(Q38063413)

28 August 2017

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title

Making the brain glow: in vivo bioluminescence imaging to study neurodegeneration (English)

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28 August 2017

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2

Eva-Maria Mandelkow

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author name string

Katja Hochgräfe

series ordinal

1

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28 August 2017

29 November 2012

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28 August 2017

Molecular Neurobiology

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28 August 2017

47

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28 August 2017

3

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28 August 2017

868-882

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https://scigraph.springernature.com/pub.10.1007/s12035-012-8379-1

28 August 2017

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21 January 2018

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In vivo pathology: seeing with molecular specificity and cellular resolution in the living body

21 January 2018

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Inhibition of firefly luciferase by general anesthetics: effect on in vitro and in vivo bioluminescence imaging

21 January 2018

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Applications of bioluminescence imaging to antiviral research and therapy: multiple luciferase enzymes and quantitation

21 January 2018

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Guided by the light: visualizing biomolecular processes in living animals with bioluminescence

21 January 2018

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Validation of bioluminescent imaging techniques.

21 January 2018

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Evolution of beetle bioluminescence: the origin of beetle luciferin

21 January 2018

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Bioluminescence in the ocean: origins of biological, chemical, and ecological diversity

21 January 2018

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Visualizing gene expression in living mammals using a bioluminescent reporter.

21 January 2018

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Firefly bioluminescence: a mechanistic approach of luciferase catalyzed reactions.

21 January 2018

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Non-invasive in vivo characterization of breast tumors using photon migration spectroscopy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Live imaging of Toll-like receptor 2 response in cerebral ischaemia reveals a role of olfactory bulb microglia as modulators of inflammation.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Factors influencing quantification of in vivo bioluminescence imaging: application to assessment of pancreatic islet transplants.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Combined magnetic resonance and bioluminescence imaging of live mice.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

In vivo bioluminescence tomography with a blocking-off finite-difference SP3 method and MRI/CT coregistration

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Deep tissue optical and optoacoustic molecular imaging technologies for pre-clinical research and drug discovery.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Three-dimensional reconstruction of in vivo bioluminescent sources based on multispectral imaging

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Uptake kinetics and biodistribution of 14C-D-luciferin--a radiolabeled substrate for the firefly luciferase catalyzed bioluminescence reaction: impact on bioluminescence based reporter gene imaging

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Cell uptake and tissue distribution of radioiodine labelled D-luciferin: implications for luciferase based gene imaging.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

The molecular pathology of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Knock-out and transgenic mouse models of tauopathies.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Co-regulation of two gene activities by tetracycline via a bidirectional promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

A GFP-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Control of memory formation through regulated expression of a CaMKII transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Studying gene function in eukaryotes by conditional gene inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Bioluminescence imaging of reporter mice for studies of infection and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

A quantitative electron microscopic study of synaptogenesis in the dentate gyrus of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Neuronal Ca2+/calmodulin-dependent protein kinase II--discovery, progress in a quarter of a century, and perspective: implication for learning and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Degradation of tau protein by autophagy and proteasomal pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Firefly luciferase as a tool in molecular and cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Firefly luciferase is targeted to peroxisomes in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Kinetic analysis and modeling of firefly luciferase as a quantitative reporter gene in live mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Modulation of firefly luciferase stability and impact on studies of gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Analysis of proteome dynamics in the mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

GFAP in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Non-invasive imaging of GFAP expression after neuronal damage in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Dual transgenic reporter mice as a tool for monitoring expression of glial fibrillary acidic protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Live imaging of neuroinflammation reveals sex and estrogen effects on astrocyte response to ischemic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Real-time imaging of astrocyte response to quantum dots: in vivo screening model system for biocompatibility of nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

In vivo proliferation, migration and phenotypic changes of Schwann cells in the presence of myelinated fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Astrocytes in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

APP transgenic mice: their use and limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Purified and synthetic Alzheimer's amyloid beta (Aβ) prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Prion diseases: from protein to cell pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Measuring prions by bioluminescence imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Microglial activation in the injured and healthy brain: what are we really talking about? Practical and theoretical issues associated with the measurement of changes in microglial morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Lipopolysaccharide-QD micelles induce marked induction of TLR2 and lipid droplet accumulation in olfactory bulb microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

NF-kappaB functions in the nervous system: from development to disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Activation of NF-kappaB-dependent gene expression by silica in lungs of luciferase reporter mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Tracking early autoimmune disease by bioluminescent imaging of NF-kappaB activation reveals pathology in multiple organ systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

21 January 2018

Bioluminescence imaging

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Reoxygenation of hypoxic mice with 100% oxygen induces brain nuclear factor-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Antioxidant activity in the newborn brain: a luciferase mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Regulation of neural process growth, elaboration and structural plasticity by NF-κB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

A role for TGF-beta signaling in neurodegeneration: evidence from genetically engineered models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Bioluminescence analysis of Smad-dependent TGF-beta signaling in live mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Mechanisms and functional implications of adult neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Noninvasive and quantitative monitoring of adult neuronal stem cell migration in mouse brain using bioluminescence imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Clinical potential of intravenous neural stem cell delivery for treatment of neuroinflammatory disease in mice?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Molecular mechanisms, biological actions, and neuropharmacology of the growth-associated protein GAP-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Mitochondria in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Mitochondrial DNA toxicity in forebrain neurons causes apoptosis, neurodegeneration, and impaired behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

In vivo bioluminescent imaging (BLI): noninvasive visualization and interrogation of biological processes in living animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Reporter gene imaging of protein-protein interactions in living subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Current state of imaging protein-protein interactions in vivo with genetically encoded reporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Real-time imaging of beta-catenin dynamics in cells and living mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Proteasome inhibition blocks ligand-induced dynamic processing and internalization of epidermal growth factor receptor via altered receptor ubiquitination and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Real-time imaging of HIF-1alpha stabilization and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Noninvasive quantitative imaging of protein-protein interactions in living subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Molecular imaging of Akt kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Noninvasive imaging of apoptosis and its application in cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Noninvasive molecular imaging of apoptosis in vivo using a modified firefly luciferase substrate, Z-DEVD-aminoluciferin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Biosensing and imaging based on bioluminescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Bioluminescence resonance energy transfer (BRET) imaging of protein-protein interactions within deep tissues of living subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Red-shifted Renilla reniformis luciferase variants for imaging in living subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

BRET-based method for detection of specific RNA species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Rational design of novel red-shifted BRET pairs: Platforms for real-time single-chain protease biosensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Bioluminescence imaging of myeloperoxidase activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

In vivo imaging of hydrogen peroxide with chemiluminescent nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Dynamic optical imaging of metabolic and NADPH oxidase-derived superoxide in live mouse brain using fluorescence lifetime unmixing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

A significant improvement of the efficacy of radical oxidant probes by the kinetic isotope effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Molecular optical imaging with radioactive probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Optical imaging of Cerenkov light generation from positron-emitting radiotracers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Validating Bioluminescence Imaging as a High-Throughput, Quantitative Modality for Assessing Tumor Burden

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8379-1

Pharmacology and toxicology of doxycycline

21 January 2018

1 reference

12 December 2020

Bioluminescence imaging of the brain response to acute inflammation in living C/EBP reporter mice

1 reference

12 December 2020

Role of nuclear factor kappaB in the central nervous system.

1 reference

12 December 2020

Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses

1 reference

12 December 2020

Multiorgan nuclear factor kappa B activation in a transgenic mouse model of systemic inflammation

1 reference

12 December 2020

Transgenic animal models of tauopathies

1 reference

12 December 2020

In vivo optical imaging of neurogenesis: watching new neurons in the intact brain

1 reference

12 December 2020

The beta-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy

1 reference

12 December 2020

In vivo imaging of NF-kappa B activity

1 reference

12 December 2020

Model system for live imaging of neuronal responses to injury and repair.

1 reference

12 December 2020

Live imaging of amyotrophic lateral sclerosis pathogenesis: disease onset is characterized by marked induction of GFAP in Schwann cells

1 reference

12 December 2020

In situ hybridization histochemistry of Ca2+/calmodulin-dependent protein kinase in developing rat brain.

1 reference

12 December 2020

10.1007/S12035-012-8379-1

Identifiers

DOI

1 reference

PubMed ID

23192390

Dimensions Publication ID

28 August 2017

0 references

1 reference

PubMed ID

23192390