(Q38005668)

26 August 2017

title

Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update (English)

1 reference

26 August 2017

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John M Kyriakis

1

1 reference

26 August 2017

Joseph Avruch

series ordinal

2

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26 August 2017

publication date

1 April 2012

1 reference

26 August 2017

published in

Physiological Reviews

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26 August 2017

volume

92

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26 August 2017

issue

2

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26 August 2017

page(s)

689-737

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The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

26 August 2017

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Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

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Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades

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Targeting of immune signalling networks by bacterial pathogens

21 January 2018

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A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

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The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

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Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: potential role of p38 in the downregulation of GLUT4 expression.

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Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation

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Requirement of c-Jun NH(2)-terminal kinase for Ras-initiated tumor formation

21 January 2018

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Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.

21 January 2018

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JNK1 Is Required for Maintenance of Neuronal Microtubules and Controls Phosphorylation of Microtubule-Associated Proteins

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The kinases MEKK2 and MEKK3 regulate transforming growth factor-β-mediated helper T cell differentiation.

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway.

21 January 2018

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Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Isolation of the protein kinase TAO2 and identification of its mitogen-activated protein kinase/extracellular signal-regulated kinase kinase binding domain

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mammalian MAP kinase signalling cascades

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

TAB3, a new binding partner of the protein kinase TAK1

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

c-Jun NH(2)-terminal kinase inhibits targeting of the protein phosphatase calcineurin to NFATc1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Post-transcriptional gene regulation by MAP kinases via AU-rich elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Immune interventions of human diseases through toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Targeting protein kinases for the development of anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Irs1 serine 307 promotes insulin sensitivity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Emerging role of Toll-like receptors in atherosclerosis

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The JIP1 scaffold protein regulates axonal development in cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The Ste20 group kinases as regulators of MAP kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The role of JNK in the development of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Hsp25 and the p38 MAPK pathway are involved in differentiation of cardiomyocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MEK kinase 3 directly activates MKK6 and MKK7, specific activators of the p38 and c-Jun NH2-terminal kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The mammalian family of sterile 20p-like protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A cytoplasmic inhibitor of the JNK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

JNK is required for effector T-cell function but not for T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivative

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Cell cycle arrest and reversion of Ras-induced transformation by a conditionally activated form of mitogen-activated protein kinase kinase kinase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MEKK1 binds HECT E3 ligase Itch by its amino-terminal RING motif to regulate Th2 cytokine gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

14-3-3 proteins interact with specific MEK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

DNA damage-inducible transcripts in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MAPKAP kinases - MKs - two's company, three's a crowd

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Kinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mixed-lineage kinase control of JNK and p38 MAPK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

In vivo functions of mitogen-activated protein kinases: conclusions from knock-in and knock-out mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Transcription factor ATF2 regulation by the JNK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Apoptosis Signal-Regulating Kinase 1 Regulates Colitis and Colitis-Associated Tumorigenesis by the Innate Immune Responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MAP kinase pathways in yeast: for mating and more

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Differential activation of two JNK activators, MKK7 and SEK1, by MKN28-derived nonreceptor serine/threonine kinase/mixed lineage kinase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A central role for JNK in obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Transcriptional regulation by calcium, calcineurin, and NFAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Tumor necrosis factor alpha inhibits signaling from the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Metabolic stress signaling mediated by mixed-lineage kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Rho GTPases: biochemistry and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Convergence of MAP kinase pathways on the ternary complex factor Sap-1a

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Identification of a human NF-kappaB-activating protein, TAB3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Genetic disruption of p38alpha Tyr323 phosphorylation prevents T-cell receptor-mediated p38alpha activation and impairs interferon-gamma production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Defining MAPK interactomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Nrk: a murine X-linked NIK (Nck-interacting kinase)-related kinase gene expressed in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Multiple activation mechanisms of p38alpha mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

From JNK to pay dirt: jun kinases, their biochemistry, physiology and clinical importance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

POSH2 is a RING finger E3 ligase with Rac1 binding activity through a partial CRIB domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Signalling adaptors used by Toll-like receptors: an update.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MEKK3 is essential for lipopolysaccharide-induced interleukin-6 and granulocyte-macrophage colony-stimulating factor production in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Toll-like receptors: linking inflammation to metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Autophagy and the integrated stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The stress-activated protein kinase subfamily of c-Jun kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

HSP27 multimerization mediated by phosphorylation-sensitive intermolecular interactions at the amino terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Autophagy in immunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Three distinct signalling responses by murine fibroblasts to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Identification of c-Jun NH2-terminal protein kinase (JNK)-activating kinase 2 as an activator of JNK but not p38

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Partners in transcription: NFAT and AP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Smad transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Transcriptional regulation by the phosphorylation-dependent factor CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Integrating signals from RTKs to ERK/MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Intracellular pattern recognition receptors in the host response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Muscle-specific IRS-1 Ser->Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Ischemia and reperfusion enhance ATF-2 and c-Jun binding to cAMP response elements and to an AP-1 binding site from the c-jun promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

PRAK, a novel protein kinase regulated by the p38 MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MEX is a testis-specific E3 ubiquitin ligase that promotes death receptor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

ASK1 is essential for JNK/SAPK activation by TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Activated c-Jun N-terminal kinase is required for axon formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Roles of CHOP/GADD153 in endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphory

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Tumor progression locus 2 (TPL2) regulates obesity-associated inflammation and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Ubiquitination and TRAF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Phosphorylation of c-jun mediated by MAP kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

TLR8-mediated NF-κB and JNK Activation Are TAK1-independent and MEKK3-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

IL-10-induced TNF-alpha mRNA destabilization is mediated via IL-10 suppression of p38 MAP kinase activation and inhibition of HuR expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Differential regulation and properties of MAPKs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Regulation of the immune response by stress-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MAPKAP kinases MK2 and MK3 in inflammation: complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

RAF protein-serine/threonine kinases: Structure and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A stress signaling pathway in adipose tissue regulates hepatic insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Prevention of steatosis by hepatic JNK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The p38 MAP kinase pathway as a therapeutic target in inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The autoimmune suppressor Gadd45alpha inhibits the T cell alternative p38 activation pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Essential function for the kinase TAK1 in innate and adaptive immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Cloning and characterization of a human STE20-like protein kinase with unusual cofactor requirements

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The mechanism of action of cyclosporin A and FK506

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Stress-induced JNK activation is independent of Gadd45 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

AP-1 as a regulator of cell life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The mitogen-activated protein kinase kinase kinase kinase GCKR positively regulates canonical and noncanonical Wnt signaling in B lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Elimination of protein kinase MK5/PRAK activity by targeted homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Differential activation of ERK, p38, and JNK required for Th1 and Th2 deviation in myelin-reactive T cells induced by altered peptide ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene region

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The mRNA 5' cap-binding protein eIF4E and control of cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Interleukin-1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

p38-2, a novel mitogen-activated protein kinase with distinct properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

JNK is involved in signal integration during costimulation of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Inhibition of JNK activation through NF-kappaB target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A conserved docking motif in MAP kinases common to substrates, activators and regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Molecular recognitions in the MAP kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Regulation of transcription by MAP kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A novel human SPS1/STE20 homologue, KHS, activates Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Role of bone morphogenetic proteins in cardiac differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

c-Jun NH(2)-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MEKK3 regulates IFN-gamma production in T cells through the Rac1/2-dependent MAPK cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

gadd45 is not required for activation of c-Jun N-terminal kinase or p38 during acute stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Ablation of tumor progression locus 2 promotes a type 2 Th cell response in Ovalbumin-immunized mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The RAF proteins take centre stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Dissecting eIF4E action in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

IRS proteins and the common path to diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A mammalian scaffold complex that selectively mediates MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Requirement of the JIP1 scaffold protein for stress-induced JNK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Role of mitogen-activated protein kinase kinase 4 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Ubiquitylation of MEKK1 inhibits its phosphorylation of MKK1 and MKK4 and activation of the ERK1/2 and JNK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Direct activation of protein kinases by unanchored polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

JNK regulates FoxO-dependent autophagy in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mekk3 is essential for early embryonic cardiovascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Mammalian autophagy: core molecular machinery and signaling regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Activation of stress-activated protein kinases/c-Jun N-terminal protein kinases (SAPKs/JNKs) by a novel mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The JIP group of mitogen-activated protein kinase scaffold proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Regulation of the MEF2 family of transcription factors by p38

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Identification of Raf-1 S471 as a novel phosphorylation site critical for Raf-1 and B-Raf kinase activities and for MEK binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Defective T Cell Differentiation in the Absence of Jnk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Integration of MAP kinase signal transduction pathways at the serum response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00028.2011

10.1152/PHYSREV.00028.2011

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference