(Q38065057)

28 August 2017

1 reference

title

Dual roles of PKM2 in cancer metabolism (English)

1 reference

28 August 2017

Songfang Wu

1

1 reference

PubMed ID

23212076

28 August 2017

Huangying Le

series ordinal

2

1 reference

28 August 2017

4 December 2012

1 reference

Acta Biochimica et Biophysica Sinica

28 August 2017

1 reference

28 August 2017

45

1 reference

28 August 2017

1

1 reference

28 August 2017

27-35

1 reference

Hallmarks of Cancer: The Next Generation

28 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

On the Origin of Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Identification of a transformation-specific antigen induced by an avian sarcoma virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Role of the stimulatory proteins Sp1 and Sp3 in the regulation of transcription of the rat pyruvate kinase M gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Human pyruvate kinase M2: a multifunctional protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Effects of the human papilloma virus HPV-16 E7 oncoprotein on glycolysis and glutaminolysis: role of pyruvate kinase type M2 and the glycolytic-enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Cell signaling by receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Pyruvate kinase M2 is a phosphotyrosine-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Association of the src gene product of Rous sarcoma virus with cytoskeletal structures of chicken embryo fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Modulation of type M2 pyruvate kinase activity by the human papillomavirus type 16 E7 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Pyrimidine pathways in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Regulation of cell proliferation by interleukin-3-induced nuclear translocation of pyruvate kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Interaction between HERC1 and M2-type pyruvate kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

The M2-type isoenzyme of pyruvate kinase phosphorylates prothymosin α in proliferating lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Balancing biosynthesis and bioenergetics: metabolic programs in oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

PKM2 tyrosine phosphorylation and glutamine metabolism signal a different view of the Warburg effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Efficacy of RNAi targeting of pyruvate kinase M2 combined with cisplatin in a lung cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Prolactin inhibits activity of pyruvate kinase M2 to stimulate cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

Identification of small molecule inhibitors of pyruvate kinase M2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMS106

21 January 2018

Identifiers

DOI

10.1093/ABBS/GMS106

1 reference

28 August 2017

1 reference

PubMed ID

23212076