(Q38026746)

27 August 2017

Toward an integrative view of Optineurin functions (English)

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27 August 2017

David Kachaner

1

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27 August 2017

Pierre Génin

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2

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27 August 2017

Emmanuel Laplantine

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3

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27 August 2017

Robert Weil

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4

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27 August 2017

1 August 2012

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27 August 2017

11

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based on heuristic

inferred from page(s)

published in

Cell Cycle

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27 August 2017

11

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27 August 2017

15

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27 August 2017

2808-2818

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Interaction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains

27 August 2017

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Adult-onset primary open-angle glaucoma caused by mutations in optineurin

21 January 2018

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Cellular and molecular biology of optineurin

21 January 2018

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Molecular cloning, genomic structure, and protein characterization of mouse optineurin

21 January 2018

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Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway

21 January 2018

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NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB.

21 January 2018

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Ubiquitination in signaling to and activation of IKK.

21 January 2018

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NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

21 January 2018

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Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP

21 January 2018

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NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein

21 January 2018

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LUBAC, a novel ubiquitin ligase for linear ubiquitination, is crucial for inflammation and immune responses.

21 January 2018

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CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes

21 January 2018

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LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO

21 January 2018

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Optineurin is required for CYLD-dependent inhibition of TNFα-induced NF-κB activation

21 January 2018

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Optineurin and its mutants: molecules associated with some forms of glaucoma

21 January 2018

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Regulation of NF-κB signaling by the A20 deubiquitinase

21 January 2018

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Optineurin increases cell survival and translocates to the nucleus in a Rab8-dependent manner upon an apoptotic stimulus

21 January 2018

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FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

21 January 2018

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Huntingtin interacts with a family of WW domain proteins

21 January 2018

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The hunt for huntingtin function: interaction partners tell many different stories

21 January 2018

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Huntingtin-protein interactions and the pathogenesis of Huntington's disease

21 January 2018

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Hypothesis: Huntingtin may function in membrane association and vesicular trafficking

21 January 2018

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Huntingtin as an essential integrator of intracellular vesicular trafficking

21 January 2018

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Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus

21 January 2018

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Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes

21 January 2018

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Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

21 January 2018

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Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells

21 January 2018

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Myosin VI and optineurin are required for polarized EGFR delivery and directed migration

21 January 2018

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Loss of myosin VI reduces secretion and the size of the Golgi in fibroblasts from Snell's waltzer mice

21 January 2018

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Huntingtin facilitates dynein/dynactin-mediated vesicle transport.

21 January 2018

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Endocytic transport of integrins during cell migration and invasion.

21 January 2018

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Rab8-optineurin-myosin VI: analysis of interactions and functions in the secretory pathway

21 January 2018

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Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins

21 January 2018

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Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane.

21 January 2018

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RIG-I-like receptors: sensing and responding to RNA virus infection

21 January 2018

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Pathogen recognition by the innate immune system

21 January 2018

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Regulation of immunity and oncogenesis by the IRF transcription factor family

21 January 2018

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The receptor of the type I interferon family

21 January 2018

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Interferons at age 50: past, current and future impact on biomedicine

21 January 2018

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Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma

21 January 2018

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Convergence of the NF-kappaB and IRF pathways in the regulation of the innate antiviral response

21 January 2018

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Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection

21 January 2018

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Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon β.

21 January 2018

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Optineurin with amyotrophic lateral sclerosis-related mutations abrogates inhibition of interferon regulatory factor-3 activation

21 January 2018

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ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling

21 January 2018

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TBK1 protects vacuolar integrity during intracellular bacterial infection.

21 January 2018

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Homeostatic maintenance of pathogen-containing vacuoles requires TBK1-dependent regulation of aquaporin-1

21 January 2018

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Salmonellae interplay with host cells

21 January 2018

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Recognition of bacteria in the cytosol of Mammalian cells by the ubiquitin system

21 January 2018

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The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

21 January 2018

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

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The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway.

21 January 2018

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Processing of optineurin in neuronal cells

21 January 2018

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Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

21 January 2018

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Polo-like kinases: conservation and divergence in their functions and regulation

21 January 2018

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Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

21 January 2018

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Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry

21 January 2018

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Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1

21 January 2018

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Plk1-dependent phosphorylation of optineurin provides a negative feedback mechanism for mitotic progression

21 January 2018

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The genetics of primary open-angle glaucoma: a review

21 January 2018

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Molecular genetics in glaucoma

21 January 2018

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Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice

21 January 2018

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Defining the pathogenicity of optineurin in juvenile open-angle glaucoma.

21 January 2018

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Studies of optineurin, a glaucoma gene: Golgi fragmentation and cell death from overexpression of wild-type and mutant optineurin in two ocular cell types

21 January 2018

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Transgenic studies on the role of optineurin in the mouse eye.

21 January 2018

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Overexpressed mutant optineurin(E50K) induces retinal ganglion cells apoptosis via the mitochondrial pathway

21 January 2018

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Impairment of protein trafficking upon overexpression and mutation of optineurin

21 January 2018

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Mutations of optineurin in amyotrophic lateral sclerosis

21 January 2018

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Novel heterozygous nonsense mutation of the OPTN gene segregating in a Danish family with ALS.

21 January 2018

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Genetic determinants of Paget's disease of bone

21 January 2018

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Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone

21 January 2018

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FIP-2, an IkappaB-kinase-gamma-related protein, is associated with the Golgi apparatus and translocates to the marginal band during chicken erythroblast differentiation

21 January 2018

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Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant

21 January 2018

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Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation.

21 January 2018

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Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin

21 January 2018

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"Without Ub I am nothing": NEMO as a multifunctional player in ubiquitin-mediated control of NF-kappaB activation

21 January 2018

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Inhibition of autophagy in mitotic animal cells

21 January 2018

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Mitosis controls the Golgi and the Golgi controls mitosis.

21 January 2018

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Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS.

21 January 2018

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Angiopoietin-like 7 secretion is induced by glaucoma stimuli and its concentration is elevated in glaucomatous aqueous humor

21 January 2018

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The GH-IGF system in amyotrophic lateral sclerosis: correlations between pituitary GH secretion capacity, insulin-like growth factors and clinical features

21 January 2018

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Pathogenesis of Paget's disease of bone

21 January 2018

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Identification of a transcription factor IIIA-interacting protein

21 January 2018

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A tumor necrosis factor-alpha-mediated pathway promoting autosomal dominant polycystic kidney disease

21 January 2018

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Cell-free cotranslation and selection using in vitro virus for high-throughput analysis of protein-protein interactions and complexes

21 January 2018

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Primary open-angle glaucoma

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.4161/CC.20946

1 reference

27 August 2017

1 reference