(Q38025162)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22780213%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia (English)

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7 February 2020

0 references

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1

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7 February 2020

author name string

Giovanni Pizzolo

series ordinal

2

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7 February 2020

publication date

1 June 2012

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Expert Review of Hematology

7 February 2020

published in

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7 February 2020

volume

5

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7 February 2020

issue

3

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7 February 2020

page(s)

341-348

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Genomic aberrations and survival in chronic lymphocytic leukemia

7 February 2020

cites work

1 reference

ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

21 January 2018

1 reference

The lymphatic tissue microenvironments in chronic lymphocytic leukemia: in vitro models and the significance of CD40-CD154 interactions

21 January 2018

1 reference

B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor

21 January 2018

1 reference

B-cell receptor signaling in chronic lymphocytic leukemia.

21 January 2018

1 reference

Antigen receptor tail clue.

21 January 2018

1 reference

B cell antigen receptor signaling 101.

21 January 2018

1 reference

Regulation of B-cell signal transduction by adaptor proteins

21 January 2018

1 reference

Initiation and processing of signals from the B cell antigen receptor

21 January 2018

1 reference

Calcium signalling and cell-fate choice in B cells

21 January 2018

1 reference

MAP kinases in the immune response

21 January 2018

1 reference

Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha

21 January 2018

1 reference

NFAT signaling: choreographing the social lives of cells

21 January 2018

1 reference

The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity

21 January 2018

1 reference

CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification

21 January 2018

1 reference

PI 3-kinase, Akt and cell survival

21 January 2018

1 reference

Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

1 reference

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

21 January 2018

1 reference

Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stage

21 January 2018

1 reference

Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling

21 January 2018

1 reference

Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells

21 January 2018

1 reference

Src family kinases: regulation of their activities, levels and identification of new pathways

21 January 2018

1 reference

Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells

21 January 2018

1 reference

The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia

21 January 2018

1 reference

The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target

21 January 2018

1 reference

Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy

21 January 2018

1 reference

Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling.

21 January 2018

1 reference

Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia

21 January 2018

1 reference

Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia

21 January 2018

1 reference

Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

21 January 2018

1 reference

Silencing of autoreactive B cells by anergy: a fresh perspective.

21 January 2018

1 reference

The role of the B-cell receptor in the pathogenesis of chronic lymphocytic leukaemia.

21 January 2018

1 reference

Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells.

21 January 2018

1 reference

Survival response to B-cell receptor ligation is restricted to progressive chronic lymphocytic leukemia cells irrespective of Zap70 expression.

21 January 2018

1 reference

BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells.

21 January 2018

1 reference

Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease.

21 January 2018

1 reference

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

21 January 2018

1 reference

Bcl-2 and apoptosis in chronic lymphocytic leukemia

21 January 2018

1 reference

A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells.

21 January 2018

1 reference

Rel a is an independent biomarker of clinical outcome in chronic lymphocytic leukemia.

21 January 2018

1 reference

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

21 January 2018

1 reference

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation.

21 January 2018

1 reference

B cell response to surface IgM cross-linking identifies different prognostic groups of B-chronic lymphocytic leukemia patients

21 January 2018

1 reference

Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial

21 January 2018

1 reference

Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells.

21 January 2018

1 reference

Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.

21 January 2018

1 reference

Microenvironmental influences in chronic lymphocytic leukaemia: the role of antigen stimulation

21 January 2018

1 reference

Chronic lymphocytic leukemia: revelations from the B-cell receptor.

21 January 2018

1 reference

Chronic lymphocytic leukemia

21 January 2018

1 reference

R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation

21 January 2018

1 reference

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia

21 January 2018

1 reference

The B cell antigen receptor controls integrin activity through Btk and PLCgamma2.

21 January 2018

1 reference

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

21 January 2018

1 reference

Inhibiting B-cell receptor signaling pathways in chronic lymphocytic leukemia

21 January 2018

1 reference

Safety, pharmacokinetics, and preliminary clinical activity of inotuzumab ozogamicin, a novel immunoconjugate for the treatment of B-cell non-Hodgkin's lymphoma: results of a phase I study

21 January 2018

1 reference

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.

21 January 2018

1 reference

The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo

21 January 2018

1 reference

The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia

21 January 2018

1 reference

B-Cell Receptor Translocation to Lipid Rafts and Associated Signaling Differ between Prognostically Important Subgroups of Chronic Lymphocytic Leukemia

21 January 2018

1 reference

Bruton's Tyrosine Kinase and Phospholipase Cγ2 Mediate Chemokine-Controlled B Cell Migration and Homing

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/EHM.12.21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22780213%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference