(Q37987877)

26 August 2017

title

Gene expression-targeted isoflavone therapy (English)

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26 August 2017

1

Alicja Węgrzyn

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26 August 2017

publication date

23 February 2012

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26 August 2017

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volume

64

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issue

4

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26 August 2017

page(s)

307-315

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Gene therapy: some history, applications, problems, and prospects

26 August 2017

cites work

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Clarifying lysosomal storage diseases

21 January 2018

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Substrate reduction therapies for mucopolysaccharidoses

21 January 2018

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Inhibition of glycosaminoglycan synthesis using rhodamine B in a mouse model of mucopolysaccharidosis type IIIA.

21 January 2018

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Improvement in behaviour after substrate deprivation therapy with rhodamine B in a mouse model of MPS IIIA.

21 January 2018

1 reference

Trans-generational exposure to low levels of rhodamine B does not adversely affect litter size or liver function in murine mucopolysaccharidosis type IIIA.

21 January 2018

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Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease

21 January 2018

1 reference

Gene silencing of EXTL2 and EXTL3 as a substrate deprivation therapy for heparan sulphate storing mucopolysaccharidoses.

21 January 2018

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Antisense oligonucleotide therapy for neurodegenerative disease.

21 January 2018

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Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides

21 January 2018

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Epidermal growth factor potentiates the induction of ornithine decarboxylase activity by prostaglandins in embryonic palate mesenchymal cells: effects on cell proliferation and glycosaminoglycan synthesis.

21 January 2018

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Concurrent measurement of unbound genistein in the blood, brain and bile of anesthetized rats using microdialysis and its pharmacokinetic application

21 January 2018

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Genistein-mediated inhibition of glycosaminoglycan synthesis as a basis for gene expression-targeted isoflavone therapy for mucopolysaccharidoses

21 January 2018

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Genistein-mediated inhibition of glycosaminoglycan synthesis, which corrects storage in cells of patients suffering from mucopolysaccharidoses, acts by influencing an epidermal growth factor-dependent pathway.

21 January 2018

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Storage correction in cells of patients suffering from mucopolysaccharidoses types IIIA and VII after treatment with genistein and other isoflavones

21 January 2018

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Effects of flavonoids on glycosaminoglycan synthesis: implications for substrate reduction therapy in Sanfilippo disease and other mucopolysaccharidoses

21 January 2018

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Genistein reduces glycosaminoglycan levels in a mouse model of mucopolysaccharidosis type II

21 January 2018

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Genistein reduces lysosomal storage in peripheral tissues of mucopolysaccharide IIIB mice

21 January 2018

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Genistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic disease

21 January 2018

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Substrate deprivation therapy: a new hope for patients suffering from neuronopathic forms of inherited lysosomal storage diseases

21 January 2018

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Genistin-rich soy isoflavone extract in substrate reduction therapy for Sanfilippo syndrome: An open-label, pilot study in 10 pediatric patients

21 January 2018

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Genistein supplementation in patients affected by Sanfilippo disease

21 January 2018

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Different amounts of isoflavones in various commercially available soy extracts in the light of gene expression-targeted isoflavone therapy

21 January 2018

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Genistein--a dietary compound inducing hormonal and metabolic changes

21 January 2018

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Genistein: a natural isoflavone with a potential for treatment of genetic diseases

21 January 2018

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Mechanisms of neurodegeneration in mucopolysaccharidoses II and IIIB: analysis of human brain tissue

21 January 2018

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Cytokines, neurotrophins, and oxidative stress in brain disease from mucopolysaccharidosis IIIB.

21 January 2018

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Mucopolysaccharidosis IIIB: oxidative damage and cytotoxic cell involvement in the neuronal pathogenesis.

21 January 2018

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Sanfilippo syndrome type B, a lysosomal storage disease, is also a tauopathy

21 January 2018

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Neuroprotective effect of genistein against beta amyloid-induced neurotoxicity

21 January 2018

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Genistein attenuates oxidative stress and neuronal damage following transient global cerebral ischemia in rat hippocampus.

21 January 2018

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Estradiol or genistein prevent Alzheimer's disease-associated inflammation correlating with an increase PPAR gamma expression in cultured astrocytes.

21 January 2018

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Genistein inhibits glutamate-induced apoptotic processes in primary neuronal cell cultures: an involvement of aryl hydrocarbon receptor and estrogen receptor/glycogen synthase kinase-3beta intracellular signaling pathway

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IUB.1007

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26 August 2017

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