(Q38040587)

27 August 2017

title

Metabolic regulation, mitochondria and the life-prolonging effect of rapamycin: a mini-review (English)

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27 August 2017

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4

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27 August 2017

Yong Pan

1

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27 August 2017

Yuya Nishida

series ordinal

2

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27 August 2017

Margaret Wang

series ordinal

3

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27 August 2017

language of work or name

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30 August 2012

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27 August 2017

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27 August 2017

volume

58

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issue

6

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27 August 2017

page(s)

524-530

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Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

27 August 2017

cites work

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Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

21 January 2018

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

21 January 2018

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Structure of the human mTOR complex I and its implications for rapamycin inhibition.

21 January 2018

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

21 January 2018

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RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

21 January 2018

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Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

21 January 2018

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A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa s6 kinase gene

21 January 2018

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4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila

21 January 2018

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Tor-mediated induction of autophagy via an Apg1 protein kinase complex

21 January 2018

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Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

21 January 2018

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Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity

21 January 2018

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Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice

21 January 2018

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Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster

21 January 2018

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Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

21 January 2018

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Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

21 January 2018

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Extension of chronological life span in yeast by decreased TOR pathway signaling

21 January 2018

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Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling

21 January 2018

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Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

21 January 2018

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Regulation of longevity and stress resistance by Sch9 in yeast

21 January 2018

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Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

21 January 2018

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Autophagy is required for extension of yeast chronological life span by rapamycin

21 January 2018

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Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration

21 January 2018

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Extended longevity in mice lacking the insulin receptor in adipose tissue

21 January 2018

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Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy

21 January 2018

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Aging and survival: the genetics of life span extension by dietary restriction.

21 January 2018

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Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening

21 January 2018

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Activation of a metabolic gene regulatory network downstream of mTOR complex 1

21 January 2018

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mTORC1 controls fasting-induced ketogenesis and its modulation by ageing.

21 January 2018

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A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

21 January 2018

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Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice.

21 January 2018

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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

21 January 2018

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Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation.

21 January 2018

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Autophagy regulates lipid metabolism

21 January 2018

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The mitochondrial theory of aging: insight from transgenic and knockout mouse models

21 January 2018

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Mitochondria, reactive oxygen species, and chronological aging: a message from yeast

21 January 2018

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mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

21 January 2018

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Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice

21 January 2018

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000342204

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27 August 2017

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