(Q38044415)

27 August 2017

title

Cell cycle regulation by the intrinsically disordered proteins p21 and p27. (English)

1 reference

27 August 2017

Mi-Kyung Yoon

1

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27 August 2017

Diana M Mitrea

series ordinal

2

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27 August 2017

Li Ou

series ordinal

3

1 reference

27 August 2017

Richard W Kriwacki

series ordinal

4

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27 August 2017

publication date

1 October 2012

1 reference

Biochemical Society Transactions

27 August 2017

published in

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27 August 2017

volume

40

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27 August 2017

issue

5

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27 August 2017

page(s)

981-988

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Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

27 August 2017

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Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21

21 January 2018

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The importance of intrinsic disorder for protein phosphorylation

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Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases

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Mechanical control of the directional stepping dynamics of the kinesin motor

21 January 2018

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Structural dynamics and multiregion interactions in dynein-dynactin recognition

21 January 2018

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A bimodal distribution of two distinct categories of intrinsically disordered structures with separate functions in FG nucleoporins

21 January 2018

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Critical scaffolding regions of the tumor suppressor Axin1 are natively unfolded

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Intrinsically unstructured proteins and their functions

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Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions?

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How viruses hijack cell regulation

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Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

21 January 2018

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Disordered p27Kip1 exhibits intrinsic structure resembling the Cdk2/cyclin A-bound conformation

21 January 2018

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Functional consequences of preorganized helical structure in the intrinsically disordered cell-cycle inhibitor p27(Kip1).

21 January 2018

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Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

21 January 2018

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Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners

21 January 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

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p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

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p21(Cip1) Promotes cyclin D1 nuclear accumulation via direct inhibition of nuclear export

21 January 2018

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New functional activities for the p21 family of CDK inhibitors

21 January 2018

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Switching cyclin D-Cdk4 kinase activity on and off.

21 January 2018

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p21-containing cyclin kinases exist in both active and inactive states

21 January 2018

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Mechanism of cell cycle entry mediated by the intrinsically disordered protein p27(Kip1).

21 January 2018

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Functional interaction of STAT3 transcription factor with the cell cycle inhibitor p21WAF1/CIP1/SDI1.

21 January 2018

1 reference

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p27Kip1 modulates cell migration through the regulation of RhoA activation.

21 January 2018

1 reference

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PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

21 January 2018

1 reference

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RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility

21 January 2018

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Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

21 January 2018

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Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity

21 January 2018

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The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

21 January 2018

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Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein

21 January 2018

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A proapoptotic function of p21 in differentiating granulocytes

21 January 2018

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p21 in cancer: intricate networks and multiple activities

21 January 2018

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CDK inhibitors: cell cycle regulators and beyond

21 January 2018

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Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120092

p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120092

Molecular basis for the specificity of p27 toward cyclin-dependent kinases that regulate cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120092

Speeding molecular recognition by using the folding funnel: the fly-casting mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120092

Crystal structure of human CDK4 in complex with a D-type cyclin

21 January 2018

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The structure of CDK4/cyclin D3 has implications for models of CDK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120092

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120092

Cdk2-dependent Inhibition of p21 stability via a C-terminal cyclin-binding motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120092

Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120092

Role of intrinsic flexibility in signal transduction mediated by the cell cycle regulator, p27 Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120092

Residual structure within the disordered C-terminal segment of p21(Waf1/Cip1/Sdi1) and its implications for molecular recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120092

p21Waf1/Cip1 as a therapeutic target in breast and other cancers

21 January 2018

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Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors

21 January 2018

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Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits

21 January 2018

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12 December 2020

Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription

1 reference

12 December 2020

p21(WAF1/Cip1): more than a break to the cell cycle?

1 reference

12 December 2020

Control of E2F activity by p21Waf1/Cip1

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12 December 2020

Identifiers

DOI

10.1042/BST20120092

1 reference

27 August 2017

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