(Q38022529)

27 August 2017

title

The generation of "unnatural" products: synthetic biology meets synthetic chemistry (English)

1 reference

27 August 2017

1 reference

1

Rebecca J M Goss

0 references

Sreejith Shankar

object named as

Sreejith Shankar

series ordinal

2

0 references

author name string

Rebecca J M Goss

series ordinal

1

1 reference

27 August 2017

Antoine Abou Fayad

series ordinal

3

1 reference

27 August 2017

publication date

28 June 2012

1 reference

27 August 2017

published in

Natural Product Reports

1 reference

27 August 2017

volume

29

1 reference

27 August 2017

issue

8

1 reference

27 August 2017

page(s)

870-889

1 reference

Natural products as sources of new drugs over the 30 years from 1981 to 2010

27 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Natural products and combinatorial chemistry: back to the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Small molecule natural products in the discovery of therapeutic agents: the synthesis connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

On the potential of natural products in the discovery of pharma leads: a case for reassessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Genomic basis for natural product biosynthetic diversity in the actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

The impact of genomics on the exploitation of the myxobacterial secondary metabolome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Total synthesis approaches to natural product derivatives based on the combination of chemical synthesis and metabolic engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

The beta-lactam antibiotics: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Catalytic site-selective synthesis and evaluation of a series of erythromycin analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

An approach to the site-selective diversification of apoptolidin A with peptide-based catalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Site-selective bromination of vancomycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Stereochemical integrity of oxazolone ring-containing jadomycins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Mutasynthesis of rapamycin analogues through the manipulation of a gene governing starter unit biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

An expeditious route to fluorinated rapamycin analogues by utilising mutasynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Antimicrobial nucleoside antibiotics targeting cell wall assembly: recent advances in structure-function studies and nucleoside biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Purification and characterization of the bacterial MraY translocase catalyzing the first membrane step of peptidoglycan biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

New pacidamycin antibiotics through precursor-directed biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Precursor-directed biosynthesis of fluorinated iturin A in Bacillus spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Salinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Structure-activity relationship studies of salinosporamide A (NPI-0052), a novel marine derived proteasome inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Effects of halogens on the production of salinosporamides by the obligate marine actinomycete Salinispora tropica.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Mutasynthesis of fluorosalinosporamide, a potent and reversible inhibitor of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Biosynthesis of salinosporamides from alpha,beta-unsaturated fatty acids: implications for extending polyketide synthase diversity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Salinosporamide natural products: Potent 20 S proteasome inhibitors as promising cancer chemotherapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Auxotrophic-precursor directed biosynthesis of nonribosomal lipopeptides with modified tryptophan residues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Mutasynthesis-derived myxalamids and origin of the isobutyryl-CoA starter unit of myxalamid B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Mutasynthesis of geldanamycin by the disruption of a gene producing starter unit: generation of structural diversity at the benzoquinone ring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Potent non-benzoquinone ansamycin heat shock protein 90 inhibitors from genetic engineering of Streptomyces hygroscopicus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

New, highly active nonbenzoquinone geldanamycin derivatives by using mutasynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Generation of novel pikromycin antibiotic products through mutasynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Silencing of tryptamine biosynthesis for production of nonnatural alkaloids in plant culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Engineering broader specificity into an antibiotic-producing polyketide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Production of branched-chain alkylprodiginines in S. coelicolor by replacement of the 3-ketoacyl ACP synthase III initiation enzyme, RedP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Highly active ansamitocin derivatives: mutasynthesis using an AHBA-blocked mutant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Post-PKS tailoring steps in natural product-producing actinomycetes from the perspective of combinatorial biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Combinatorial biosynthesis of reduced polyketides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Combinatorial biosynthesis for drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Clorobiocin biosynthesis in Streptomyces: identification of the halogenase and generation of structural analogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Combinatorial biosynthesis of antitumor indolocarbazole compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Use of a halogenase of hormaomycin biosynthesis for formation of new clorobiocin analogues with 5-chloropyrrole moieties

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Integrating carbon-halogen bond formation into medicinal plant metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

DNA binding characteristics of mithramycin and chromomycin analogues obtained by combinatorial biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

The chromomycin CmmA acetyltransferase: a membrane-bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Protein-protein interactions in multienzyme megasynthetases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Total Synthesis of Rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Site-Selective Derivatization and Remodeling of Erythromycin A by Using Simple Peptide-Based Chiral Catalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2NP00001F

Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390

21 January 2018

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/ANIE.201007029

Identifiers

DOI

10.1039/C2NP00001F

1 reference

27 August 2017

1 reference