common pathway for neurologic disorders.

21 January 2018

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Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

21 January 2018

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Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex

21 January 2018

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NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo.

21 January 2018

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The N-methyl-D-aspartate receptor subunit NR2B: localization, functional properties, regulation, and clinical implications.

21 January 2018

1 reference

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New insights into the not-so-new NR3 subunits of N-methyl-D-aspartate receptor: localization, structure, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

Enhancement of glutamate release uncovers spillover-mediated transmission by N-methyl-D-aspartate receptors in the rat hippocampus.

21 January 2018

1 reference

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Effects of copper on T-type Ca2+ channels in mouse spermatogenic cells.

21 January 2018

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Hippocampal long-term synaptic plasticity and signal amplification of NMDA receptors

21 January 2018

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Inherited prion disease with an alanine to valine mutation at codon 117 in the prion protein gene

21 January 2018

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Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

21 January 2018

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Regulation of NMDA receptor desensitization in mouse hippocampal neurons by glycine.

21 January 2018

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Copper and the prion protein: methods, structures, function, and disease

21 January 2018

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Identification by mutagenesis of a Mg(2+)-block site of the NMDA receptor channel

21 January 2018

1 reference

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Cytoprotective effect of NMDA receptor antagonists on prion protein (PrionSc)-induced toxicity in rat cortical cell cultures.

21 January 2018

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Developmental changes in the expression of ATP7A during a critical period in postnatal neurodevelopment.

21 January 2018

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Prion protein is necessary for latent learning and long-term memory retention.

21 January 2018

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Magnesium gates glutamate-activated channels in mouse central neurones

21 January 2018

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Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

21 January 2018

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Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

21 January 2018

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Molecular basis of NMDA receptor functional diversity.

21 January 2018

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NMDA receptor subunits: function and pharmacology.

21 January 2018

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Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons

21 January 2018

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Excitatory glycine responses of CNS myelin mediated by NR1/NR3 "NMDA" receptor subunits

21 January 2018

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Prion diseases and the BSE crisis

21 January 2018

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The micromolar zinc-binding domain on the NMDA receptor subunit NR2B.

21 January 2018

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Enhanced susceptibility of Prnp-deficient mice to kainate-induced seizures, neuronal apoptosis, and death: Role of AMPA/kainate receptors.

21 January 2018

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Regulation of GABA(A) and glutamate receptor expression, synaptic facilitation and long-term potentiation in the hippocampus of prion mutant mice

21 January 2018

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Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-D-aspartate receptor population in adult hippocampal synapses

21 January 2018

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Biochemistry and structure of PrPC and PrPSc

21 January 2018

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No propagation of prions in mice devoid of PrP.

21 January 2018

1 reference

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Cellular signalling pathways of spinal pain neuroplasticity as targets for analgesic development

21 January 2018

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Role of the CaMKII/NMDA receptor complex in the maintenance of synaptic strength

21 January 2018

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Astrocytic regulation of NMDA receptor subunit composition modulates the toxicity of prion peptide PrP106-126.

21 January 2018

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https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

NMDA receptor activation mediates copper homeostasis in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

Copper homeostasis in the CNS: a novel link between the NMDA receptor and copper homeostasis in the hippocampus

21 January 2018

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Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity

21 January 2018

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D-serine is the dominant endogenous coagonist for NMDA receptor neurotoxicity in organotypic hippocampal slices.

21 January 2018

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Free-radical generation by copper ions and hydrogen peroxide. Stimulation by Hepes buffer

21 January 2018

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Regulation of NMDA receptor trafficking by amyloid-beta

21 January 2018

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The prion protein knockout mouse: a phenotype under challenge

21 January 2018

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Functional roles of cytoplasmic loops and pore lining transmembrane helices in the voltage-dependent inactivation of HVA calcium channels.

21 January 2018

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Why glycine transporters have different stoichiometries.

21 January 2018

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Amyloid β peptide oligomers directly activate NMDA receptors.

21 January 2018

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Synaptic and extrasynaptic NMDA receptor NR2 subunits in cultured hippocampal neurons

21 January 2018

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Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain

21 January 2018

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Regulation of NMDA receptors by the tyrosine kinase Fyn

21 January 2018

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Absence of the cellular prion protein exacerbates and prolongs neuroinflammation in experimental autoimmune encephalomyelitis

21 January 2018

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21 January 2018

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Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors

21 January 2018

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The multi-layered regulation of copper translocating P-type ATPases

21 January 2018

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Copper modulation of NMDA responses in mouse and rat cultured hippocampal neurons.

21 January 2018

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Modulation of N-methyl-D-aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones

21 January 2018

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The distribution of copper in human brain.

21 January 2018

1 reference

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The effects of copper ions on glutamate receptors in cultured rat cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease

21 January 2018

1 reference

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RNAi for the treatment of prion disease: a window for intervention in neurodegeneration?

21 January 2018

1 reference

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Mapping the antigenicity of copper-treated cellular prion protein with the scrapie isoform.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

Unification of the copper(I) binding affinities of the metallo-chaperones Atx1, Atox1, and related proteins: detection probes and affinity standards.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

Control of excitatory synaptic transmission by C-terminal Src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

Allosteric modulation of NMDA receptor via elevation of brain glycine and D-serine: the therapeutic potentials for schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

Distinct gating modes determine the biphasic relaxation of NMDA receptor currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

N-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer's disease, vascular dementia and Parkinson's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382327

Role of distinct NMDA receptor subtypes at central synapses

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382327

Neuronal glutamate transporters limit activation of NMDA receptors by neurotransmitter spillover on CA1 pyramidal cells.

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382327

Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382327

The cellular prion protein binds copper in vivo

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382327

N-methyl-D-aspartic acid receptor structure and function

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382327

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

16 September 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

The same prion strain causes vCJD and BSE

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.225276

A STUDY OF HUMAN CEREBROSPINAL FLUID: COPPER AND MANGANESE

21 January 2018

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12 December 2020

Zinc and copper in human cerebrospinal fluid

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12 December 2020

Genetic control of scrapie and Creutzfeldt-Jakob disease in mice

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12 December 2020

The synucleins are a family of redox-active copper binding proteins

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12 December 2020

Increased Sensitivity to Seizures in Mice Lacking Cellular Prion Protein

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12 December 2020

Threshold for epileptiform activity is elevated in prion knockout mice

1 reference

12 December 2020

Alzheimer's precursor protein and the use of bathocuproine for determining reduction of copper(II)

1 reference

12 December 2020

Extrasynaptic Glutamate Spillover in the Hippocampus: Dependence on Temperature and the Role of Active Glutamate Uptake

1 reference

12 December 2020

Ternary Coordination Complexes between Glycine, Copper (II), and Glycine Peptides in Aqueous Solution

1 reference

12 December 2020

Copper and zinc as modulators of neuronal excitability in a physiologically significant concentration range

1 reference

12 December 2020

10.1113/JPHYSIOL.2011.225276

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PMC publication ID

3382327

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310309%20AND%20SRC:MED&resulttype=core&format=json