(Q38065324)

28 August 2017

1 reference

title

Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force (English)

1 reference

28 August 2017

0 references

1 reference

F Polet

1

1 reference

PubMed ID

23216817

28 August 2017

O Feron

series ordinal

2

1 reference

PubMed ID

23216817

28 August 2017

language of work or name

English

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publication date

1 February 2013

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Journal of Internal Medicine

28 August 2017

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28 August 2017

273

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28 August 2017

2

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28 August 2017

156-165

1 reference

Structural response of microcirculatory networks to changes in demand: information transfer by shear stress.

28 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Regulation of oxygen distribution in tissues by endothelial nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Nitric oxide delivery to cancer: why and how?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Targeting cancer metabolism: a therapeutic window opens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Regulation of angiogenesis by oxygen and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Imaging cycling tumor hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Physiological noise in murine solid tumours using T2*-weighted gradient-echo imaging: a marker of tumour acute hypoxia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Quantifying transient hypoxia in human tumor xenografts by flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Direct demonstration of instabilities in oxygen concentrations within the extravascular compartment of an experimental tumor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Fluctuations in tumor blood perfusion assessed by dynamic contrast-enhanced MRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Fluctuating and diffusion-limited hypoxia in hypoxia-induced metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Identification of cyclooxygenase-2 as a major actor of the transcriptomic adaptation of endothelial and tumor cells to cyclic hypoxia: effect on angiogenesis and metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Preconditioning of the tumor vasculature and tumor cells by intermittent hypoxia: implications for anticancer therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Reversal of temporal and spatial heterogeneities in tumor perfusion identifies the tumor vascular tone as a tunable variable to improve drug delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

The therapeutic potential of ischemic conditioning: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Cooperation and competition in the evolution of ATP-producing pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Glutamine addiction: a new therapeutic target in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Premature senescence of human endothelial cells induced by inhibition of glutaminase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Expression of angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 is highly responsive to ambient glutamine availability: role of nuclear factor-kappaB and activating protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Lactate: a metabolic key player in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Inhibition of HIF prolyl hydroxylase-2 blocks tumor growth in mice through the antiproliferative activity of TGFβ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

PHD2 in tumour angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

The prolyl-hydroxylase EGLN3 and not EGLN1 is inactivated by methylation in plasma cell neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Antiangiogenic therapy: impact on invasion, disease progression, and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Basic and therapeutic aspects of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Challenges in pharmacology of anti-cancer drugs - the search for addictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

Lactate shuttles at a glance: from physiological paradigms to anti-cancer treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12016

21 January 2018

Identifiers

DOI

10.1111/JOIM.12016

1 reference

28 August 2017

1 reference

PubMed ID

23216817