(Q37997073)

26 August 2017

title

Tec family kinases in inflammation and disease (English)

1 reference

26 August 2017

Nicole J Horwood

1

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26 August 2017

Ania M Urbaniak

series ordinal

2

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26 August 2017

Lynett Danks

series ordinal

3

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26 August 2017

publication date

1 April 2012

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International Reviews of Immunology

26 August 2017

published in

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26 August 2017

volume

31

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26 August 2017

issue

2

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26 August 2017

page(s)

87-103

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Elevated cytokine production restores bone resorption by human Btk-deficient osteoclasts.

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bruton's tyrosine kinase (Btk)-the critical tyrosine kinase in LPS signalling?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bmx regulates LPS-induced IL-6 and VEGF production via mRNA stability in rheumatoid synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

B cell signaling and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

The role of Tec family kinases in mononuclear phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Harmful molecular mechanisms in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

B cells and macrophages in cancer: yin and yang.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Signaling pathways downstream of pattern-recognition receptors and their cross talk

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Src tyrosine kinases mediate activations of NF-kappaB and integrin signal during lipopolysaccharide-induced acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and Lyn

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Hck tyrosine kinase regulates TLR4-induced TNF and IL-6 production via AP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

A novel spleen tyrosine kinase inhibitor blocks c-Jun N-terminal kinase-mediated gene expression in synoviocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bruton's tyrosine kinase is a key regulator in B-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Initiation and processing of signals from the B cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Regulation of BCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Akt signaling: linking membrane events to life and death decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Regulation of B-cell activation and differentiation by the phosphatidylinositol 3-kinase and phospholipase Cgamma pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Btk function in B cell development and response.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

SHIP modulates immune receptor responses by regulating membrane association of Btk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcgammaRIIb, which are modulated by anti-tumor necrosis factor therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Fcgamma receptors as regulators of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Unimpaired activation of c-Jun NH2-terminal kinase (JNK) 1 upon CD40 stimulation in B cells of patients with X-linked agammaglobulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Syk mediates BCR- and CD40-signaling integration during B cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Reconstitution of Btk signaling by the atypical tec family tyrosine kinases Bmx and Txk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

B cells and osteoblast and osteoclast development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

How B cells influence bone biology in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Osteoimmunology: interactions of the bone and immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Development and function of murine B cells lacking RANK.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

The tec family tyrosine kinase Btk Regulates RANKL-induced osteoclast maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

The macrophage: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Macrophages as APC and the dendritic cell myth

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Critical roles of the WASP N-terminal domain and Btk in LPS-induced inflammatory response in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bruton's tyrosine kinase together with PI 3-kinase are part of Toll-like receptor 2 multiprotein complex and mediate LTA induced Toll-like receptor 2 responses in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

NF-kappaB RelA phosphorylation regulates RelA acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bruton's tyrosine kinase phosphorylates cAMP-responsive element-binding protein at serine 133 during neuronal differentiation in immortalized hippocampal progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Different roles for non-receptor tyrosine kinases in arachidonate release induced by zymosan and Staphylococcus aureus in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Defects in acute responses to TLR4 in Btk-deficient mice result in impaired dendritic cell-induced IFN-γ production by natural killer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bruton's tyrosine kinase is required for TLR-dependent heme oxygenase-1 gene activation via Nrf2 in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

TLR signaling and effector functions are intact in XLA neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Fatal disseminated mouse adenovirus type 1 infection in mice lacking B cells or Bruton's tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Toll-like receptor signaling is impaired in dendritic cells from patients with X-linked agammaglobulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

MHC class II molecules enhance Toll-like receptor mediated innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Activation of MyD88 signaling upon staphylococcal enterotoxin binding to MHC class II molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Btk is a positive regulator in the TREM-1/DAP12 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Bmx tyrosine kinase is specifically expressed in the endocardium and the endothelium of large arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Etk/BMX, a Btk family tyrosine kinase, and Mal contribute to the cross-talk between MyD88 and FAK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

The tyrosine kinase BMX is an essential mediator of inflammatory arthritis in a kinase-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Treatment of rheumatoid arthritis: state of the art 2009.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Prospective new biological therapies for rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Efficacy and safety of pamapimod in patients with active rheumatoid arthritis receiving stable methotrexate therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Evaluation of the efficacy and safety of pamapimod, a p38 MAP kinase inhibitor, in a double-blind, methotrexate-controlled study of patients with active rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: results of two randomized, double-blind, placebo-controlled clinical studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

"Go upstream, young man": lessons learned from the p38 saga

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

An oral Syk kinase inhibitor in the treatment of rheumatoid arthritis: a three-month randomized, placebo-controlled, phase II study in patients with active rheumatoid arthritis that did not respond to biologic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

An oral spleen tyrosine kinase (Syk) inhibitor for rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Inhibition of JAK kinases in patients with rheumatoid arthritis: scientific rationale and clinical outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

New drugs beyond biologics in rheumatoid arthritis: the kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Imatinib and beyond--exploring the full potential of targeted therapy for CML.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Imatinib mesylate inhibited rat adjuvant arthritis and PDGF-dependent growth of synovial fibroblast via interference with the Akt signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Inhibition of fms-like tyrosine kinase 3 alleviates experimental arthritis by reducing formation of dendritic cells and antigen presentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Profound inhibition of antigen-specific T-cell effector functions by dasatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (d

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Dasatinib is a potent inhibitor of tumour-associated macrophages, osteoclasts and the FMS receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Antiarthritis effect of a novel Bruton's tyrosine kinase (BTK) inhibitor in rat collagen-induced arthritis and mechanism-based pharmacokinetic/pharmacodynamic modeling: relationships between inhibition of BTK phosphorylation and efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830185.2012.670334

10.3109/08830185.2012.670334

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference