(Q38064157)

28 August 2017

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title

Interactions of the GnRH receptor with heterotrimeric G proteins (English)

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28 August 2017

2

Ilpo Huhtaniemi

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28 August 2017

Zvi Naor

1

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28 August 2017

27 November 2012

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Frontiers in Neuroendocrinology

28 August 2017

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28 August 2017

34

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28 August 2017

2

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28 August 2017

88-94

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The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs

28 August 2017

1 reference

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Pulsatile and sustained gonadotropin-releasing hormone (GnRH) receptor signaling: does the ERK signaling pathway decode GnRH pulse frequency?

7 January 2021

1 reference

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Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation

7 January 2021

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GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Extracellular signal-regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone follicle-stimulating hormone beta-subunit promoter

7 January 2021

1 reference

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Regulation of Luteinizing Hormone-β and Follicle-Stimulating Hormone (FSH)-β Gene Transcription by Androgens: Testosterone Directly Stimulates FSH-β Transcription Independent from Its Role on Follistatin Gene Expression

7 January 2021

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Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP

7 January 2021

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G proteins and autocrine signaling differentially regulate gonadotropin subunit expression in pituitary gonadotrope

7 January 2021

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The frequency of gonadotropin-releasing-hormone stimulation differentially regulates gonadotropin subunit messenger ribonucleic acid expression

7 January 2021

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Cytoskeletal reorganization dependence of signaling by the gonadotropin-releasing hormone receptor

7 January 2021

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Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

7 January 2021

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A family with hypogonadotropic hypogonadism and mutations in the gonadotropin-releasing hormone receptor

7 January 2021

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A preformed signaling complex mediates GnRH-activated ERK phosphorylation of paxillin and FAK at focal adhesions in L beta T2 gonadotrope cells.

7 January 2021

1 reference

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Differential role of PKC isoforms in GnRH and phorbol 12-myristate 13-acetate activation of extracellular signal-regulated kinase and Jun N-terminal kinase

7 January 2021

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Effects of LHRH-analogues on mitogenic signal transduction in cancer cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Role of the transmembrane domain 4/extracellular loop 2 junction of the human gonadotropin-releasing hormone receptor in ligand binding and receptor conformational selection.

7 January 2021

1 reference

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Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

7 January 2021

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Gonadotropin-releasing hormone induces miR-132 and miR-212 to regulate cellular morphology and migration in immortalized LbetaT2 pituitary gonadotrope cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Gonadotropin-releasing hormone receptor initiates multiple signaling pathways by exclusively coupling to G(q/11) proteins.

7 January 2021

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Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors

7 January 2021

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Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein alpha(I)-mediated activation of phosphotyrosine phosphatase

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

The many faces of G protein signaling

7 January 2021

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Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation

7 January 2021

1 reference

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Recognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs

7 January 2021

1 reference

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Escaping the flatlands: new approaches for studying the dynamic assembly and activation of GPCR signaling complexes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Gi protein activation of gonadotropin-releasing hormone-mediated protein dephosphorylation in human endometrial carcinoma

7 January 2021

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Agonist-receptor efficacy. II. Agonist trafficking of receptor signals

7 January 2021

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Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery

7 January 2021

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Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Gonadotropin-releasing hormone in apoptosis of prostate cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

An agonist-induced switch in G protein coupling of the gonadotropin-releasing hormone receptor regulates pulsatile neuropeptide secretion.

7 January 2021

1 reference

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Gonadotropin-releasing hormone couples to 3',5'-cyclic adenosine-5'-monophosphate pathway through novel protein kinase Cdelta and -epsilon in LbetaT2 gonadotrope cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Negative feedback governs gonadotrope frequency-decoding of gonadotropin releasing hormone pulse-frequency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Androgen-dependent prostatic tumors: biosynthesis and possible actions of LHRH.

7 January 2021

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The biology of gonadotropin hormone-releasing hormone: role in the control of tumor growth and progression in humans

7 January 2021

1 reference

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Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Signalosomes in the brain: relevance in the development of certain neuropathologies such as Alzheimer's disease

7 January 2021

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Gonadotropin-releasing hormone (GnRH) antagonists promote proapoptotic signaling in peripheral reproductive tumor cells by activating a Galphai-coupling state of the type I GnRH receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Outside-In and Inside-Out Signaling: The New Concept that Selectivity of Ligand Binding at the Gonadotropin-Releasing Hormone Receptor Is Modulated by the Intracellular Environment

7 January 2021

1 reference

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Gonadotropin-releasing hormone receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Diversity of actions of GnRHs mediated by ligand-induced selective signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Signaling by G-protein-coupled receptor (GPCR): studies on the GnRH receptor

7 January 2021

1 reference

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Reciprocal cross talk between gonadotropin-releasing hormone (GnRH) and prostaglandin receptors regulates GnRH receptor expression and differential gonadotropin secretion

7 January 2021

1 reference

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Neuroendocrine plasticity in the anterior pituitary: gonadotropin-releasing hormone-mediated movement in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Heterotrimeric G proteins: organizers of transmembrane signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

7 January 2021

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A CD40 Signalosome anchored in lipid rafts leads to constitutive activation of NF-kappaB and autonomous cell growth in B cell lymphomas

7 January 2021

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Gbeta3 forms distinct dimers with specific Ggamma subunits and preferentially activates the beta3 isoform of phospholipase C.

7 January 2021

1 reference

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

7 January 2021

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Prostaglandins and inflammation

7 January 2021

1 reference

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The structure and function of G-protein-coupled receptors

7 January 2021

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Mixed analog/digital gonadotrope biosynthetic response to gonadotropin-releasing hormone.

7 January 2021

1 reference

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Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor

7 January 2021

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IUPHAR-DB: new receptors and tools for easy searching and visualization of pharmacological data

7 January 2021

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Gonadotropin-releasing hormone receptor couples to multiple G proteins in rat gonadotrophs and in GGH3 cells: evidence from palmitoylation and overexpression of G proteins

7 January 2021

1 reference

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Steroid and pulsatile gonadotropin-releasing hormone (GnRH) regulation of luteinizing hormone and GnRH receptor in a novel gonadotrope cell line

7 January 2021

1 reference

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Macrophage inflammatory protein 2 inhibits beta-amyloid peptide (1-42)-mediated hippocampal neuronal apoptosis through activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways

7 January 2021

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The T-cell receptor signalosome: a dynamic structure with expanding complexity

7 January 2021

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Antiproliferative effects of GnRH agonists: prospects and problems for cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

A crucial role for Galphaq/11, but not Galphai/o or Galphas, in gonadotropin-releasing hormone receptor-mediated cell growth inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Cell Lines of the Pituitary Gonadotrope Lineage Derived by Targeted Oncogenesis in Transgenic Mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

The ERK Cascade: Distinct Functions within Various Subcellular Organelles

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YFRNE.2012.11.001

Gonadotropin-releasing hormone type II induces apoptosis of human endometrial cancer cells by activating GADD45alpha.

7 January 2021

1 reference

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Optimized amplification and single-cell analysis identify GnRH-mediated activation of Rap1b in primary rat gonadotropes

7 January 2021

1 reference

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10.1016/J.YFRNE.2012.11.001

7 January 2021

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23200814