(Q35187075)

7 August 2017

OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice (English)

1 reference

osteoclast differentiation

7 August 2017

1 reference

Fc receptor, IgE, high affinity I, gamma polypeptide

1 reference

Tumor necrosis factor (ligand) superfamily, member 11

1 reference

Osteoclast associated receptor

1 reference

Triggering receptor expressed on myeloid cells 2

1 reference

Transforming growth factor, beta 1

1 reference

TYRO protein tyrosine kinase binding protein

1 reference

author

Alexander D Barrow

Alexander David Barrow

1

0 references

Nicholas Pugh

Nicholas Pugh

6

0 references

Thomas L Andersen

Thomas Levin Andersen

3

0 references

Marina Cella

Marina Cella

7

0 references

Marco Colonna

Marco Colonna

14

0 references

Richard W Farndale

15

Richard W Farndale

1 reference

7 August 2017

5

Dominique Bihan

1 reference

7 August 2017

2

Nicolas Raynal

1 reference

7 August 2017

4

David A Slatter

1 reference

7 August 2017

17

John Trowsdale

1 reference

7 August 2017

Taesoo Kim

8

1 reference

7 August 2017

Jaerang Rho

9

1 reference

7 August 2017

Takako Negishi-Koga

10

1 reference

7 August 2017

Jean-Marie Delaisse

11

1 reference

7 August 2017

Hiroshi Takayanagi

12

1 reference

7 August 2017

Joseph Lorenzo

13

1 reference

7 August 2017

Yongwon Choi

16

1 reference

7 August 2017

language of work or name

English

0 references

publication date

15 August 2011

1 reference

Journal of Clinical Investigation

7 August 2017

1 reference

7 August 2017

121

1 reference

7 August 2017

3505-3516

1 reference

7 August 2017

9

1 reference

Paired immunoglobin-like receptor-B regulates the suppressive function and fate of myeloid-derived suppressor cells

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Alternative activation of macrophages: mechanism and functions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Development of monocytes, macrophages, and dendritic cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Matrix crosslinking forces tumor progression by enhancing integrin signaling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Ca2+-NFATc1 signaling is an essential axis of osteoclast differentiation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Inhibitory regulation of osteoclast bone resorption by signal regulatory protein alpha.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Cross-regulation of signaling by ITAM-associated receptors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

A physical mechanism for coupling bone resorption and formation in adult human bone.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Essential role of DAP12 signaling in macrophage programming into a fusion-competent state

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Inhibitory immunoglobulin-like receptors LILRB and PIR-B negatively regulate osteoclast development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

The extended human leukocyte receptor complex: diverse ways of modulating immune responses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

DAP12 couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Siglec-15: an immune system Siglec conserved throughout vertebrate evolution

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

PLCgamma2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Remodeling and vascular spaces in bone

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

You say ITAM and I say ITIM, let's call the whole thing off: the ambiguity of immunoreceptor signalling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Use of synthetic peptides to locate novel integrin alpha2beta1-binding motifs in human collagen III.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Association of the OSCAR promoter polymorphism with BMD in postmenopausal women

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

The genetic causes of basal ganglia calcification, dementia, and bone cysts: DAP12 and TREM2.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Paracrine regulation of osteoclast formation and activity: milestones in discovery.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

OSCAR is an FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Cutting edge: TREM-like transcript-1, a platelet immunoreceptor tyrosine-based inhibition motif encoding costimulatory immunoreceptor that enhances, rather than inhibits, calcium signaling via SHP-2

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

The role of collagen in thrombosis and hemostasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Collagens—structure, function, and biosynthesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Impaired differentiation of osteoclasts in TREM-2-deficient individuals

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Heterogeneity of presenile dementia with bone cysts (Nasu-Hakola disease): three genetic forms.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

A novel member of the leukocyte receptor complex regulates osteoclast differentiation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

TREM-1 amplifies inflammation and is a crucial mediator of septic shock

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Bone resorption by osteoclasts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

A molecular analysis of NKT cells: identification of a class-I restricted T cell-associated molecule (CRTAM)

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Characterization of endosteal bone-lining cells from fatty marrow bone sites in adult beagles.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

The bone lining cell: a distinct phenotype?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Bone marrow monocyte PECAM-1 deficiency elicits increased osteoclastogenesis resulting in trabecular bone loss.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Induction of osteoclast-associated receptor, a key osteoclast costimulation molecule, in rheumatoid arthritis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Characterization of high affinity binding motifs for the discoidin domain receptor DDR2 in collagen

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163954

Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesis

27 September 2018

1 reference

12 December 2020

Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers

1 reference

12 December 2020

The role of mesenchyme in embryonic long bones as early deposition site for osteoclast progenitor cells

1 reference

12 December 2020

An assessment of the prevalence of organic material on bone surfaces

1 reference

12 December 2020

Human microvascular endothelial cell activation by IL-1 and TNF-alpha stimulates the adhesion and transendothelial migration of circulating human CD14+ monocytes that develop with RANKL into functional osteoclasts

1 reference

12 December 2020

v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation

1 reference

12 December 2020

Multinucleate giant cells release functionally unopposed matrix metalloproteinase-9 in vitro and in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI45913

1 reference

7 August 2017

1 reference

7 August 2017

1 reference