(Q38041728)

PubMed publication ID

22959030

27 August 2017

title

Resistance to chemotherapy: short-term drug tolerance and stem cell-like subpopulations (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6874398&resulttype=core&format=json

13 May 2020

author name string

Kevin J Basile

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6874398&resulttype=core&format=json

13 May 2020

Andrew E Aplin

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6874398&resulttype=core&format=json

13 May 2020

publication date

1 January 2012

1 reference

PubMed publication ID

22959030

27 August 2017

published in

Advances in Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6874398&resulttype=core&format=json

13 May 2020

volume

65

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6874398&resulttype=core&format=json

13 May 2020

page(s)

315-334

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6874398&resulttype=core&format=json

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

13 May 2020

cites work

1 reference

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mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy

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EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells

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Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line

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12 December 2020

Histone deacetylase inhibitors for epigenetic therapy of cancer

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12 December 2020

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

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12 December 2020

HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications

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12 December 2020

The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation

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12 December 2020

Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

1 reference

12 December 2020

FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells

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12 December 2020

Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis

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12 December 2020

PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells

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12 December 2020

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

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12 December 2020

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells

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12 December 2020

Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling

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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

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12 December 2020

OCT-4, an embryonic stem cell marker, is highly expressed in bladder cancer

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12 December 2020

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

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12 December 2020

Mutator phenotypes in human colorectal carcinoma cell lines

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12 December 2020

The therapeutic promise of the cancer stem cell concept

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12 December 2020

A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer

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12 December 2020

Mutations of the BRAF gene in human cancer

1 reference

12 December 2020

BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation

1 reference

12 December 2020

Adaptive upregulation of FOXD3 and resistance to PLX4032/4720-induced cell death in mutant B-RAF melanoma cells

1 reference

12 December 2020

DNA Demethylase Activity Maintains Intestinal Cells in an Undifferentiated State Following Loss of APC

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12 December 2020

Gatekeeper mutations mediate resistance to BRAF-targeted therapies.

1 reference

12 December 2020

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

1 reference

12 December 2020

Histone deacetylase inhibitors: overview and perspectives

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12 December 2020

Hyperactivation of MEK–ERK1/2 signaling and resistance to apoptosis induced by the oncogenic B-RAF inhibitor, PLX4720, in mutant N-RAS melanoma cells

1 reference

12 December 2020

A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

1 reference

12 December 2020

Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)

1 reference

12 December 2020

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

1 reference

12 December 2020

Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

1 reference

12 December 2020

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

1 reference

12 December 2020

Regulation of embryonic stem cell self-renewal and pluripotency by Foxd3

1 reference

12 December 2020

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

1 reference

12 December 2020

Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells

1 reference

12 December 2020

Stem cells, cancer, and cancer stem cells

1 reference

12 December 2020

Oncogenic RAS alters the global and gene-specific histone modification pattern during epithelial-mesenchymal transition in colorectal carcinoma cells

1 reference

12 December 2020

Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo

1 reference

12 December 2020

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

1 reference

12 December 2020

Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K

1 reference

12 December 2020

A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal

1 reference

12 December 2020

WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells

1 reference

12 December 2020

Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties

1 reference

12 December 2020

Microbial phenotypic heterogeneity and antibiotic tolerance.

1 reference

12 December 2020

Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.

1 reference

12 December 2020

Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

1 reference

12 December 2020

hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents

1 reference

12 December 2020

10.1016/B978-0-12-397927-8.00010-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6874398&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6874398&resulttype=core&format=json

13 May 2020

PubMed publication ID

22959030

1 reference