(Q37983700)

26 August 2017

Importance of oestrogen receptors to preserve functional β-cell mass in diabetes (English)

1 reference

26 August 2017

1 reference

Joseph P Tiano

1

1 reference

PubMed ID

22330739

26 August 2017

Franck Mauvais-Jarvis

series ordinal

2

1 reference

26 August 2017

14 February 2012

1 reference

Nature Reviews Endocrinology

26 August 2017

1 reference

26 August 2017

8

1 reference

26 August 2017

6

1 reference

26 August 2017

342-351

1 reference

https://scigraph.springernature.com/pub.10.1038/nrendo.2011.242

26 August 2017

0 references

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The route of administration influences the effect of estrogen on insulin sensitivity in postmenopausal women.

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Insulinotropic effect of ovarian steroid hormones in streptozotocin diabetic female mice

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Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice

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Induction of Insulin-dependent Diabetes by Streptozotocin Inhibition by Estrogens and Potentiation by Androgens

31 March 2020

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Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival

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Androgen sensitization of streptozotocin-induced diabetes in mice

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Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide

31 March 2020

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Oophorectomy promotes islet amyloid formation in a transgenic mouse model of Type II diabetes.

31 March 2020

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Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships

31 March 2020

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Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes

31 March 2020

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Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling.

31 March 2020

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Estrogenic restoration of functional pancreatic islet cytoarchitecture in diabetes (db/db) mutant C57BL/KsJ mice: relationship to estradiol localization, systemic glycemia, and persistent hyperinsulinemia

31 March 2020

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A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice

31 March 2020

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A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse

31 March 2020

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Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

31 March 2020

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Dimorphic gene expression patterns of anorexigenic and orexigenic peptides in hypothalamus account male and female hyperphagia in Akita type 1 diabetic mice.

31 March 2020

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Ablation of estrogen receptor alpha (ERalpha) prevents upregulation of POMC by leptin and insulin

31 March 2020

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OLETF (Otsuka Long-Evans Tokushima Fatty) rat: a new NIDDM rat strain

31 March 2020

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Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain

31 March 2020

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An animal model of congenital defect of gene expression of cholecystokinin (CCK)-A receptor

31 March 2020

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Sexual difference in the incidence of diabetes mellitus in Otsuka-Long-Evans-Tokushima-Fatty rats: effects of castration and sex hormone replacement on its incidence

31 March 2020

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Orchiectomy and response to testosterone in the development of obesity in young Otsuka-Long-Evans-Tokushima Fatty (OLETF) rats

31 March 2020

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Diabetes induced in male transgenic mice by expression of human H-ras oncoprotein in pancreatic beta cells

31 March 2020

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Sexual dimorphism of pancreatic beta-cell degeneration in transgenic mice expressing an insulin-ras hybrid gene

31 March 2020

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Disruption of IRS-2 causes type 2 diabetes in mice

31 March 2020

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IRS-2 pathways integrate female reproduction and energy homeostasis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

31 March 2020

1 reference

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Pdx1 restores beta cell function in Irs2 knockout mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Effects of steroid and lactogenic hormones on islets of Langerhans: a new hypothesis for the role of pregnancy steroids in the adaptation of islets to pregnancy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Adiponectin-induced ERK and Akt phosphorylation protects against pancreatic beta cell apoptosis and increases insulin gene expression and secretion

31 March 2020

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Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Endocrine regulation of energy metabolism by the skeleton

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Rapid insulinotropic effect of 17beta-estradiol via a plasma membrane receptor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor alpha and estrogen receptor beta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Low doses of the endocrine disruptor bisphenol-A and the native hormone 17beta-estradiol rapidly activate transcription factor CREB.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

17beta-Estradiol protects isolated human pancreatic islets against proinflammatory cytokine-induced cell death: molecular mechanisms and islet functionality

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Estrogen modulates xanthine dehydrogenase/xanthine oxidase activity by a receptor-independent mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

The antioxidant effect of estrogen and Selective Estrogen Receptor Modulators in the inhibition of osteocyte apoptosis in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Effects of estrogen on breast cancer development: Role of estrogen receptor independent mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Suppression of the c-Jun N-terminal kinase pathway by 17beta-estradiol can preserve human islet functional mass from proinflammatory cytokine-induced destruction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Rapid, nongenomic estrogen actions protect pancreatic islet survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Insulinotropic and antidiabetic effects of 17β-estradiol and the GPR30 agonist G-1 on human pancreatic islets.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Adenosine 3',5'-monophosphate in rat uterus: acute elevation by estrogen

31 March 2020

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Neuroprotection against oxidative stress by estrogens: structure-activity relationship

31 March 2020

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31 March 2020

12 December 2020

Genistein reduces hyperglycemia and islet cell loss in a high-dosage manner in rats with alloxan-induced pancreatic damage.

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Virtual and biomolecular screening converge on a selective agonist for GPR30.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Relative effects of pregnancy, estradiol, and progesterone on plasma insulin and pancreatic islet insulin secretion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Estrogen and exercise may enhance beta-cell function and mass via insulin receptor substrate 2 induction in ovariectomized diabetic rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Extranuclear estrogen receptor-alpha stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Effects of ovariectomy and treatment with progesterone or oestradiol-17 beta on the secretion of insulin by the perfused rat pancreas

31 March 2020

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Pancreatic insulin content regulation by the estrogen receptor ER alpha

31 March 2020

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Effect of estradiol on insulin secreting INS-1 cells overexpressing estrogen receptors

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

The effects of pregnancy steroids on adaptation of beta cells to pregnancy involve the pancreatic glucose sensor glucokinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Effect of 17beta-estradiol on insulin secretion and cytosolic calcium in Min6 mouse insulinoma cells and human islets of Langerhans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Rapid regulation of K(ATP) channel activity by 17{beta}-estradiol in pancreatic {beta}-cells involves the estrogen receptor {beta} and the atrial natriuretic peptide receptor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Effects of explosive brain death on cytokine activation of peripheral organs in the rat.

31 March 2020

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Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats

31 March 2020

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Enhanced isolated pancreatic islet recovery and functionality in rats by 17beta-estradiol treatment of brain death donors

31 March 2020

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Sexual function and endocrine profile in fertile women with type 1 diabetes

31 March 2020

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Stromal estrogen receptors mediate mitogenic effects of estradiol on uterine epithelium

31 March 2020

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Short-term effects of oestradiol benzoate in normal, hypophysectomized and alloxan-diabetic male rats.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Beneficial effect of 17β-estradiol on hyperglycemia and islet β-cell functions in a streptozotocin-induced diabetic rat model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Oestrogen regulates proliferation and differentiation of human islet-derived precursor cells through oestrogen receptor alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Endometrial cancer and hormone-replacement therapy in the Million Women Study

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

The pairing of a selective estrogen receptor modulator, bazedoxifene, with conjugated estrogens as a new paradigm for the treatment of menopausal symptoms and osteoporosis prevention

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

A new approach to menopausal therapy: the tissue selective estrogen complex

31 March 2020

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Mechanisms of estrogen action

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Plasma membrane estrogen receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. V. Interaction between the db gene and hepatic sex steroid sulfotransferases correlates with gender-dependent susceptibility to hyperglycemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.242

A nonclassical estrogen membrane receptor triggers rapid differential actions in the endocrine pancreas

31 March 2020

1 reference

12 December 2020

Conjugated equine estrogen improves glycemic control and blood lipoproteins in postmenopausal women with type 2 diabetes

1 reference

12 December 2020

Estrogen and type 1 diabetes mellitus.

1 reference

12 December 2020

Effects of low doses of transdermal 17 beta-estradiol on carbohydrate metabolism in postmenopausal women

1 reference

12 December 2020

Sex steroids and insulin resistance

1 reference

12 December 2020

Production or prevention of some types of experimental diabetes by oestrogens or corticosteroids

1 reference

12 December 2020

Preliminary report: effects of female sex hormones on insulin secretion by the perfused rat pancreas

1 reference

12 December 2020

Insulin secretion from isolated pancreatic islets in the female rat. Short and long term oestradiol influence

1 reference

12 December 2020

Insulinotropic hormone glucagon-like peptide-I(7-37) stimulation of proinsulin gene expression and proinsulin biosynthesis in insulinoma beta TC-1 cells

1 reference

12 December 2020

Estrogen replacement therapy decreases hyperandrogenicity and improves glucose homeostasis and plasma lipids in postmenopausal women with noninsulin-dependent diabetes mellitus.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRENDO.2011.242

1 reference

26 August 2017

1 reference

PubMed ID

22330739