(Q37999058)

26 August 2017

Novel models for assessing blood-brain barrier drug permeation (English)

1 reference

26 August 2017

1 reference

Werner J Geldenhuys

1

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26 August 2017

David D Allen

series ordinal

2

1 reference

26 August 2017

Jeffrey R Bloomquist

series ordinal

3

1 reference

26 August 2017

language of work or name

English

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publication date

3 April 2012

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Expert Opinion on Drug Metabolism & Toxicology

26 August 2017

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26 August 2017

8

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26 August 2017

6

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26 August 2017

647-653

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Blood-brain barrier delivery

26 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Modelling of the blood-brain barrier in drug discovery and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

The ABC of the blood-brain barrier - regulation of drug efflux pumps

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

ADMET in silico modelling: towards prediction paradise?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Preclinical pharmacokinetics: an approach towards safer and efficacious drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Chemical modification of paclitaxel (Taxol) reduces P-glycoprotein interactions and increases permeation across the blood-brain barrier in vitro and in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Drug repurposing and adverse event prediction using high-throughput literature analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

The price of innovation: new estimates of drug development costs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

The cost of drug development: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Drug screening--beyond the bottleneck

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

In silico prediction of blood–brain barrier permeation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Multi-step usage of in vivo models during rational drug design and discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Current concepts of blood-brain barrier development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Structure and function of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Dynamics of CNS barriers: evolution, differentiation, and modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Junctions between intimately apposed cell membranes in the vertebrate brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Development of the blood-brain barrier: a historical point of view

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Drug delivery to the posterior segment of the eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

The blood-retinal barrier: structure and functional significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Assays to predict drug permeation across the blood-brain barrier, and distribution to brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Transporter-mediated drug uptake and efflux: important determinants of adverse drug reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Biopharmaceutical drug targeting to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Regulation of ABC transporters at the blood-brain barrier: new targets for CNS therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Structure and function of the human breast cancer resistance protein (BCRP/ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Chronic exposure to nicotine and saquinavir decreases endothelial Notch-4 expression and disrupts blood-brain barrier integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Nicotine and cotinine increases the brain penetration of saquinavir in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Brain-targeted delivery of paclitaxel using glutathione-coated nanoparticles for brain cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Brain-targeted delivery of Tempol-loaded nanoparticles for neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Physiologic and anatomic characterization of the brain surface glia barrier of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

The functional organisation of glia in the adult brain of Drosophila and other insects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Models for predicting blood-brain barrier permeation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Invertebrate animal models of diseases as screening tools in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Neuron-glial interactions in blood-brain barrier formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

The molecular physiology of tight junction pores

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

High-throughput screening and small animal models, where are we?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Organization and function of the blood-brain barrier in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

New animal models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrier permeability in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Novel models for studying the blood-brain and blood-eye barriers in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

A high-content screening assay in transgenic zebrafish identifies two novel activators of fgf signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Behavioral screening for neuroactive drugs in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Drug screening in a zebrafish model of Duchenne muscular dystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Identification of novel inhibitors of dietary lipid absorption using zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

The developing zebrafish (Danio rerio): a vertebrate model for high-throughput screening of chemical libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Functional and developmental analysis of the blood-brain barrier in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

Blood barriers of the insect

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.677433

10.1517/17425255.2012.677433

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference