(Q38063356)

28 August 2017

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title

Dual-specificity phosphatases 2: surprising positive effect at the molecular level and a potential biomarker of diseases (English)

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28 August 2017

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W Wei

1

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28 August 2017

Y Jiao

2

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28 August 2017

A Postlethwaite

3

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28 August 2017

J M Stuart

4

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28 August 2017

Y Wang

5

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28 August 2017

D Sun

6

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28 August 2017

W Gu

7

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28 August 2017

publication date

29 November 2012

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28 August 2017

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28 August 2017

volume

14

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28 August 2017

issue

1

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28 August 2017

page(s)

1-6

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The MAP Kinase Signaling Cascades: A System of Hundreds of Components Regulates a Diverse Array of Physiological Functions

28 August 2017

cites work

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Both nuclear-cytoplasmic shuttling of the dual specificity phosphatase MKP-3 and its ability to anchor MAP kinase in the cytoplasm are mediated by a conserved nuclear export signal

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MKP-7, a novel mitogen-activated protein kinase phosphatase, functions as a shuttle protein

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Suppression of dual-specificity phosphatase-2 by hypoxia increases chemoresistance and malignancy in human cancer cells

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Quantitative prediction of tumor response to neoadjuvant chemotherapy in breast cancer: novel marker genes and prediction model using the expression levels

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PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression

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The PAC-1 dual specificity phosphatase predicts poor outcome in serous ovarian carcinoma

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Mitogen-activated protein kinase phosphatase 2: a novel transcription target of p53 in apoptosis

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PAC1 is a direct transcription target of E2F-1 in apoptotic signaling

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A helminth immunomodulator exploits host signaling events to regulate cytokine production in macrophages

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PAC-1: a mitogen-induced nuclear protein tyrosine phosphatase

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Induction of the dual specificity phosphatase PAC1 in rat brain following seizure activity

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Antisense protein tyrosine phosphatase 1B reverses activation of p38 mitogen-activated protein kinase in liver of ob/ob mice

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Activation of the mitogen-activated protein kinase pathway induces transcription of the PAC-1 phosphatase gene

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MAP kinase phosphatases

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The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation

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Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1

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Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42.

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An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

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Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo

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The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

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The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition

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TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

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New insights into the catalytic activation of the MAPK phosphatase PAC-1 induced by its substrate MAPK ERK2 binding

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Solution Structure of the MAPK Phosphatase PAC-1 Catalytic Domain

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Epidermal growth factor receptor and protein kinase C signaling to ERK2: spatiotemporal regulation of ERK2 by dual specificity phosphatases

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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Proteomic identification of 14-3-3zeta as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand binding

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Regulation of monocyte subset proinflammatory responses within the lung microvasculature by the p38 MAPK/MK2 pathway

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21 January 2018

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Dual-specificity MAP kinase phosphatases (MKPs) and cancer

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Hypoxia-inhibited dual-specificity phosphatase-2 expression in endometriotic cells regulates cyclooxygenase-2 expression.

21 January 2018

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Analysis of potential biomarkers and modifier genes affecting the clinical course of CLN3 disease

21 January 2018

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Dual specificity phosphatases: a gene family for control of MAP kinase function.

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Regulation of ERK2 dephosphorylation in G1-stimulated rat T lymphoblasts

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.54

inferred from DOI database lookup

7 January 2021

based on heuristic

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.54

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/GENE.2012.54

1 reference

Dimensions Publication ID

28 August 2017

1047658079

0 references

1 reference