(Q38018190)

27 August 2017

title

Phosphoproteomics and molecular cardiology: techniques, applications and challenges (English)

1 reference

27 August 2017

Kenneth F Reardon

3

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author name string

Zeyu Sun

series ordinal

1

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27 August 2017

Karyn L Hamilton

series ordinal

2

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27 August 2017

publication date

9 June 2012

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Journal of Molecular and Cellular Cardiology

27 August 2017

published in

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27 August 2017

volume

53

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27 August 2017

issue

3

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27 August 2017

page(s)

354-368

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Phosphoprotein analysis using antibodies broadly reactive against phosphorylated motifs

27 August 2017

cites work

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Evaluation of the utility of neutral-loss-dependent MS3 strategies in large-scale phosphorylation analysis

7 January 2021

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Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Revealing the dynamics of the 20 S proteasome phosphoproteome: a combined CID and electron transfer dissociation approach

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

7 January 2021

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Supplemental activation method for high-efficiency electron-transfer dissociation of doubly protonated peptide precursors

7 January 2021

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In-depth analysis of tandem mass spectrometry data from disparate instrument types

7 January 2021

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PEAKS: powerful software for peptide de novo sequencing by tandem mass spectrometry

7 January 2021

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Better score function for peptide identification with ETD MS/MS spectra

7 January 2021

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A probability-based approach for high-throughput protein phosphorylation analysis and site localization

7 January 2021

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7 January 2021

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PhosphoScore: an open-source phosphorylation site assignment tool for MSn data

7 January 2021

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Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentation

7 January 2021

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An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets

7 January 2021

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Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

7 January 2021

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7 January 2021

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KinasePhos: a web tool for identifying protein kinase-specific phosphorylation sites

7 January 2021

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Proteomic analysis of pharmacologically preconditioned cardiomyocytes reveals novel phosphorylation of myosin light chain 1

7 January 2021

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Phosphoproteome analysis of cardiomyocytes subjected to beta-adrenergic stimulation: identification and characterization of a cardiac heat shock protein p20.

7 January 2021

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Phosphoproteome analysis of isoflurane-protected heart mitochondria: phosphorylation of adenine nucleotide translocator-1 on Tyr194 regulates mitochondrial function.

7 January 2021

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Quantitative comparison of sarcomeric phosphoproteomes of neonatal and adult rat hearts

7 January 2021

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7 January 2021

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Metabolic labeling of mammalian organisms with stable isotopes for quantitative proteomic analysis

7 January 2021

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7 January 2021

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Amino acid residue specific stable isotope labeling for quantitative proteomics

7 January 2021

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A proteomic approach for quantitation of phosphorylation using stable isotope labeling in cell culture

7 January 2021

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Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics

7 January 2021

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Dissection of the insulin signaling pathway via quantitative phosphoproteomics

7 January 2021

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Differential phosphoproteomics of fibroblast growth factor signaling: identification of Src family kinase-mediated phosphorylation events

7 January 2021

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Systems-wide analysis of a phosphatase knock-down by quantitative proteomics and phosphoproteomics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Higher-energy C-trap dissociation for peptide modification analysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

iTRAQ reagent-based quantitative proteomic analysis on a linear ion trap mass spectrometer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Peptide quantification using 8-plex isobaric tags and electron transfer dissociation tandem mass spectrometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Peptide and protein quantification using iTRAQ with electron transfer dissociation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Electron transfer dissociation of iTRAQ labeled peptide ions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Gaining efficiency by parallel quantification and identification of iTRAQ-labeled peptides using HCD and decision tree guided CID/ETD on an LTQ Orbitrap.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Combined pulsed-Q dissociation and electron transfer dissociation for identification and quantification of iTRAQ-labeled phosphopeptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Tandem Mass Tags: A Novel Quantification Strategy for Comparative Analysis of Complex Protein Mixtures by MS/MS

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Quantitative phosphoproteomic analysis of the STAT3/IL-6/HIF1alpha signaling network: an initial study in GSC11 glioblastoma stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Quantitation of peptides and proteins by matrix-assisted laser desorption/ionization mass spectrometry using (18)O-labeled internal standards

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Relative quantification of peptide phosphorylation in a complex mixture using 18O labeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Profiling signaling polarity in chemotactic cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Applying a targeted label-free approach using LC-MS AMT tags to evaluate changes in protein phosphorylation following phosphatase inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Quantitative time-resolved phosphoproteomic analysis of mast cell signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

A comparative phosphoproteomic analysis of a human tumor metastasis model using a label-free quantitative approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Comparison of label-free methods for quantifying human proteins by shotgun proteomics.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Correlation of Relative Abundance Ratios Derived from Peptide Ion Chromatograms and Spectrum Counting for Quantitative Proteomic Analysis Using Stable Isotope Labeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

A large-scale method to measure absolute protein phosphorylation stoichiometries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase a.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Identification and expression of delta-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Calcium-calcineurin signaling in the regulation of cardiac hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Differential regulation of p90 ribosomal S6 kinase and big mitogen-activated protein kinase 1 by ischemia/reperfusion and oxidative stress in perfused guinea pig hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Inhibition of p38 MAP kinase as a therapeutic strategy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

p38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Effects of inhibition of myocardial extracellular-responsive kinase and P38 mitogen-activated protein kinase on mechanical function of rat hearts after prolonged hypothermic ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Mechanisms of beta adrenoceptor desensitisation in the failing human heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Functional effects of endothelin and regulation of endothelin receptors in isolated human nonfailing and failing myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Selective downregulation of the angiotensin II AT1-receptor subtype in failing human ventricular myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

An essential role of the JAK-STAT pathway in ischemic preconditioning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

The myocardial JAK/STAT pathway: from protection to failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Activation of JAK/STAT pathway transduces cytoprotective signal in rat acute myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Targeting protein kinase B/Akt signaling with vanadium compounds for cardioprotection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Sevoflurane postconditioning protects chronically-infarcted rat hearts against ischemia-reperfusion injury by activation of pro-survival kinases and inhibition of mitochondrial permeability transition pore opening upon reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Formation of protein kinase C(epsilon)-Lck signaling modules confers cardioprotection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Functional proteomic analysis of protein kinase C epsilon signaling complexes in the normal heart and during cardioprotection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

PKCepsilon modulates NF-kappaB and AP-1 via mitogen-activated protein kinases in adult rabbit cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

The late phase of preconditioning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Isoform-selective activation of protein kinase C by nitric oxide in the heart of conscious rabbits: a signaling mechanism for both nitric oxide-induced and ischemia-induced preconditioning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Protein kinase C-epsilon is responsible for the protection of preconditioning in rabbit cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Ischemic Preconditioning Induces Selective Translocation of Protein Kinase C Isoforms and in the Heart of Conscious Rabbits Without Subcellular Redistribution of Total Protein Kinase C Activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

A selective epsilon-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Ischemic preconditioning protects by activating prosurvival kinases at reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Phosphodiesterases and cardiac cGMP: evolving roles and controversies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Regulation of cardiac contractile function by troponin I phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Cardiac troponin I phosphorylation increases the rate of cardiac muscle relaxation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Increased Ca2+-sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Analysis of cardiac myosin binding protein-C phosphorylation in human heart muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Myofibrillar remodeling in cardiac hypertrophy, heart failure and cardiomyopathies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Roles of cardiac ryanodine receptor in heart failure and sudden cardiac death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

The Ryanodine Receptor in Cardiac Physiology and Disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Regulation of cardiac ion channels by signaling complexes: role of modified leucine zipper motifs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Kinases as therapeutic targets for heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Inhibitors of protein kinase signaling pathways: emerging therapies for cardiovascular disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Protein kinase C epsilon signaling complexes include metabolism- and transcription/translation-related proteins: complimentary separation techniques with LC/MS/MS

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Proteomics study of oxidative stress and Src kinase inhibition in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Active kinase proteome screening reveals novel signal complexity in cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Chronic inhibition of Rho kinase blunts the process of left ventricular hypertrophy leading to cardiac contractile dysfunction in hypertension-induced heart failure.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

The Rho effector, PKN, regulates ANF gene transcription in cardiomyocytes through a serum response element

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

G-protein beta3 subunit and alpha-adducin polymorphisms and risk of subclinical and clinical stroke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Post-translational regulation of calsarcin-1 during pressure overload-induced cardiac hypertrophy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Pharmacologic perspectives of functional selectivity by the angiotensin II type 1 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Mitochondria: releasing power for life and unleashing the machineries of death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Mitochondria as integrators of signal transduction and energy production in cardiac physiology and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Kinase signaling cascades in the mitochondrion: a matter of life or death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Analysis of steady-state protein phosphorylation in mitochondria using a novel fluorescent phosphosensor dye.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Proteomics analysis of the cardiac myofilament subproteome reveals dynamic alterations in phosphatase subunit distribution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Regulation of murine cardiac 20S proteasomes: role of associating partners

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Decreased Serine207 phosphorylation of troponin T as a biomarker for left ventricular remodelling after myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Maximizing the sensitivity and reliability of peptide identification in large-scale proteomic experiments by harnessing multiple search engines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

Hydrophilic-interaction chromatography for the separation of peptides, nucleic acids and other polar compounds

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.06.001

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YJMCC.2012.06.001

1 reference

27 August 2017

1 reference