(Q38017601)

27 August 2017

title

Stromal biomarkers in breast cancer development and progression (English)

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27 August 2017

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Charlotte Kuperwasser

series ordinal

2

object named as

Charlotte Kuperwasser

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27 August 2017

Jenny A Rudnick

1

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27 August 2017

publication date

10 June 2012

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Clinical & Experimental Metastasis

27 August 2017

published in

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27 August 2017

volume

29

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27 August 2017

issue

7

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27 August 2017

page(s)

663-672

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https://scigraph.springernature.com/pub.10.1007/s10585-012-9499-8

27 August 2017

exact match

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cites work

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Deficiency in the LIM-only protein Fhl2 impairs skin wound healing

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Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer

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Stromal gene expression predicts clinical outcome in breast cancer

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Gene expression profiling of the tumor microenvironment during breast cancer progression

21 January 2018

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

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Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.

21 January 2018

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Cancer-associated stromal fibroblasts promote pancreatic tumor progression

21 January 2018

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VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization

21 January 2018

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Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner.

21 January 2018

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Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells

21 January 2018

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The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers

21 January 2018

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Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Fibroblast activation protein-α promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Loss of stromal caveolin-1 expression predicts poor clinical outcome in triple negative and basal-like breast cancers

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers

21 January 2018

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Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis

21 January 2018

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Expression of tenascin-C and its isoforms in the breast

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Epithelial cells are an important source of tenascin in normal and malignant human breast tissue

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Human Carcinoma Cells Synthesize and Secrete Tenascin in vitro

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and growth by matrix metalloproteinase-dependent and independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Co-expression of tenascin-C and vimentin in human breast cancer cells indicates phenotypic transdifferentiation during tumour progression: correlation with histopathological parameters, hormone receptors, and oncoproteins

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Tenascin-C expression in invasion border of early breast cancer: a predictor of local and distant recurrence

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Expression of extracellular matrix components versican, chondroitin sulfate, tenascin, and hyaluronan, and their association with disease outcome in node-negative breast cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Lung metastasis genes couple breast tumor size and metastatic spread.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Genes that mediate breast cancer metastasis to lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Helicobacter pylori and gastric cancer: a new paradigm for inflammation-associated epithelial cancers.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Promotion of colorectal neoplasia in experimental murine ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Tumour-infiltrating macrophages and clinical outcome in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

The prognostic significance of B lymphocytes in invasive carcinoma of the breast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Leukocyte composition of human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Angiogenesis and inflammation in invasive carcinoma of the breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Macrophages regulate the angiogenic switch in a mouse model of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Stromal MCP-1 in mammary tumors induces tumor-associated macrophage infiltration and contributes to tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Expression of CD68 in non-myeloid cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Cyclooxygenase-2 as a target for anticancer drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Prostaglandins and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Elevated expression of cyclooxygenase-2 is a negative prognostic factor for disease free survival and overall survival in patients with breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

COX-2 expression is associated with an aggressive phenotype in ductal carcinoma in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Analysis of cyclooxygenase-2 expression in human breast cancer: high throughput tissue microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Prognostic impact of cyclooxygenase-2 in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

COX-2 expression in DCIS: correlation with VEGF, HER-2/neu, prognostic molecular markers and clinicopathological features.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Biomarker expression and risk of subsequent tumors after initial ductal carcinoma in situ diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

p16(INK4a) expression and breast cancer risk in women with atypical hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Decreased TGFbeta signaling and increased COX2 expression in high risk women with increased mammographic breast density

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Regulation of in situ to invasive breast carcinoma transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

More than structural cells, fibroblasts create and orchestrate the tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

A tense situation: forcing tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Balancing forces: architectural control of mechanotransduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Tensional homeostasis and the malignant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Cell tension, matrix mechanics, and cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Collagen density promotes mammary tumor initiation and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Reconstruction of functionally normal and malignant human breast tissues in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Matrix crosslinking forces tumor progression by enhancing integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Distinct epigenetic changes in the stromal cells of breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Specific protein and miRNA patterns characterise tumour-associated fibroblasts in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Stromal fibroblasts in cancer: a novel tumor-promoting cell type

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Global hypomethylation of genomic DNA in cancer-associated myofibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Tissue repair, contraction, and the myofibroblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

The origin of fibroblasts and mechanism of cardiac fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Methylation determines fibroblast activation and fibrogenesis in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Enhanced hepatocyte growth factor signaling by type II transforming growth factor-beta receptor knockout fibroblasts promotes mammary tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Pten in stromal fibroblasts suppresses mammary epithelial tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

MicroRNA: basic mechanisms and transcriptional regulatory networks for cell fate determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

MicroRNAs: key regulators of stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Function and localization of microRNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

MicroRNAs in embryonic stem cell function and fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

MicroRNA in Cancer: The Involvement of Aberrant MicroRNA Biogenesis Regulatory Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

MicroRNA sequence and expression analysis in breast tumors by deep sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

MicroRNA gene expression deregulation in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

MicroRNA-21: from cancer to cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

SMAD proteins control DROSHA-mediated microRNA maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Micro-RNA-21 regulates TGF-β-induced myofibroblast differentiation by targeting PDCD4 in tumor-stroma interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

MicroRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Effective immunoconjugate therapy in cancer models targeting a serine protease of tumor fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Clonal Mutations in the Cancer-Associated Fibroblasts: The Case against Genetic Coevolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10585-012-9499-8

Differential distribution of tenascin in the normal, hyperplastic, and neoplastic breast

21 January 2018

1 reference

12 December 2020

Deficiency of tenascin C attenuates allergen-induced bronchial asthma in the mouse

1 reference

12 December 2020

Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

1 reference

12 December 2020

Lysyl oxidase-like protein localizes to sites of de novo fibrinogenesis in fibrosis and in the early stromal reaction of ductal breast carcinomas.

1 reference

12 December 2020

Differentially expressed genes associated with the metastatic phenotype in breast cancer

1 reference

12 December 2020

The impact of caveolin protein expression in tumor stroma on prognosis of breast cancer

1 reference

12 December 2020

Expression of tenascin in invasion border of early breast cancer correlates with higher risk of distant metastasis

1 reference

12 December 2020

Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma

1 reference

12 December 2020

High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-beta1

1 reference

12 December 2020

Induction of alpha-smooth muscle actin by transforming growth factor-beta 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia

1 reference

12 December 2020

Expression and targeting of human fibroblast activation protein in a human skin/severe combined immunodeficient mouse breast cancer xenograft model

1 reference

12 December 2020

Expression of tenascin-C in intraductal carcinoma of human breast: relationship to invasion

1 reference

12 December 2020

Lysyl oxidase gene expression in the stromal reaction to in situ and invasive ductal breast carcinoma

1 reference

12 December 2020

Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow

1 reference

12 December 2020

Lymphoid infiltration as a prognostic variable for early-onset breast carcinomas

1 reference

12 December 2020

Macrophage infiltration and its prognostic implications in breast cancer: the relationship with VEGF expression and microvessel density

1 reference

12 December 2020

Microvessel density, VEGF expression, and tumor-associated macrophages in breast tumors: correlations with prognostic parameters.

1 reference

12 December 2020

10.1007/S10585-012-9499-8

Identifiers

DOI

1 reference

Dimensions Publication ID

27 August 2017

1036382754

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1 reference