(Q38018005)

27 August 2017

Recent approaches to the prioritization of candidate disease genes (English)

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27 August 2017

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2

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PubMed ID

22689539

Nadezhda Tsankova Doncheva

27 August 2017

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1

object named as

Nadezhda T Doncheva

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author name string

Mario Albrecht

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3

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27 August 2017

11 June 2012

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Wiley interdisciplinary reviews. Systems biology and medicine

27 August 2017

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27 August 2017

4

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27 August 2017

5

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27 August 2017

429-442

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Genetics of Crohn disease, an archetypal inflammatory barrier disease

27 August 2017

1 reference

Genome-wide association studies: results from the first few years and potential implications for clinical medicine

21 January 2018

1 reference

Mapping rare and common causal alleles for complex human diseases

21 January 2018

1 reference

Human genetic variation and its contribution to complex traits

21 January 2018

1 reference

The genetics of quantitative traits: challenges and prospects

21 January 2018

1 reference

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

21 January 2018

1 reference

Genomewide association studies and assessment of the risk of disease

21 January 2018

1 reference

The art and design of genetic screens: RNA interference.

21 January 2018

1 reference

Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

21 January 2018

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Translational disease interpretation with molecular networks.

21 January 2018

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Advances in translational bioinformatics: computational approaches for the hunting of disease genes

21 January 2018

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Linking genes to diseases: it's all in the data.

21 January 2018

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A guide to web tools to prioritize candidate genes

21 January 2018

1 reference

Network medicine: a network-based approach to human disease

21 January 2018

1 reference

Interactome networks and human disease

21 January 2018

1 reference

Network-based methods for human disease gene prediction

21 January 2018

1 reference

Computational approaches to disease-gene prediction: rationale, classification and successes.

21 January 2018

1 reference

21 January 2018

1 reference

POCUS: mining genomic sequence annotation to predict disease genes

21 January 2018

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SUSPECTS: enabling fast and effective prioritization of positional candidates

21 January 2018

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Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genes

21 January 2018

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Identification of candidate disease genes by integrating Gene Ontologies and protein-interaction networks: case study of primary immunodeficiencies.

21 January 2018

1 reference

Improving disease gene prioritization using the semantic similarity of Gene Ontology terms

21 January 2018

1 reference

Novel search method for the discovery of functional relationships

21 January 2018

1 reference

Protein interactions and disease: computational approaches to uncover the etiology of diseases.

21 January 2018

1 reference

Protein networks in disease

21 January 2018

1 reference

The human disease network

21 January 2018

1 reference

Molecular triangulation: bridging linkage and molecular-network information for identifying candidate genes in Alzheimer's disease.

21 January 2018

1 reference

A network-based method for predicting disease-causing genes.

21 January 2018

1 reference

Predicting disease genes using protein-protein interactions.

21 January 2018

1 reference

Discovering disease-genes by topological features in human protein-protein interaction network.

21 January 2018

1 reference

A human phenome-interactome network of protein complexes implicated in genetic disorders

21 January 2018

1 reference

Combining the interactome and deleterious SNP predictions to improve disease gene identification.

21 January 2018

1 reference

Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis

21 January 2018

1 reference

Network modeling links breast cancer susceptibility and centrosome dysfunction

21 January 2018

1 reference

Predicting Type 1 Diabetes Candidate Genes using Human Protein-Protein Interaction Networks

21 January 2018

1 reference

Walking the interactome for prioritization of candidate disease genes

21 January 2018

1 reference

Disease candidate gene identification and prioritization using protein interaction networks

21 January 2018

1 reference

eQED: an efficient method for interpreting eQTL associations using protein networks

21 January 2018

1 reference

Identifying disease-specific genes based on their topological significance in protein networks

21 January 2018

1 reference

The power of protein interaction networks for associating genes with diseases

21 January 2018

1 reference

DADA: Degree-Aware Algorithms for Network-Based Disease Gene Prioritization

21 January 2018

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Network-based global inference of human disease genes

21 January 2018

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Genome-wide inferring gene-phenotype relationship by walking on the heterogeneous network.

21 January 2018

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Modularity-based credible prediction of disease genes and detection of disease subtypes on the phenotype-gene heterogeneous network.

21 January 2018

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Uncover disease genes by maximizing information flow in the phenome-interactome network

21 January 2018

1 reference

A computational method based on the integration of heterogeneous networks for predicting disease-gene associations

21 January 2018

1 reference

PhenomeNET: a whole-phenome approach to disease gene discovery

21 January 2018

1 reference

Associating genes and protein complexes with disease via network propagation

21 January 2018

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Inferring gene-phenotype associations via global protein complex network propagation

21 January 2018

1 reference

Inferring disease and gene set associations with rank coherence in networks

21 January 2018

1 reference

Gene prioritization through genomic data fusion

21 January 2018

1 reference

Integration of multiple data sources to prioritize candidate genes using discounted rating system

21 January 2018

1 reference

Improved human disease candidate gene prioritization using mouse phenotype

21 January 2018

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Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes

21 January 2018

1 reference

In silico gene prioritization by integrating multiple data sources

21 January 2018

1 reference

Kernel-based data fusion for gene prioritization

21 January 2018

1 reference

An integrated approach to inferring gene-disease associations in humans

21 January 2018

1 reference

A machine learning approach for genome-wide prediction of morbid and druggable human genes based on systems-level data.

21 January 2018

1 reference

ProDiGe: Prioritization Of Disease Genes with multitask machine learning from positive and unlabeled examples

21 January 2018

1 reference

Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network

21 January 2018

1 reference

Exploring the human genome with functional maps

21 January 2018

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Prioritizing candidate disease genes by network-based boosting of genome-wide association data.

21 January 2018

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BioGraph: unsupervised biomedical knowledge discovery via automated hypothesis generation

21 January 2018

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Using bioinformatics to predict the functional impact of SNVs

21 January 2018

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Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data

21 January 2018

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Bioinformatics challenges for personalized medicine

21 January 2018

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Phylomedicine: an evolutionary telescope to explore and diagnose the universe of disease mutations

21 January 2018

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In silico SNP analysis and bioinformatics tools: a review of the state of the art to aid drug discovery

21 January 2018

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Genome-wide identification of genes likely to be involved in human genetic disease

21 January 2018

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Speeding disease gene discovery by sequence based candidate prioritization

21 January 2018

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Further understanding human disease genes by comparing with housekeeping genes and other genes

21 January 2018

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Understanding and using the medical subject headings (MeSH) vocabulary to perform literature searches

21 January 2018

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Gene ontology: tool for the unification of biology

21 January 2018

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PSICQUIC and PSISCORE: accessing and scoring molecular interactions

21 January 2018

1 reference

Global topological features of cancer proteins in the human interactome

21 January 2018

1 reference

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration

21 January 2018

1 reference

Network properties of genes harboring inherited disease mutations

21 January 2018

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Assessing experimentally derived interactions in a small world

21 January 2018

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Authoritative sources in a hyperlinked environment

21 January 2018

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An integrative genomics approach to infer causal associations between gene expression and disease

21 January 2018

1 reference

Variations in DNA elucidate molecular networks that cause disease

21 January 2018

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Finding biologically accurate clusterings in hierarchical tree decompositions using the variation of information.

21 January 2018

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Computational analysis of human protein interaction networks.

21 January 2018

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Literature-curated protein interaction datasets.

21 January 2018

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The commonality of protein interaction networks determined in neurodegenerative disorders (NDDs).

21 January 2018

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The modular nature of genetic diseases.

21 January 2018

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McKusick's Online Mendelian Inheritance in Man (OMIM)

21 January 2018

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ENDEAVOUR update: a web resource for gene prioritization in multiple species

21 January 2018

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Large-scale benchmark of Endeavour using MetaCore maps

21 January 2018

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KEGG: kyoto encyclopedia of genes and genomes

21 January 2018

1 reference

BIND--The Biomolecular Interaction Network Database

21 January 2018

1 reference

Human Protein Reference Database--2009 update

21 January 2018

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Reactome: a knowledgebase of biological pathways

21 January 2018

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An empirical framework for binary interactome mapping

21 January 2018

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Towards completion of the Earth's proteome

21 January 2018

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Integrating multiple protein-protein interaction networks to prioritize disease genes: a Bayesian regression approach

21 January 2018

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Comparison of vocabularies, representations and ranking algorithms for gene prioritization by text mining.

21 January 2018

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DomainRBF: a Bayesian regression approach to the prioritization of candidate domains for complex diseases.

21 January 2018

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Genomic gene clustering analysis of pathways in eukaryotes

21 January 2018

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Align human interactome with phenome to identify causative genes and networks underlying disease families.

21 January 2018

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Network analysis of differential expression for the identification of disease-causing genes

21 January 2018

1 reference

Candidate gene prioritization by network analysis of differential expression using machine learning approaches.

21 January 2018

1 reference

Identifying causal genes and dysregulated pathways in complex diseases

21 January 2018

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21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/WSBM.1177

1 reference

27 August 2017

1 reference

PubMed ID

22689539