(Q38001796)

English

Evaluation of 5-fluorouracil pharmacokinetics in cancer patients with a c.1905+1G>A mutation in DPYD by means of a Bayesian limited sampling strategy

scientific article published on October 2012

In more languages

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

Evaluation of 5-fluorouracil pharmacokinetics in cancer patients with a c.1905+1G>A mutation in DPYD by means of a Bayesian limited sampling strategy (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

pharmacokinetics

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

André B P van Kuilenburg

1

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

Peter Häusler

2

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

Andreas Schalhorn

3

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

Michael W T Tanck

4

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

Johannes H Proost

5

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

Christoph Terborg

6

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

Detlev Behnke

7

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

Wolfgang Schwabe

8

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

Kati Jabschinsky

9

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

Jan Gerard Maring

10

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

publication date

1 March 2012

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

51

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

3

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

163-174

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

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1 reference

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Non-malignant fibrosing tumors in the pediatric hand: a clinicopathologic case review

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacokinetic analysis of 5-fluorouracil and its major metabolite 5-fluoro-5,6-dihydrouracil after conventional and reduced test dose in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between single nucleotide polymorphisms and haplotypes in DPYD and toxicity and efficacy of capecitabine in advanced colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limited sampling model for the analysis of 5-fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and inexpensive method for anticipating severe toxicity to fluorouracil and fluorouracil-based chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced 5-FU clearance in a patient with low DPD activity due to heterozygosity for a mutant allele of the DPYD gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of bolus 5-fluorouracil: relationship between dose, plasma concentrations, area-under-the-curve and toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic and demographic markers of 5-fluorouracil toxicity in 181 patients on adjuvant therapy for colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose and time dependencies of 5-fluorouracil pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Routine dihydropyrimidine dehydrogenase testing for anticipating 5-fluorouracil-related severe toxicities: hype or hope?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical relevance of different dihydropyrimidine dehydrogenase gene single nucleotide polymorphisms on 5-fluorouracil tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A point mutation in an invariant splice donor site leads to exon skipping in two unrelated Dutch patients with dihydropyrimidine dehydrogenase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Known variant DPYD alleles do not explain DPD deficiency in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of 5-fluorouracil in patients heterozygous for the IVS14+1G > A mutation in the dihydropyrimidine dehydrogenase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capecitabine as adjuvant treatment for stage III colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple and sensitive fully validated HPLC-UV method for the determination of 5-fluorouracil and its metabolite 5,6-dihydrofluorouracil in plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid identification of dihydropyrimidine dehydrogenase deficiency by using a novel 2-13C-uracil breath test

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population study of dihydropyrimidine dehydrogenase in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Understanding diagnostic tests 3: Receiver operating characteristic curves

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5'-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)- related toxicity compared with controls.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intragenic deletions and a deep intronic mutation affecting pre-mRNA splicing in the dihydropyrimidine dehydrogenase gene as novel mechanisms causing 5-fluorouracil toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydropyrimidine dehydrogenase deficiency and fluorouracil-related toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased risk of grade IV neutropenia after administration of 5-fluorouracil due to a dihydropyrimidine dehydrogenase deficiency: high prevalence of the IVS14+1g>a mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetics: from bench to byte--an update of guidelines

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening for dihydropyrimidine dehydrogenase deficiency: to do or not to do, that's the question

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydropyrimidine dehydrogenase and the efficacy and toxicity of 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implications of dihydropyrimidine dehydrogenase on 5-fluorouracil pharmacogenetics and pharmacogenomics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extensive hepatic replacement due to liver metastases has no effect on 5-fluorouracil pharmacokinetics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Performance of an iterative two-stage bayesian technique for population pharmacokinetic analysis of rich data sets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose monitoring of 5-fluorouracil in patients with colorectal or head and neck cancer--status of the art.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Fluorouracil-related severe toxicity: a comparison of different methods for the pretherapeutic detection of dihydropyrimidine dehydrogenase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Should DPD analysis be required prior to prescribing fluoropyrimidines?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New limited sampling strategy for determining 5-fluorouracil area under the concentration-time curve after rapid intravenous bolus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic therapy for colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of orally administered uracil in healthy volunteers and in DPD-deficient patients, a possible tool for screening of DPD deficiency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339448

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/11595880-000000000-00000

1 reference

https://api.fatcat.wiki/v0/release/k7r6nz23sfdc3e2vkiybnuhbgy

30 July 2022

based on heuristic

mapped directly with Wikidata item

Dimensions Publication ID

0 references

release_k7r6nz23sfdc3e2vkiybnuhbgy

1 reference

https://api.fatcat.wiki/v0/release/k7r6nz23sfdc3e2vkiybnuhbgy

30 July 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 April 2018

http://europepmc.org/abstract/MED/22339448

reason for deprecated rank

incorrect identifier value

0 references

1 reference

https://api.fatcat.wiki/v0/release/k7r6nz23sfdc3e2vkiybnuhbgy

30 July 2022

based on heuristic

mapped directly with Wikidata item

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q38001796&oldid=2201158635"