(Q37995534)

26 August 2017

Eicosanoids and their drugs in cardiovascular diseases: focus on atherosclerosis and stroke (English)

1 reference

26 August 2017

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cardiovascular disease

1 reference

based on heuristic

inferred from title

author

Silvia Stella Barbieri

Silvia S Barbieri

3

0 references

Valérie Capra

Valérie Capra

1

0 references

Magnus Bäck

Magnus Bäck

2

0 references

Elena Tremoli

Elena Tremoli

5

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Marina Camera

4

Marina Camera

1 reference

26 August 2017

G Enrico Rovati

6

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26 August 2017

20 March 2012

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Medicinal Research Reviews

26 August 2017

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26 August 2017

33

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26 August 2017

2

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26 August 2017

364-438

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International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors

26 August 2017

1 reference

International Union of Pharmacology XLIV. Nomenclature for the oxoeicosanoid receptor

21 January 2018

1 reference

The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo

21 January 2018

1 reference

International Union of Basic and Clinical Pharmacology. LXXXIV: leukotriene receptor nomenclature, distribution, and pathophysiological functions

21 January 2018

1 reference

Detection and Isolation of an Endoperoxide Intermediate in Prostaglandin Biosynthesis

21 January 2018

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An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

21 January 2018

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Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides

21 January 2018

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Cyclooxygenases: structural, cellular, and molecular biology

21 January 2018

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Distinct functions of COX-1 and COX-2.

21 January 2018

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Leukotriene C: a slow-reacting substance from murine mastocytoma cells

21 January 2018

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Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

21 January 2018

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The discovery of the leukotrienes

21 January 2018

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Molecular cloning and amino acid sequence of human 5-lipoxygenase

21 January 2018

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Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

21 January 2018

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Biosynthesis and metabolism of leukotrienes

21 January 2018

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Molecular cloning and amino acid sequence of leukotriene A4 hydrolase

21 January 2018

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Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4

21 January 2018

1 reference

Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications

21 January 2018

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Arachidonic Acid metabolites in the cardiovascular system: the role of lipoxygenase isoforms in atherogenesis with particular emphasis on vascular remodeling

21 January 2018

1 reference

Functional and pathological roles of the 12- and 15-lipoxygenases

21 January 2018

1 reference

Redirection of prostaglandin endoperoxide metabolism at the platelet-vascular interface in man

21 January 2018

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Eicosanoid transcellular biosynthesis: from cell-cell interactions to in vivo tissue responses

21 January 2018

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Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes

21 January 2018

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Leukotrienes and lipoxins: structures, biosynthesis, and biological effects

21 January 2018

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Lipoxin biosynthesis and actions: role of the human platelet LX-synthase

21 January 2018

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Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions

21 January 2018

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Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways

21 January 2018

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Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

21 January 2018

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Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing

21 January 2018

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Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals

21 January 2018

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Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform

21 January 2018

1 reference

Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart

21 January 2018

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Epoxygenase pathways of arachidonic acid metabolism

21 January 2018

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Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid

21 January 2018

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Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids

21 January 2018

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Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels

21 January 2018

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Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells.

21 January 2018

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Activation of rat mesenteric arterial KATP channels by 11,12-epoxyeicosatrienoic acid

21 January 2018

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Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels

21 January 2018

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Epoxyeicosatrienoic acids and endothelium-dependent responses.

21 January 2018

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Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11

21 January 2018

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CYP4A mRNA, protein, and product in rat lungs: novel localization in vascular endothelium

21 January 2018

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Renal and cardiovascular actions of 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids

21 January 2018

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Isolated human and rat cerebral arteries constrict to increases in flow: role of 20-HETE and TP receptors

21 January 2018

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20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension

21 January 2018

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A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.

21 January 2018

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Formation of non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro

21 January 2018

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The isoprostanes: unique products of arachidonic acid oxidation-a review

21 January 2018

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Molecular pharmacology of isoprostanes in vascular smooth muscle

21 January 2018

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Thromboxane receptor blockade improves the antiatherogenic effect of thromboxane A2 suppression in LDLR KO mice

21 January 2018

1 reference

Improved endothelial function by the thromboxane A2 receptor antagonist S 18886 in patients with coronary artery disease treated with aspirin

21 January 2018

1 reference

Human biochemistry of the isoprostane pathway

21 January 2018

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Prostanoid receptor antagonists: development strategies and therapeutic applications

21 January 2018

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The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

21 January 2018

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Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation

21 January 2018

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Cloning and expression of cDNA for a human thromboxane A2 receptor

21 January 2018

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A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

21 January 2018

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Identification of a novel human eicosanoid receptor coupled to G(i/o)

21 January 2018

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Oligomerization of the alpha and beta isoforms of the thromboxane A2 receptor: relevance to receptor signaling and endocytosis

21 January 2018

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CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells

21 January 2018

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Regulation of thromboxane receptor trafficking through the prostacyclin receptor in vascular smooth muscle cells: role of receptor heterodimerization

21 January 2018

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Heterodimerization of the alpha and beta isoforms of the human thromboxane receptor enhances isoprostane signaling

21 January 2018

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Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversifies the complement of receptors

21 January 2018

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The quest for new cysteinyl-leukotriene and lipoxin receptors: recent clues

21 January 2018

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The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implications

21 January 2018

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Evidence for a second receptor for prostacyclin on human airway epithelial cells that mediates inhibition of CXCL9 and CXCL10 release.

21 January 2018

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Prostanoid receptors: subtypes and signaling

21 January 2018

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Structural organization of the human prostaglandin EP3 receptor subtype gene (PTGER3)

21 January 2018

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Cloning and expression of a cDNA for the human prostacyclin receptor.

21 January 2018

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Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets

21 January 2018

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A novel pathway of prostacyclin signaling-hanging out with nuclear receptors

21 January 2018

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Shear stress induces synthetic-to-contractile phenotypic modulation in smooth muscle cells via peroxisome proliferator-activated receptor alpha/delta activations by prostacyclin released by sheared endothelial cells

21 January 2018

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Human prostacyclin receptor

21 January 2018

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Human prostacyclin receptor structure and function from naturally-occurring and synthetic mutations

21 January 2018

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Thromboxane A2: physiology/pathophysiology, cellular signal transduction and pharmacology

21 January 2018

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Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells

21 January 2018

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Cyclooxygenase-2-derived prostaglandin F2alpha mediates endothelium-dependent contractions in the aortae of hamsters with increased impact during aging

21 January 2018

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G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets

21 January 2018

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Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation

21 January 2018

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Thromboxane A(2) receptors: where have you gone?

21 January 2018

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Dimerization of the human receptors for prostacyclin and thromboxane facilitates thromboxane receptor-mediated cAMP generation

21 January 2018

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The prostacyclin--thromboxane A2 balance: pathophysiological and therapeutic implications

21 January 2018

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Role of prostacyclin in the cardiovascular response to thromboxane A2

21 January 2018

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Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice

21 January 2018

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Prostacyclin receptor/thromboxane receptor interactions and cellular responses in human atherothrombotic disease

21 January 2018

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The thromboxane/endoperoxide receptor (TP): the common villain

21 January 2018

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Cell-specific transcriptional regulation of human leukotriene B(4) receptor gene

21 January 2018

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A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders

21 January 2018

1 reference

Cloning and characterization of cDNA encoding a novel human leukotriene B(4) receptor

21 January 2018

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A novel hepatointestinal leukotriene B4 receptor. Cloning and functional characterization

21 January 2018

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Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2

21 January 2018

1 reference

Involvement of the BLT2 receptor in the itch-associated scratching induced by 12-(S)-lipoxygenase products in ICR mice

21 January 2018

1 reference

12(S)-Hydroxyheptadeca-5Z, 8E, 10E-trienoic acid is a natural ligand for leukotriene B4 receptor 2

21 January 2018

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The PPARalpha-leukotriene B4 pathway to inflammation control.

21 January 2018

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Leukotriene B4 is a physiologically relevant endogenous peroxisome proliferator-activated receptor-alpha agonist

21 January 2018

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Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances

21 January 2018

1 reference

Novel compounds that interact with both leukotriene B4 receptors and vanilloid TRPV1 receptors.

21 January 2018

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Leukotriene receptors: crucial components in vascular inflammation.

21 January 2018

1 reference

Leukotriene B4: metabolism and signal transduction.

21 January 2018

1 reference

21 January 2018

Leukotriene B4 receptors

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Characterization of the human cysteinyl leukotriene CysLT1 receptor

21 January 2018

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Characterization of the human cysteinyl leukotriene 2 receptor

21 January 2018

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The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT(2) receptor

21 January 2018

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Cysteinyl-leukotriene receptors and cellular signals.

21 January 2018

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Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends.

21 January 2018

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Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor

21 January 2018

1 reference

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family

21 January 2018

1 reference

Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor

21 January 2018

1 reference

The human N-formylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors

21 January 2018

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Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor

21 January 2018

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Lipoxin A4 antagonizes cellular and in vivo actions of leukotriene D4 in rat glomerular mesangial cells: evidence for competition at a common receptor

21 January 2018

1 reference

Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses

21 January 2018

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Atherosclerosis — An Inflammatory Disease

21 January 2018

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21 January 2018

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27th Bethesda Conference: matching the intensity of risk factor management with the hazard for coronary disease events. Task Force 3. Spectrum of risk factors for coronary heart disease

21 January 2018

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Passive cigarette smoking increases isoprostane formation.

21 January 2018

1 reference

Urinary thromboxane, prostacyclin, cortisol, and 8-hydroxy-2'-deoxyguanosine in nonsmokers exposed and not exposed to environmental tobacco smoke

21 January 2018

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Cigarette smoking inhibits prostacyclin formation

21 January 2018

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Increase of isoprostane 8-epi-PGF(2alpha)after restarting smoking

21 January 2018

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Prostaglandins and lipid modification

21 January 2018

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Lipoprotein (a) and stroke

21 January 2018

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Lipoprotein(a): a causal independent risk factor for coronary heart disease?

21 January 2018

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Hypertension and cerebrovascular dysfunction

21 January 2018

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Endothelium-dependent contractions in hypertension

21 January 2018

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How a damaged blood vessel wall contibutes to thrombosis and hypertenasion

21 January 2018

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Cyclooxygenase 1-derived prostaglandin E2 and EP1 receptors are required for the cerebrovascular dysfunction induced by angiotensin II.

21 January 2018

1 reference

Endothelin-1 and F2-isoprostane relate to and predict renal dysfunction in hypertensive patients

21 January 2018

1 reference

Legacy effects from DCCT and UKPDS: what they mean and implications for future diabetes trials

21 January 2018

1 reference

Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications

21 January 2018

1 reference

Thromboxane biosynthesis and platelet function in type II diabetes mellitus

21 January 2018

1 reference

Thromboxane B2 formation and platelet sensitivity to prostacyclin in insulin-dependent and insulin-independent diabetics.

21 January 2018

1 reference

Platelet dysfunction in type 2 diabetes

21 January 2018

1 reference

Total and regional fat and serum cardiovascular disease risk factors in lean and obese children and adolescents

21 January 2018

1 reference

Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988-2000.

21 January 2018

1 reference

"Normal" blood glucose and coronary risk

21 January 2018

1 reference

Metabolic complications of obesity

21 January 2018

1 reference

The insulin resistance syndrome: implications for thrombosis and cardiovascular disease

21 January 2018

1 reference

Prostaglandins and obesity

21 January 2018

1 reference

Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study

21 January 2018

1 reference

Factors associated with oxidative stress in human populations

21 January 2018

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Platelet activation in obese women: role of inflammation and oxidant stress

21 January 2018

1 reference

Increased urinary leukotriene E4 excretion in obstructive sleep apnea: effects of obesity and hypoxia.

21 January 2018

1 reference

C-reactive protein and outcome after ischemic stroke

21 January 2018

1 reference

Predictive value of C-reactive protein and troponin T in patients with unstable angina: a comparative analysis. CAPTURE Investigators. Chimeric c7E3 AntiPlatelet Therapy in Unstable angina REfractory to standard treatment trial

21 January 2018

1 reference

C-reactive protein and angiographic coronary artery disease: independent and additive predictors of risk in subjects with angina

21 January 2018

1 reference

Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease

21 January 2018

1 reference

C-reactive protein impairs coronary arteriolar dilation to prostacyclin synthase activation: role of peroxynitrite

21 January 2018

1 reference

21 January 2018

1 reference

A prospective study of plasma fibrinogen levels and the risk of stroke among participants in the bezafibrate infarction prevention study

21 January 2018

1 reference

Measuring plasma fibrinogen to predict stroke and myocardial infarction: an update

21 January 2018

1 reference

The pathogenesis of coronary artery disease and the acute coronary syndromes (2).

21 January 2018

1 reference

The pathogenesis of coronary artery disease and the acute coronary syndromes (1).

21 January 2018

1 reference

Fibrinogen mediated activation of platelet aggregation and thromboxane A2 release: pathological implications in vascular disease

21 January 2018

1 reference

Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis

21 January 2018

1 reference

A Quantitative Assessment of Plasma Homocysteine as a Risk Factor for Vascular Disease

21 January 2018

1 reference

Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis

21 January 2018

1 reference

Homocysteine and other sulfhydryl compounds enhance the binding of lipoprotein(a) to fibrin: a potential biochemical link between thrombosis, atherogenesis, and sulfhydryl compound metabolism

21 January 2018

1 reference

Abnormally high thromboxane biosynthesis in homozygous homocystinuria. Evidence for platelet involvement and probucol-sensitive mechanism

21 January 2018

1 reference

Oxidative stress and platelet activation in homozygous homocystinuria

21 January 2018

1 reference

Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin

21 January 2018

1 reference

Prostanoid EP(1)- and TP-receptors involved in the contraction of human pulmonary veins

21 January 2018

1 reference

Prostacyclin in vascular diseases. - Recent insights and future perspectives -.

21 January 2018

1 reference

Prostanoids in health and disease

21 January 2018

1 reference

Increased Prostacyclin Biosynthesis in Patients with Severe Atherosclerosis and Platelet Activation

21 January 2018

1 reference

Endogenous biosynthesis of prostacyclin during cardiac catheterization and angiography in man.

21 January 2018

1 reference

Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2

21 January 2018

1 reference

Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

21 January 2018

1 reference

Roles of prostaglandin I(2) and thromboxane A(2) in cardiac ischemia-reperfusion injury: a study using mice lacking their respective receptors

21 January 2018

1 reference

COX-2-derived prostacyclin confers atheroprotection on female mice

21 January 2018

1 reference

Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition

21 January 2018

1 reference

Dominant negative actions of human prostacyclin receptor variant through dimerization: implications for cardiovascular disease

21 January 2018

1 reference

Thromboxane receptor density is increased in human cardiovascular disease with evidence for inhibition at therapeutic concentrations by the AT(1) receptor antagonist losartan

21 January 2018

1 reference

Activation of thromboxane receptor upregulates interleukin (IL)-1beta-induced VCAM-1 expression through JNK signaling.

21 January 2018

1 reference

Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke

21 January 2018

1 reference

Arg60 to Leu mutation of the human thromboxane A2 receptor in a dominantly inherited bleeding disorder

21 January 2018

1 reference

21 January 2018

Aspirin, 110 years later

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Prostanoid receptors in the human vascular wall.

21 January 2018

1 reference

Physiological regulation of prostaglandins in the kidney

21 January 2018

1 reference

Vascular wall-produced prostaglandin E2 exacerbates arterial thrombosis and atherothrombosis through platelet EP3 receptors

21 January 2018

1 reference

Cyclooxygenase-2 expression and inhibition in atherothrombosis

21 January 2018

1 reference

Deletion of microsomal prostaglandin E synthase-1 increases sensitivity to salt loading and angiotensin II infusion

21 January 2018

1 reference

Microsomal prostaglandin E synthase-1 deletion suppresses oxidative stress and angiotensin II-induced abdominal aortic aneurysm formation.

21 January 2018

1 reference

Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis.

21 January 2018

1 reference

Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury

21 January 2018

1 reference

Overexpression of COX-2, Prostaglandin E synthase-1 and prostaglandin E receptors in blood mononuclear cells and plaque of patients with carotid atherosclerosis: regulation by nuclear factor-kappaB.

21 January 2018

1 reference

PGE2 decreases reactivity of human platelets by activating EP2 and EP4

21 January 2018

1 reference

Selective activation of the prostaglandin E2 receptor subtype EP2 or EP4 leads to inhibition of platelet aggregation.

21 January 2018

1 reference

PGE(2) -EP(2) signalling in endothelium is activated by haemodynamic stress and induces cerebral aneurysm through an amplifying loop via NF-κB.

21 January 2018

1 reference

Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia.

21 January 2018

1 reference

Neuroprotection by the PGE2 EP2 receptor in permanent focal cerebral ischemia

21 January 2018

1 reference

Reduced acute brain injury in PGE2 EP3 receptor-deficient mice after cerebral ischemia.

21 January 2018

1 reference

The PGE2 EP2 receptor and its selective activation are beneficial against ischemic stroke.

21 January 2018

1 reference

Activation of IP and EP(3) receptors alters cAMP-dependent cell migration

21 January 2018

1 reference

Platelet prostanoid receptors

21 January 2018

1 reference

The role of prostanoid receptors in mediating the effects of PGE(2) on human platelet function.

21 January 2018

1 reference

Increased bleeding tendency and decreased susceptibility to thromboembolism in mice lacking the prostaglandin E receptor subtype EP(3).

21 January 2018

1 reference

Structure-activity relationship studies leading to the identification of (2E)-3-[l-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-lH-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041), a potent and selective prostanoid EP3 recep

21 January 2018

1 reference

A novel prostaglandin E receptor 4-associated protein participates in antiinflammatory signaling

21 January 2018

1 reference

Prostaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activation

21 January 2018

1 reference

Prostaglandin E2 modulates the functional responsiveness of human monocytes to chemokines

21 January 2018

1 reference

Targeting prostaglandin E2 receptors as an alternative strategy to block cyclooxygenase-2-dependent extracellular matrix-induced matrix metalloproteinase-9 expression by macrophages

21 January 2018

1 reference

Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis

21 January 2018

1 reference

Vasorelaxation induced by prostaglandin E2 in human pulmonary vein: role of the EP4 receptor subtype.

21 January 2018

1 reference

The prostaglandin E2 receptor EP4 is expressed by human platelets and potently inhibits platelet aggregation and thrombus formation

21 January 2018

1 reference

Human cyclooxygenase-2 cDNA

21 January 2018

1 reference

The coxibs, selective inhibitors of cyclooxygenase-2.

21 January 2018

1 reference

Nonsteroidal antiinflammatory drugs: past, present and future

21 January 2018

1 reference

Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities

21 January 2018

1 reference

Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population

21 January 2018

1 reference

Balancing prostanoid activity in the human vascular system

21 January 2018

1 reference

Coxibs and cardiovascular disease

21 January 2018

1 reference

Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial

21 January 2018

1 reference

Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison

21 January 2018

1 reference

Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease

21 January 2018

1 reference

Risk of hospitalization for myocardial infarction among users of rofecoxib, celecoxib, and other NSAIDs: a population-based case-control study

21 January 2018

1 reference

Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study

21 January 2018

1 reference

Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis

21 January 2018

1 reference

Risk of Death or Reinfarction Associated With the Use of Selective Cyclooxygenase-2 Inhibitors and Nonselective Nonsteroidal Antiinflammatory Drugs After Acute Myocardial Infarction

21 January 2018

1 reference

Increased mortality and cardiovascular morbidity associated with use of nonsteroidal anti-inflammatory drugs in chronic heart failure

21 January 2018

1 reference

Risk of myocardial infarction and death associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) among healthy individuals: a nationwide cohort study

21 January 2018

1 reference

Cardiovascular risks of nonsteroidal antiinflammatory drugs in patients after hospitalization for serious coronary heart disease

21 January 2018

1 reference

Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials

21 January 2018

1 reference

Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2.

21 January 2018

1 reference

Association of myocardial infarctions with COX-2 inhibition may be related to immunomodulation towards a Th1 response resulting in atheromatous plaque instability: an evidence-based interpretation

21 January 2018

1 reference

Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group

21 January 2018

1 reference

Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib

21 January 2018

1 reference

Marked interindividual variability in the response to selective inhibitors of cyclooxygenase-2.

21 January 2018

1 reference

Protective effect of the G-765C COX-2 polymorphism on subclinical atherosclerosis and inflammatory markers in asymptomatic subjects with cardiovascular risk factors.

21 January 2018

1 reference

The risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors does not vary with polymorphisms in two regions of the cyclo-oxygenase-2 gene

21 January 2018

1 reference

The COX-2 G/C -765 polymorphism may modulate the occurrence of cerebrovascular ischemia.

21 January 2018

1 reference

Polymorphisms of prostaglandin-endoperoxide synthase 2 gene, and prostaglandin-E receptor 2 gene, C-reactive protein concentrations and risk of atherothrombosis: a nested case-control approach

21 January 2018

1 reference

Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway.

21 January 2018

1 reference

Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs

21 January 2018

1 reference

Celecoxib inhibits 5-lipoxygenase

21 January 2018

1 reference

Aspirin-triggered, cyclooxygenase-2-dependent lipoxin synthesis modulates vascular tone

21 January 2018

1 reference

Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution

21 January 2018

1 reference

Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients

21 January 2018

1 reference

The synthesis of a novel thromboxane receptor antagonist 4(Z)-6-(2-o-chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl) hexenoic acid ICI 192605.

21 January 2018

1 reference

ONO NT-126 is a potent and selective thromboxane A2 antagonist in human astrocytoma cells.

21 January 2018

1 reference

Antiplatelet activity of the long-acting thromboxane receptor antagonist BMS 180,291 in monkeys

21 January 2018

1 reference

From the design to the clinical application of thromboxane modulators

21 January 2018

1 reference

A novel anti-asthmatic quinone derivative, AA-2414 with a potent antagonistic activity against a variety of spasmogenic prostanoids

21 January 2018

1 reference

Picotamide, an antithromboxane agent, inhibits the migration and proliferation of arterial myocytes

21 January 2018

1 reference

Role of thromboxane A2 synthetase inhibitors in the treatment of patients with bronchial asthma

21 January 2018

1 reference

Therapeutic potential of thromboxane inhibitors in asthma

21 January 2018

1 reference

Antithrombotic effects of S 18886, a novel orally active thromboxane A2 receptor antagonist

21 January 2018

1 reference

S18886, a selective TP receptor antagonist, inhibits development of atherosclerosis in rabbits

21 January 2018

1 reference

Atherosclerosis regression and TP receptor inhibition: effect of S18886 on plaque size and composition--a magnetic resonance imaging study

21 January 2018

1 reference

Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, prevents hypertensive vascular hypertrophy and fibrosis

21 January 2018

1 reference

Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, increases survival in stroke-prone rats by preventing systemic inflammation and endothelial dysfunction: comparison with aspirin and rosuvastatin

21 January 2018

1 reference

Cyclooxygenases, thromboxane, and atherosclerosis: plaque destabilization by cyclooxygenase-2 inhibition combined with thromboxane receptor antagonism.

21 January 2018

1 reference

Negative effects of rofecoxib treatment on cardiac function after ischemia-reperfusion injury in APOE3Leiden mice are prevented by combined treatment with thromboxane prostanoid-receptor antagonist S18886 (terutroban).

21 January 2018

1 reference

The selective TP receptor antagonist, S18886 (terutroban), attenuates renal damage in the double transgenic rat model of hypertension

21 January 2018

1 reference

Daily administration of the TP receptor antagonist terutroban improved endothelial function in high-cardiovascular-risk patients with atherosclerosis

21 January 2018

1 reference

Thromboxane Antagonism with terutroban in Peripheral Arterial Disease: the TAIPAD study

21 January 2018

1 reference

Effect of the thromboxane prostaglandin receptor antagonist terutroban on arterial thrombogenesis after repeated administration in patients treated for the prevention of ischemic stroke

21 January 2018

1 reference

Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double-blind, parallel-group trial

21 January 2018

1 reference

Antagonism of thromboxane receptors by diclofenac and lumiracoxib

21 January 2018

1 reference

Dual COXIB/TP antagonists: a possible new twist in NSAID pharmacology and cardiovascular risk

21 January 2018

1 reference

Prostacyclin therapies for the treatment of pulmonary arterial hypertension

21 January 2018

1 reference

Pulmonary arterial hypertension: the most devastating vascular complication of systemic sclerosis.

21 January 2018

1 reference

TRA-418, a thromboxane A2 receptor antagonist and prostacyclin receptor agonist, inhibits platelet-leukocyte interaction in human whole blood.

21 January 2018

1 reference

Effects of TRA‐418, a novel TP‐receptor antagonist, and IP‐receptor agonist, on human platelet activation and aggregation

21 January 2018

1 reference

Inhibitors of the microsomal prostaglandin E(2) synthase-1 as alternative to non steroidal anti-inflammatory drugs (NSAIDs)--a critical review

21 January 2018

1 reference

Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease

21 January 2018

1 reference

DG-041 inhibits the EP3 prostanoid receptor--a new target for inhibition of platelet function in atherothrombotic disease

21 January 2018

1 reference

5-Lipoxygenase-activating protein: a potential link between innate and adaptive immunity in atherosclerosis and adipose tissue inflammation

21 January 2018

1 reference

Leukotriene signaling in atherosclerosis and ischemia

21 January 2018

1 reference

The 5-lipoxygenase/leukotriene pathway in preclinical models of cardiovascular disease

21 January 2018

1 reference

Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice

21 January 2018

1 reference

Localization of atherosclerosis susceptibility loci to chromosomes 4 and 6 using the Ldlr knockout mouse model

21 January 2018

1 reference

Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia

21 January 2018

1 reference

Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis

21 January 2018

1 reference

Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis

21 January 2018

1 reference

The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

21 January 2018

1 reference

Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population

21 January 2018

1 reference

Leukotriene B4production in healthy subjects carrying variants of the arachidonate 5-lipoxygenase-activating protein gene associated with a risk of myocardial infarction

21 January 2018

1 reference

Associations of genetic polymorphisms of arachidonate 5-lipoxygenase-activating protein with risk of coronary artery disease in a European-American population

21 January 2018

1 reference

The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm.

21 January 2018

1 reference

Genetic and pharmacological inhibition of the 5-lipoxygenase/leukotriene pathway in atherosclerotic lesion development in ApoE deficient mice.

21 January 2018

1 reference

Inhibition of five lipoxygenase activating protein (FLAP) by MK-886 decreases atherosclerosis in apoE/LDLR-double knockout mice

21 January 2018

1 reference

Pharmacological inhibition of BLT1 diminishes early abdominal aneurysm formation

21 January 2018

1 reference

Differential inflammatory activity across human abdominal aortic aneurysms reveals neutrophil-derived leukotriene B4 as a major chemotactic factor released from the intraluminal thrombus.

21 January 2018

1 reference

Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm

21 January 2018

1 reference

Upregulation of the 5-lipoxygenase pathway in human aortic valves correlates with severity of stenosis and leads to leukotriene-induced effects on valvular myofibroblasts.

21 January 2018

1 reference

Aortic valve stenosis: an active atheroinflammatory process

21 January 2018

1 reference

Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice

21 January 2018

1 reference

Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability

21 January 2018

1 reference

Expanding expression of the 5-lipoxygenase/leukotriene B4 pathway in atherosclerotic lesions of diabetic patients promotes plaque instability.

21 January 2018

1 reference

Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia

21 January 2018

1 reference

A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction

21 January 2018

1 reference

Genetic variation in the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) is associated with myocardial infarction in the German population

21 January 2018

1 reference

Genetic variation in members of the leukotriene biosynthesis pathway confer an increased risk of ischemic stroke: a replication study in two independent populations

21 January 2018

1 reference

Role of leukotriene B4 receptors in the development of atherosclerosis: potential mechanisms

21 January 2018

1 reference

Mechanisms of leukotriene B4--triggered monocyte adhesion

21 January 2018

1 reference

Leukotriene B4 strongly increases monocyte chemoattractant protein-1 in human monocytes

21 January 2018

1 reference

Association between 5-lipoxygenase expression and plaque instability in humans

21 January 2018

1 reference

Matrix metalloproteinases in atherothrombosis.

21 January 2018

1 reference

Leukotriene receptor antagonism and the prevention of extracellular matrix degradation during atherosclerosis and in-stent stenosis

21 January 2018

1 reference

ALOX5AP variants are associated with in-stent restenosis after percutaneous coronary intervention

21 January 2018

1 reference

Leukotrienes and the cardiovascular system

21 January 2018

1 reference

Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast

21 January 2018

1 reference

Cysteinyl-leukotrienes in cerebrovascular disease: angels and demons?

21 January 2018

1 reference

Promotor polymorphisms in leukotriene C4 synthase and risk of ischemic cerebrovascular disease

21 January 2018

1 reference

Leukotriene C4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals

21 January 2018

1 reference

Genetic variation in the leukotriene pathway and carotid intima-media thickness: a 2-stage replication study

21 January 2018

1 reference

Novel mutations in leukotriene C4 synthase and risk of cardiovascular disease based on genotypes from 50,000 individuals

21 January 2018

1 reference

A role for inflammatory mediators in heterologous desensitization of CysLT1 receptor in human monocytes.

21 January 2018

1 reference

Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells

21 January 2018

1 reference

Identification of endogenous surrogate ligands for human P2Y12 receptors by in silico and in vitro methods

21 January 2018

1 reference

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

21 January 2018

1 reference

P2Y6 receptors require an intact cysteinyl leukotriene synthetic and signaling system to induce survival and activation of mast cells

21 January 2018

1 reference

CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors

21 January 2018

1 reference

Concentration-dependent noncysteinyl leukotriene type 1 receptor-mediated inhibitory activity of leukotriene receptor antagonists

21 January 2018

1 reference

Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses

21 January 2018

1 reference

Multidrug resistance protein-1 affects oxidative stress, endothelial dysfunction, and atherogenesis via leukotriene C4 export

21 January 2018

1 reference

Activation of CysLT receptors induces astrocyte proliferation and death after oxygen-glucose deprivation

21 January 2018

1 reference

Pharmacological characterization of the first potent and selective antagonist at the cysteinyl leukotriene 2 (CysLT(2)) receptor

21 January 2018

1 reference

Functional characterization of cysteinyl leukotriene CysLT(2) receptor on human coronary artery smooth muscle cells

21 January 2018

1 reference

Levels of cysteinyl leukotriene receptor mRNA in human peripheral leucocytes: significantly higher expression of cysteinyl leukotriene receptor 2 mRNA in eosinophils

21 January 2018

1 reference

Dominant expression of the CysLT2 receptor accounts for calcium signaling by cysteinyl leukotrienes in human umbilical vein endothelial cells

21 January 2018

1 reference

Differential leukotriene receptor expression and calcium responses in endothelial cells and macrophages indicate 5-lipoxygenase-dependent circuits of inflammation and atherogenesis.

21 January 2018

1 reference

Directed vascular expression of human cysteinyl leukotriene 2 receptor modulates endothelial permeability and systemic blood pressure

21 January 2018

1 reference

Cysteinyl leukotriene 2 receptor-mediated vascular permeability via transendothelial vesicle transport

21 January 2018

1 reference

Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice

21 January 2018

1 reference

Endothelial cysteinyl leukotriene 2 receptor expression mediates myocardial ischemia-reperfusion injury.

21 January 2018

1 reference

Synthesis of cysteinyl leukotrienes in human endothelial cells: subcellular localization and autocrine signaling through the CysLT2 receptor

21 January 2018

1 reference

Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells

21 January 2018

1 reference

Cerebral infarction. Evolution of histopathological changes after occlusion of a middle cerebral artery in primates.

21 January 2018

1 reference

Correlation between release of free arachidonic acid and prostaglandin formation in brain cortex and cerebellum

21 January 2018

1 reference

Cysteinyl-leukotriene levels in intracerebral hemorrhage: an edema-promoting factor?

21 January 2018

1 reference

Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2.

21 January 2018

1 reference

Leukotrienes in the rat central nervous system

21 January 2018

1 reference

Production of leukotrienes in a model of focal cerebral ischaemia in the rat

21 January 2018

1 reference

Spatio-temporal properties of 5-lipoxygenase expression and activation in the brain after focal cerebral ischemia in rats.

21 January 2018

1 reference

Synthesis of compounds with properties of leukotrienes C4 and D4 in gerbil brains after ischemia and reperfusion.

21 January 2018

1 reference

Brain eicosanoid levels in spontaneously hypertensive rats after ischemia with reperfusion: leukotriene C4 as a possible cause of cerebral edema

21 January 2018

1 reference

Leukotriene C4 and prostaglandin E2 activities in the serum and cerebrospinal fluid during acute cerebral ischemia.

21 January 2018

1 reference

Cerebral ischemia in 5-lipoxygenase knockout mice

21 January 2018

1 reference

Montelukast, a cysteinyl leukotriene receptor-1 antagonist, dose- and time-dependently protects against focal cerebral ischemia in mice

21 January 2018

1 reference

Pranlukast, a cysteinyl leukotriene receptor-1 antagonist, protects against chronic ischemic brain injury and inhibits the glial scar formation in mice

21 January 2018

1 reference

Pranlukast, a cysteinyl leukotriene receptor 1 antagonist, protects mice against brain cold injury.

21 January 2018

1 reference

Cysteinyl-leukotriene receptor antagonist montelukast decreases blood-brain barrier permeability but does not prevent oedema formation in traumatic brain injury.

21 January 2018

1 reference

Increased expression of cysteinyl leukotriene receptor-1 in the brain mediates neuronal damage and astrogliosis after focal cerebral ischemia in rats.

21 January 2018

1 reference

Spatio-temporal expression of cysteinyl leukotriene receptor-2 mRNA in rat brain after focal cerebral ischemia.

21 January 2018

1 reference

Distinct roles of CysLT1 and CysLT2 receptors in oxygen glucose deprivation-induced PC12 cell death

21 January 2018

1 reference

Leukotriene D4 induces brain edema and enhances CysLT2 receptor-mediated aquaporin 4 expression.

21 January 2018

1 reference

Functional characteristics of cysteinyl-leukotriene receptor subtypes.

21 January 2018

1 reference

Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors

21 January 2018

1 reference

A novel orphan G protein-coupled receptor primarily expressed in the brain is localized on human chromosomal band 2q21

21 January 2018

1 reference

GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4.

21 January 2018

1 reference

GPR17 regulates immune pulmonary inflammation induced by house dust mites

21 January 2018

1 reference

Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants.

21 January 2018

1 reference

The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair

21 January 2018

1 reference

The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury

21 January 2018

1 reference

Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation

21 January 2018

1 reference

The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination

21 January 2018

1 reference

Specific action of the lipoxygenase pathway in mediating angiotensin II-induced aldosterone synthesis in isolated adrenal glomerulosa cells

21 January 2018

1 reference

Role of the low-affinity leukotriene B4 receptor BLT2 in VEGF-induced angiogenesis

21 January 2018

1 reference

Lipoxygenase products increase monocyte adhesion to human aortic endothelial cells

21 January 2018

1 reference

Generation of unique mono-hydroxy-eicosatetraenoic acids from arachidonic acid by human neutrophils

21 January 2018

1 reference

Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages

21 January 2018

1 reference

15-Lipoxygenase-2 is expressed in macrophages in human carotid plaques and regulated by hypoxia-inducible factor-1alpha

21 January 2018

1 reference

The two faces of the 15-lipoxygenase in atherosclerosis

21 January 2018

1 reference

12/15-lipoxygenase, oxidative modification of LDL and atherogenesis

21 January 2018

1 reference

Fibroblasts that overexpress 15-lipoxygenase generate bioactive and minimally modified LDL.

21 January 2018

1 reference

Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein

21 January 2018

1 reference

Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidized low density lipoprotein

21 January 2018

1 reference

12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo

21 January 2018

1 reference

Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice

21 January 2018

1 reference

Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice

21 January 2018

1 reference

Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice

21 January 2018

1 reference

12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice

21 January 2018

1 reference

Transmembrane signaling in human polymorphonuclear neutrophils: 15(S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid modulates receptor agonist-triggered cell activation

21 January 2018

1 reference

Remodeling of neutrophil phospholipids with 15(S)-hydroxyeicosatetraenoic acid inhibits leukotriene B4-induced neutrophil migration across endothelium

21 January 2018

1 reference

Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development

21 January 2018

1 reference

Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators

21 January 2018

1 reference

Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators

21 January 2018

1 reference

Identification of the orphan G protein-coupled receptor GPR31 as a receptor for 12-(S)-hydroxyeicosatetraenoic acid

21 January 2018

1 reference

The immune response in atherosclerosis: a double-edged sword

21 January 2018

1 reference

Lipid mediator class switching during acute inflammation: signals in resolution.

21 January 2018

1 reference

Aspirin-triggered lipoxin and resolvin E1 modulate vascular smooth muscle phenotype and correlate with peripheral atherosclerosis

21 January 2018

1 reference

Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial

21 January 2018

1 reference

Synthesis of lipoxin A4 by 5-lipoxygenase mediates PPARgamma-dependent, neuroprotective effects of rosiglitazone in experimental stroke.

21 January 2018

1 reference

Atorvastatin-induced cardioprotection is mediated by increasing inducible nitric oxide synthase and consequent S-nitrosylation of cyclooxygenase-2.

21 January 2018

1 reference

Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4.

21 January 2018

1 reference

15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation

21 January 2018

1 reference

Aspirin augments 15-epi-lipoxin A4 production by lipopolysaccharide, but blocks the pioglitazone and atorvastatin induction of 15-epi-lipoxin A4 in the rat heart

21 January 2018

1 reference

Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins

21 January 2018

1 reference

Functional polymorphism in ALOX15 results in increased allele-specific transcription in macrophages through binding of the transcription factor SPI1.

21 January 2018

1 reference

A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease

21 January 2018

1 reference

Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1

21 January 2018

1 reference

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

21 January 2018

1 reference

Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation

21 January 2018

1 reference

Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione.

21 January 2018

1 reference

The mechanism of action of omega-3 fatty acids in secondary prevention post-myocardial infarction

21 January 2018

1 reference

Resolvin E1, an EPA-derived mediator in whole blood, selectively counterregulates leukocytes and platelets

21 January 2018

1 reference

Resolvin E1 regulates adenosine diphosphate activation of human platelets

21 January 2018

1 reference

Resolvin E1 protects the rat heart against reperfusion injury

21 January 2018

1 reference

Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression

21 January 2018

1 reference

Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation.

21 January 2018

1 reference

Cysteinyl-leukotriene receptor antagonists: present situation and future opportunities

21 January 2018

1 reference

Limitation of myocardial infarct size in pigs with a dual lipoxygenase-cyclooxygenase blocking agent by inhibition of neutrophil activity without reduction of neutrophil migration

21 January 2018

1 reference

Licofelone, a balanced inhibitor of cyclooxygenase and 5-lipoxygenase, reduces inflammation in a rabbit model of atherosclerosis.

21 January 2018

1 reference

Role of 5-lipoxygenase in myocardial ischemia-reperfusion injury in mice

21 January 2018

1 reference

The potential link between atherosclerosis and the 5-lipoxygenase pathway: investigational agents with new implications for the cardiovascular field

21 January 2018

1 reference

Effects of a 5-lipoxygenase-activating protein inhibitor on biomarkers associated with risk of myocardial infarction: a randomized trial

21 January 2018

1 reference

Treatment with 5-lipoxygenase inhibitor VIA-2291 (Atreleuton) in patients with recent acute coronary syndrome.

21 January 2018

1 reference

Anti-atherogenic effects of montelukast associated with reduced MCP-1 expression in a rabbit carotid balloon injury model

21 January 2018

1 reference

Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils.

21 January 2018

1 reference

Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors

21 January 2018

1 reference

Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo

21 January 2018

1 reference

Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration

21 January 2018

1 reference

Lipoxin A4 stable analogs inhibit leukocyte rolling and adherence in the rat mesenteric microvasculature: role of P-selectin.

21 January 2018

1 reference

Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion

21 January 2018

1 reference

A novel peptide agonist of formyl-peptide receptor-like 1 (ALX) displays anti-inflammatory and cardioprotective effects

21 January 2018

1 reference

Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor

21 January 2018

1 reference

Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action.

21 January 2018

1 reference

Are formyl peptide receptors novel targets for therapeutic intervention in ischaemia-reperfusion injury?

21 January 2018

1 reference

Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells

21 January 2018

1 reference

Novel lipid mediator regulators of endothelial cell proliferation and migration: aspirin-triggered-15R-lipoxin A(4) and lipoxin A(4).

21 January 2018

1 reference

Mediators of bradykinin-induced vasorelaxation in human coronary microarteries

21 January 2018

1 reference

K+ is an endothelium-derived hyperpolarizing factor in rat arteries.

21 January 2018

1 reference

Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice

21 January 2018

1 reference

Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor

21 January 2018

1 reference

Role of arachidonic acid lipoxygenase metabolites in the regulation of vascular tone

21 January 2018

1 reference

Baseline blood flow and bradykinin-induced vasodilator responses in the human forearm are insensitive to the cytochrome P450 2C9 (CYP2C9) inhibitor sulphaphenazole

21 January 2018

1 reference

Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans

21 January 2018

1 reference

Role of cytochrome P-450 arachidonate metabolites in endothelin signaling in rat proximal tubule

21 January 2018

1 reference

20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids and blood pressure

21 January 2018

1 reference

Evidence that 20-HETE contributes to the development of acute and delayed cerebral vasospasm

21 January 2018

1 reference

Cerebrospinal fluid 20-HETE is associated with delayed cerebral ischemia and poor outcomes after aneurysmal subarachnoid hemorrhage

21 January 2018

1 reference

Elevated production of 20-HETE in the cerebral vasculature contributes to severity of ischemic stroke and oxidative stress in spontaneously hypertensive rats.

21 January 2018

1 reference

Beneficial effects of a new 20-hydroxyeicosatetraenoic acid synthesis inhibitor, TS-011 [N-(3-chloro-4-morpholin-4-yl) phenyl-N'-hydroxyimido formamide], on hemorrhagic and ischemic stroke

21 January 2018

1 reference

Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia

21 January 2018

1 reference

Effect of a new inhibitor of the synthesis of 20-HETE on cerebral ischemia reperfusion injury.

21 January 2018

1 reference

Continuous inhibition of 20-HETE synthesis by TS-011 improves neurological and functional outcomes after transient focal cerebral ischemia in rats

21 January 2018

1 reference

Effect of 20-HETE inhibition on infarct volume and cerebral blood flow after transient middle cerebral artery occlusion

21 January 2018

1 reference

The inhibitor of 20-HETE synthesis, TS-011, improves cerebral microcirculatory autoregulation impaired by middle cerebral artery occlusion in mice

21 January 2018

1 reference

CYP4F2 gene V433M polymorphism is associated with ischemic stroke in the male Northern Chinese Han population

21 January 2018

1 reference

A haplotype of the CYP4F2 gene is associated with cerebral infarction in Japanese men.

21 January 2018

1 reference

Haplotype-based case study of human CYP4A11 gene and cerebral infarction in Japanese subject

21 January 2018

1 reference

The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure

21 January 2018

1 reference

Regulation and inhibition of arachidonic acid omega-hydroxylases and 20-HETE formation

21 January 2018

1 reference

Isoprostanes: formation, analysis and use as indices of lipid peroxidation in vivo

21 January 2018

1 reference

The isoprostanes - unique products of arachidonate peroxidation: their role as mediators of oxidant stress

21 January 2018

1 reference

Isoprostanes: potential markers of oxidant stress in atherothrombotic disease

21 January 2018

1 reference

Recent advances in the biochemistry and clinical relevance of the isoprostane pathway

21 January 2018

1 reference

Prostanoid and isoprostanoid pathways in atherogenesis

21 January 2018

1 reference

Vascular biology of eicosanoids and atherogenesis

21 January 2018

1 reference

Localization of distinct F2-isoprostanes in human atherosclerotic lesions

21 January 2018

1 reference

Lipid peroxidation in mouse models of atherosclerosis

21 January 2018

1 reference

Angioplasty increases coronary sinus F2-isoprostane formation: evidence for in vivo oxidative stress during PTCA

21 January 2018

1 reference

Low-density lipoprotein level reduction by the 3-hydroxy-3-methylglutaryl coenzyme-A inhibitor simvastatin is accompanied by a related reduction of F2-isoprostane formation in hypercholesterolemic subjects: no further effect of vitamin E.

21 January 2018

1 reference

Vitamin E reduces progression of atherosclerosis in low-density lipoprotein receptor-deficient mice with established vascular lesions

21 January 2018

1 reference

Urinary 8-iso-prostaglandin F2alpha as a risk marker in patients with coronary heart disease: a matched case-control study

21 January 2018

1 reference

Associations of plasma 8-isoprostane levels with the presence and extent of coronary stenosis in patients with coronary artery disease.

21 January 2018

1 reference

The relationship of hydroxyeicosatetraenoic acids and F2-isoprostanes to plaque instability in human carotid atherosclerosis

21 January 2018

1 reference

Oxidative stress-induced isoprostane formation may contribute to aspirin resistance in platelets

21 January 2018

1 reference

Characterization of the effects of isoprostanes on platelet aggregation in human whole blood

21 January 2018

1 reference

Thromboxane, prostacyclin and isoprostanes: therapeutic targets in atherogenesis

21 January 2018

1 reference

Vasoconstriction induced by activation of EP1 and EP3 receptors in human lung: effects of ONO-AE-248, ONO-DI-004, ONO-8711 or ONO-8713.

21 January 2018

1 reference

Cyclooxygenase 2 is a key enzyme for inflammatory cytokine-induced angiogenesis

21 January 2018

1 reference

Prostaglandin E2 receptors in abdominal aortic aneurysm and human aortic smooth muscle cells

21 January 2018

1 reference

Prostanoid receptors involved in the relaxation of human pulmonary vessels

21 January 2018

1 reference

Differential effects of stable prostacyclin analogs on smooth muscle proliferation and cyclic AMP generation in human pulmonary artery

21 January 2018

1 reference

Gene expression profile of the Gs-coupled prostacyclin receptor in human vascular smooth muscle cells

21 January 2018

1 reference

Different pharmacologic activities for 13-azapinane thromboxane A2 analogs in platelets and blood vessels

21 January 2018

1 reference

Thromboxane A(2) receptor mediated activation of the mitogen activated protein kinase cascades in human uterine smooth muscle cells

21 January 2018

1 reference

The contractile action of leukotriene B4 in the guinea-pig lung involves a vascular component.

21 January 2018

1 reference

Characterization of cysteinyl leukotriene receptors on human saphenous veins: antagonist activity of montelukast and its metabolites.

21 January 2018

1 reference

CysLT1 signal transduction in differentiated U937 cells involves the activation of the small GTP-binding protein Ras.

21 January 2018

1 reference

CysLT1 receptor is a target for extracellular nucleotide-induced heterologous desensitization: a possible feedback mechanism in inflammation.

21 January 2018

1 reference

Function of prostanoid receptors: studies on knockout mice

21 January 2018

1 reference

Roles of prostanoids in the pathogenesis of cardiovascular diseases: Novel insights from knockout mouse studies

21 January 2018

1 reference

Targeted disruption of the leukotriene B(4) receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis

21 January 2018

1 reference

Nationwide cohort study of the leukotriene receptor antagonist montelukast and incident or recurrent cardiovascular disease

21 January 2018

1 reference

PLATELET THROMBOXANES AND SERUM-CHOLESTEROL

21 January 2018

1 reference

C-Reactive Protein, Interleukin-6, and Soluble Adhesion Molecules as Predictors of Progressive Peripheral Atherosclerosis in the General Population

21 January 2018

1 reference

Angiotensin II Modulates Ion Transport in Rat Proximal Tubules through CYP Metabolites

21 January 2018

1 reference

Prostacyclin inhibits mobilisation of fibrinogen-binding sites on human ADP- and thrombin-treated platelets

21 January 2018

1 reference

Prevalence and trends in overweight among US children and adolescents, 1999-2000

21 January 2018

1 reference

28 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1001/JAMA.288.14.1728

Identifiers

DOI

10.1002/MED.21251

1 reference

26 August 2017

1 reference

PubMed ID

22434418