(Q38058023)

27 August 2017

Nichotherapy for stem cells: there goes the neighborhood (English)

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27 August 2017

1

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27 August 2017

Ingrid G Winkler

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ORCID Public Data File 2021

author name string

John E J Rasko

series ordinal

3

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PubMed ID

23129341

27 August 2017

language of work or name

English

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publication date

5 November 2012

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27 August 2017

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27 August 2017

35

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27 August 2017

3

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27 August 2017

183-190

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The HSC niche concept has turned 31. Has our knowledge matured?

27 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

How I treat patients who mobilize hematopoietic stem cells poorly

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Cancer stem cells: impact, heterogeneity, and uncertainty

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Microenvironmental regulation of metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Niche contributions to oncogenesis: emerging concepts and implications for the hematopoietic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

The cancer stem cell niche--there goes the neighborhood?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

The leukemic stem cell niche: current concepts and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Development of a vascular niche platform for expansion of repopulating human cord blood stem and progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200111

Endothelial and perivascular cells maintain haematopoietic stem cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200111

Osteoblastic cells regulate the haematopoietic stem cell niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Hematopoiesis is severely altered in mice with an induced osteoblast deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Uncertainty in the niches that maintain haematopoietic stem cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201200111

Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Detection of functional haematopoietic stem cell niche using real-time imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Regulation of the HIF-1alpha level is essential for hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Mechanisms of hematopoietic stem cell mobilization: when innate immunity assails the cells that make blood and bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

The endosteal 'osteoblastic' niche and its role in hematopoietic stem cell homing and mobilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization d

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Improved granulocyte colony-stimulating factor mobilization of hemopoietic progenitors using cytokine combinations in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Phase III prospective randomized double-blind placebo-controlled trial of plerixafor plus granulocyte colony-stimulating factor compared with placebo plus granulocyte colony-stimulating factor for autologous stem-cell mobilization and transplantatio

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Dynamics of chronic myeloid leukemia response to long-term targeted therapy reveal treatment effects on leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Cytarabine dose for acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Therapeutic advances in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

A CXCR4 antagonist CTCE-9908 inhibits primary tumor growth and metastasis of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Involvement of chemokine receptors in breast cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Tumor-specific expression of alphavbeta3 integrin promotes spontaneous metastasis of breast cancer to bone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Interactions between cancer stem cells and their niche govern metastatic colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Niche competition and cancer metastasis to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Strategies for the discovery and development of therapies for metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Inflammation meets cancer, with NF-κB as the matchmaker

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

TGF-β-induced epithelial-mesenchymal transition of A549 lung adenocarcinoma cells is enhanced by pro-inflammatory cytokines derived from RAW 264.7 macrophage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Macrophage diversity enhances tumor progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Adenoviral-mediated endothelial precursor cell delivery of soluble CD115 suppresses human prostate cancer xenograft growth in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Tumor-infiltrating macrophages correlate with adverse prognosis and Epstein-Barr virus status in classical Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Tumor-associated macrophages and survival in classic Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

New Insights Into the Molecular Mechanisms of Action of Bisphosphonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Building a framework for embryonic microenvironments and cancer stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

Awakening dormant haematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201200111

21 January 2018

Identifiers

DOI

10.1002/BIES.201200111

1 reference

27 August 2017

1 reference

PubMed ID

23129341