(Q38062548)

28 August 2017

1 reference

title

Hormones and AID: balancing immunity and autoimmunity (English)

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28 August 2017

author

Kerstin-Maike Schmitz

series ordinal

4

object named as

Kerstin-Maike Schmitz

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28 August 2017

Elisabetta Incorvaia

1

1 reference

28 August 2017

Lara Sicouri

series ordinal

2

1 reference

28 August 2017

Svend K Petersen-Mahrt

series ordinal

3

1 reference

28 August 2017

publication date

10 January 2013

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28 August 2017

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28 August 2017

volume

46

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28 August 2017

issue

2

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28 August 2017

page(s)

128-137

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The MHC reactivity of the T cell repertoire prior to positive and negative selection.

28 August 2017

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The role of gender and organ specific autoimmunity

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Overexpression of the Ctla-4 isoform lacking exons 2 and 3 causes autoimmunity

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CTLA-4 can function as a negative regulator of T cell activation

21 January 2018

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Recent insights into the role and molecular mechanisms of the autoimmune regulator (AIRE) gene in autoimmunity.

21 January 2018

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The role of autoimmune regulator (Aire) in the development of the immune system

21 January 2018

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Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.

21 January 2018

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CD95's deadly mission in the immune system

21 January 2018

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The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity

21 January 2018

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Control of regulatory T cell development by the transcription factor Foxp3

21 January 2018

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Natural killer cells in human autoimmunity

21 January 2018

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Molecular mimicry as a mechanism of autoimmune disease

21 January 2018

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B cells as effectors and regulators of autoimmunity

21 January 2018

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B cell selection and susceptibility to autoimmunity

21 January 2018

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Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state

21 January 2018

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Multistep pathogenesis of autoimmune disease.

21 January 2018

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B-cell tolerance checkpoints in health and autoimmunity

21 January 2018

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https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Molecular mechanisms of autoimmunity

21 January 2018

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https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Definition of human autoimmunity--autoantibodies versus autoimmune disease

21 January 2018

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https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Regulation of immunity by self-reactive T cells

21 January 2018

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https://api.crossref.org/works/10.3109%2F08916934.2012.748752

The intrinsic hypermutability of antibody heavy and light chain genes decays exponentially

21 January 2018

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Does DNA repair occur during somatic hypermutation?

21 January 2018

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https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Immunoglobulin class-switch DNA recombination: induction, targeting and beyond

21 January 2018

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Molecular mechanisms of antibody somatic hypermutation.

21 January 2018

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https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Mechanism and regulation of class switch recombination

21 January 2018

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https://api.crossref.org/works/10.3109%2F08916934.2012.748752

A role for the RNA pol II-associated PAF complex in AID-induced immune diversification

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

DNA deamination in immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

DNA deamination mediates innate immunity to retroviral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Estrogen directly activates AID transcription and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Active nuclear import and cytoplasmic retention of activation-induced deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Expression of the AID protein in normal and neoplastic B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

AID is required for c-myc/IgH chromosome translocations in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Constitutive expression of AID leads to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

The cytoplasmic AID complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

The biochemistry of activation-induced deaminase and its physiological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Activation induced deaminase: how much and where?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

The balance between Pax5 and Id2 activities is the key to AID gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

miR-181b negatively regulates activation-induced cytidine deaminase in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Progesterone inhibits activation-induced deaminase by binding to the promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Sex differences in autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

A gender gap in autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Spotlight on the role of hormonal factors in the emergence of autoreactive B-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Suppression of B lymphopoiesis during normal pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Increased B lymphopoiesis in genetically sex steroid-deficient hypogonadal (hpg) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Oestrogen receptor specificity in oestradiol-mediated effects on B lymphopoiesis and immunoglobulin production in male mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Oestrogen is a potent disease accelerator in SLE-prone MRL lpr/lpr mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

17 beta-estradiol, but not 5 alpha-dihydrotestosterone, augments antibodies to double-stranded deoxyribonucleic acid in nonautoimmune C57BL/6J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Estrogen up-regulates Bcl-2 and blocks tolerance induction of naive B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Androgens in rheumatoid arthritis: when are they effectors?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Activation-induced deaminase contributes to the antibody-independent role of B cells in the development of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Activation-induced cytidine deaminase (AID) is required for B-cell tolerance in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Deficiency in activation-induced cytidine deaminase promotes systemic autoimmunity in lpr mice on a C57BL/6 background

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

V(D)J recombination: links to transposition and double-strand break repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Studies of the regulatory effects of the sex hormones on antibody formation and stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Mutational processes molding the genomes of 21 breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

The landscape of cancer genes and mutational processes in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

5-Methylcytosine DNA demethylation: more than losing a methyl group

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Estrogen induces a demethylation at the 5' end region of the chicken vitellogenin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Dynamics of estrogen receptor-mediated transcriptional activation of responsive genes in vivo: apprehending transcription in four dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Environmental exposure, estrogen and two X chromosomes are required for disease development in an epigenetic model of lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Agents with selective estrogen receptor (ER) modulator activity induce apoptosis in vitro and in vivo in ER-negative glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Genistein induces Gadd45 gene and G2/M cell cycle arrest in the DU145 human prostate cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Estrogen modulates NFκB signaling by enhancing IκBα levels and blocking p65 binding at the promoters of inflammatory genes via estrogen receptor-β.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

miRNAs and estrogen action

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Maturation of microRNA is hormonally regulated by a nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

MicroRNAs prevent the generation of autoreactive antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Role of microRNA-155 in autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Virus-induced autoimmunity: potential role of viruses in initiation, perpetuation, and progression of T-cell-mediated autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Infection of autoreactive B lymphocytes with EBV, causing chronic autoimmune diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Mechanisms for the induction of autoimmunity by infectious agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Epstein-Barr virus nuclear antigen 2 inhibits AID expression during EBV-driven B-cell growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Epstein-Barr virus infection of naïve B cells in vitro frequently selects clones with mutated immunoglobulin genotypes: implications for virus biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Physical interaction of Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) with human oestrogen-related receptor 1 (hERR1): hERR1 interacts with a conserved domain of EBNA-LP that is critical for EBV-induced B-cell immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Estrogen receptor alpha and estrogen receptor-related receptor alpha1 compete for binding and coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Regulation of AID expression in the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Increased expression of microRNA-155 in Epstein-Barr virus transformed lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

MicroRNA-155 is an Epstein-Barr virus-induced gene that modulates Epstein-Barr virus-regulated gene expression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Autoimmune lymphoproliferative syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Genetic Segregation of Spontaneous Erosive Arthritis and Generalized Autoimmune Disease in the BXD2 Recombinant Inbred Strain of Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

Influence of Sex on Immunoglobulin Levels

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2012.748752

10.3109/08916934.2012.748752

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

1 reference