(Q38003481)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Assaying embryotoxicity in the test tube: current limitations of the embryonic stem cell test (EST) challenging its applicability domain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

6

Andreas Luch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Katrin Hayess

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Annelieke K Peters

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Margino Steemans

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Horst Spielmann

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Andrea E M Seiler

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

1 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

Critical Reviews in Toxicology

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

443-464

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22512667%20AND%20SRC:MED&resulttype=core&format=json

Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity

29 January 2020

cites work

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Retinoic acid-mediated differentiation protects against nitrofen-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

In vitro developmental toxicology assays: A review of the state of the science of rodent and zebrafish whole embryo culture and embryonic stem cell assays

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Identification of diphenhydramine metabolites in human urine by capillary electrophoresis-ion trap-mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Early cerebrovascular and parenchymal events following prenatal exposure to the putative neurotoxin methylazoxymethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Different effect of methylazoxymethanol on mouse cerebellar development depending on the age of injection.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Metabolism of Papaverine II. Species Differences

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Metabolism of Papaverine I. Identification of Metabolites in Rat Bile

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The vitamin K-dependent carboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Cation-chloride cotransporters and neuronal function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Mercury exposure and children's health

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Bendectin and birth defects: hopefully, the final chapter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Bendectin: review of the medical literature of a comprehensively studied human nonteratogen and the most prevalent tortogen-litigen

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Novel therapeutic approaches to the treatment of Wilson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Transport of inorganic mercury and methylmercury in target tissues and organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Improving stable transfection efficiency: antioxidants dramatically improve the outgrowth of clones under dominant marker selection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Embryonic stem cell test remastered: comparison between the validated EST and the new molecular FACS-EST for assessing developmental toxicity in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Interpretation of skeletal variations for human risk assessment: delayed ossification and wavy ribs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Production of lovastatin by Aspergillus terreus: effects of the C:N ratio and the principal nutrients on growth and metabolite production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Dopamine receptor subtypes in the native human heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Modelling of the blood-brain barrier in drug discovery and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Periostin, a member of a novel family of vitamin K-dependent proteins, is expressed by mesenchymal stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Hoechst tests lead EPA to ban herbicide.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Structure of the human histamine H1 receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Relative developmental toxicity of glycol ether alkoxy acid metabolites in the embryonic stem cell test as compared with the in vivo potency of their parent compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The Cantrell-sequence: a result of maternal exposure to aminopropionitriles?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

5-HT4 and 5-HT2 receptors antagonistically influence gap junctional coupling between rat auricular myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The gastroprokinetic and antiemetic drug metoclopramide is a substrate and inhibitor of cytochrome P450 2D6.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Metabolism, variability and risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

A review on ochratoxin A occurrence and effects of processing of cereal and cereal derived food products.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Retinoic acid synthesis and signaling during early organogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The gastrointestinal prokinetic benzamide derivatives are agonists at the non-classical 5-HT receptor (5-HT4) positively coupled to adenylate cyclase in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The many faces of methylmercury poisoning

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Parental epilepsy, anticonvulsant drugs, and reproductive outcome: epidemiologic and experimental findings spanning three decades; 1: Animal studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Generalized growth retardation in rats induced by prenatal exposure to methylazoxymethyl acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Mercury and monomethylmercury: present and future concerns

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

A cluster of sulfatase genes on Xp22.3: mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Current and future therapeutic prokinetic therapy to improve enteral feed intolerance in the ICU patient

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Maternal fumonisin exposure as a risk factor for neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Teratogenicity of dinoseb: role of the diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Use of antihistamine medications during early pregnancy and isolated major malformations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Current treatments and novel pharmacologic treatments for hyponatremia in congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Regulation of the mevalonate pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Effects of prenatal vitamins A, E, and C on the hypoplastic hearts of fetal rats with diaphragmatic hernia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Baseline serum folate level may be a predictive factor of weight loss in a morbid-obesity-management programme.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Pluripotent stem cell derived hepatocyte like cells and their potential in toxicity screening

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Recent advances in understanding the pathogenesis of nitrofen-induced congenital diaphragmatic hernia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Protein biomarkers for in vitro testing of embryotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Maternal and fetal sequelae of anticoagulation during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The biosynthesis of papaverine proceeds via (S)-reticuline

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Methanol, formaldehyde, and sodium formate exposure in rat and mouse conceptuses: a potential role of the visceral yolk sac in embryotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Perspectives on the use of the baboon in embryology and teratology research

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Metabolic activation capacity by primary hepatocytes expands the applicability of the embryonic stem cell test as alternative to experimental animal testing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Benefits and risks of furosemide in acute kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Animal testing and alternative approaches for the human health risk assessment under the proposed new European chemicals regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Lysyl oxidase is required for vascular and diaphragmatic development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Exposure of the pregnant rat to warfarin and vitamin K1: an animal model of intraventricular hemorrhage in the fetus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Recent advancements in the biosynthetic mechanisms for polyketide-derived mycotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Nitrofen: A review and perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

21 January 2018

Treatment of cystinuria

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

D-penicillamine pharmacokinetics and pharmacodynamics in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Histamine, histamine receptors and their role in immune pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Distinct pattern of neuronal degeneration in the fetal rat brain induced by consecutive transplacental administration of methylmercury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Human P450 metabolism of warfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Prevention of ochratoxin A-induced neural tube defects by folic acid in the genetic polydactyly/arhinencephaly mouse, Pdn/Pdn.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Vitamin A deficiency (VAD), teratogenic, and surgical models of congenital diaphragmatic hernia (CDH).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Effect of D-penicillamine on rat lung elastin cross-linking during the perinatal period

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Mechanisms of Disease: the kidney-specific chloride channels ClCKA and ClCKB, the Barttin subunit, and their clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Potassium-transporting proteins in skeletal muscle: cellular location and fibre-type differences.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Proline-rich Gla protein 2 is a cell-surface vitamin K-dependent protein that binds to the transcriptional coactivator Yes-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Neural tube closure defects caused by papaverine in explanted early chick embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Maternal and fetal toxicity of methylmercuric chloride administered to pregnant Fischer 344 rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Identification of the gene for vitamin K epoxide reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Mechanism of the peroxidase activity of Cu, Zn superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Synaptic cysteine sulfhydryl groups as targets of electrophilic neurotoxicants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Cytogenetic damage induced by folate deficiency in mice is enhanced by caffeine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Mechanism of nitrofen teratogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

3-hydroxy 3-methylglutaryl coenzyme A reductase increase is essential for rat muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The safety of metoclopramide use in the first trimester of pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Prenatal developmental toxicity of gavage or feeding doses of 2-sec-butyl-4,6-dinitrophenol in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Review of developmental toxicity of nitrophenolic herbicide dinoseb, 2-sec-butyl-4,6-dinitrophenol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

In vivo, in vitro and in silico methods for small molecule transfer across the BBB.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Retinal dehydrogenase-2 is inhibited by compounds that induce congenital diaphragmatic hernias in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

A suspension induction for myocardial differentiation of rat mesenchymal stem cells on various extracellular matrix proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca(2+) channels in the embryonic heart of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Structural and functional diversity of lysyl oxidase and the LOX-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Maternal exposure to diphenhydramine during the fetal period in rats: effects on physical and neurobehavioral development and on neurochemical parameters.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Action of papaverine and ionophore A23187 on neurulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Cycasin and its mutagenic metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Ochratoxin A induces craniofacial malformation in mice acting on Dlx5 gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Methylmercury and nutrition: adult effects of fetal exposure in experimental models

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Ochratoxin A: the continuing enigma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Assessment of the Embryonic Stem Cell Test and application and use in the pharmaceutical industry

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The sulfatase gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary dysplasia, lung hypoplasia, and mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Critical period and minimum single oral dose of ochratoxin A for inducing developmental toxicity in pregnant Wistar rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The test chemical selection procedure of the European Centre for the Validation of Alternative Methods for the EU Project ReProTect

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Evaluation of the embryotoxic potency of compounds in a newly revised high throughput embryonic stem cell test

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Automated analysis of contractility in the embryonic stem cell test, a novel approach to assess embryotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Ochratoxin A and aristolochic acid involvement in nephropathies and associated urothelial tract tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Infant with severe penicillamine embryopathy born to a woman with Wilson disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Effects in mice of high and low environmental temperature on the maternal and fetal toxicity of 2-sec-butyl-4,6-dinitrophenol (dinoseb) and on disposition of [14C]-dinoseb

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Aneurysmal subarachnoid haemorrhage and the anaesthetist

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The embryonic stem cell test as tool to assess structure-dependent teratogenicity: the case of valproic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Defined culture medium for stem cell differentiation: applicability of serum-free conditions in the mouse embryonic stem cell test.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Toxicokinetics and toxicodynamics of ochratoxin A, an update

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

A journey through mitogen-activated protein kinase and ochratoxin A interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Retrospective study on temporal and regional variations of methylmercury concentrations in preserved umbilical cords collected from inhabitants of the Minamata area, Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Translating 5-HT receptor pharmacology.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Cloning and characterization of a putative human holocytochrome c-type synthetase gene (HCCS) isolated from the critical region for microphthalmia with linear skin defects (MLS)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The ReProTect Feasibility Study, a novel comprehensive in vitro approach to detect reproductive toxicants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Significance of protein binding in pharmacokinetics and pharmacodynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Cycads: their evolution, toxins, herbivores and insect pollinators.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Prevalidation of the Embryonic Stem Cell Test (EST)-A New In Vitro Embryotoxicity Test

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Improvement of an in vitro stem cell assay for developmental toxicity: the use of molecular endpoints in the embryonic stem cell test

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The validated embryonic stem cell test to predict embryotoxicity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Classic histamine H1 receptor antagonists: a critical review of their metabolic and pharmacokinetic fate from a bird's eye view

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Chemical and biological properties of toxic metals and use of chelating agents for the pharmacological treatment of metal poisoning.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Inhibition of the striatum-enriched phosphodiesterase PDE10A: a novel approach to the treatment of psychosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Over-the-counter cold medications. A critical review of clinical trials between 1950 and 1991.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Embryotoxicity hazard assessment of methylmercury and chromium using embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Cardiotoxic potential and CNS effects of first-generation antihistamines.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Prenatal exposure to HMG-CoA reductase inhibitors: effects on fetal and neonatal outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Uncompensated polyuria in a mouse model of Bartter's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Dithiothreitol prevents age-associated decrease in oocyte/conceptus viability in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

An abbreviated protocol for multilineage neural differentiation of murine embryonic stem cells and its perturbation by methyl mercury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Review article: clinical implications of enteric and central D2 receptor blockade by antidopaminergic gastrointestinal prokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Monooxygenases as biocatalysts: Classification, mechanistic aspects and biotechnological applications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Developmental toxicity evaluation of Bendectin in CD rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

ReProGlo: a new stem cell-based reporter assay aimed to predict embryotoxic potential of drugs and chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Mercury in the Aquatic Environment: A Review of Factors Affecting Methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Localization and targeting of voltage-dependent ion channels in mammalian central neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Monitoring developmental toxicity in the embryonic stem cell test using differential gene expression of differentiation-related genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Optimization of chemically defined cell culture media--replacing fetal bovine serum in mammalian in vitro methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Teratogen update: fetal effects after in utero exposure to coumarins overview of cases, follow-up findings, and pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Toxic actions of dinoseb in medaka (Oryzias latipes) embryos as determined by in vivo 31P NMR, HPLC-UV and 1H NMR metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Extrapolation of animal toxicity to humans: interspecies comparisons in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Warfarin and the vitamin K-dependent gamma-carboxylation system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

The story of the discovery of heparin and warfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Characteristics of growth and palatal shelf development in ICR mice after exposure to methylmercury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Comparing three novel endpoints for developmental osteotoxicity in the embryonic stem cell test

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Neurobehavioral effects of developmental methylmercury exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Potential human developmental toxicants and the role of animal testing in their identification and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483

Predictive value of animal models for human cytochrome P450 (CYP)-mediated metabolism: A comparative studyin vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408444.2012.674483