(Q38066563)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231425%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

review article

1 reference

title

Targeting apicoplasts in malaria parasites (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231425%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231425%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Geoffrey Ian McFadden

series ordinal

2

object named as

Geoffrey I McFadden

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231425%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

language of work or name

English

0 references

publication date

11 December 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231425%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

20 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231425%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231425%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231425%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

page(s)

167-177

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231425%20AND%20SRC:MED&resulttype=core&format=json

Drug resistance and genetic mapping in Plasmodium falciparum.

20 February 2020

cites work

1 reference

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Complete gene map of the plastid-like DNA of the malaria parasite Plasmodium falciparum

21 January 2018

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A plastid of probable green algal origin in Apicomplexan parasites.

21 January 2018

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Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Plastids in parasites of humans

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast

21 January 2018

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Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum

21 January 2018

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Eukaryotic systematics: a user's guide for cell biologists and parasitologists

21 January 2018

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The Revised Classification of Eukaryotes

21 January 2018

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Evolution of the apicoplast and its hosts: from heterotrophy to autotrophy and back again

21 January 2018

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A photosynthetic alveolate closely related to apicomplexan parasites.

21 January 2018

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Morphology, ultrastructure and life cycle of Vitrella brassicaformis n. sp., n. gen., a novel chromerid from the Great Barrier Reef

21 January 2018

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A common red algal origin of the apicomplexan, dinoflagellate, and heterokont plastids

21 January 2018

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Dissecting apicoplast targeting in the malaria parasite Plasmodium falciparum

21 January 2018

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Characterization of two putative protein translocation components in the apicoplast of Plasmodium falciparum

21 January 2018

1 reference

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Enzymes for heme biosynthesis are found in both the mitochondrion and plastid of the malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

An unusual ERAD-like complex is targeted to the apicoplast of Plasmodium falciparum

21 January 2018

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Global analysis of plastid diversity reveals apicomplexan-related lineages in coral reefs.

21 January 2018

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Membrane transporters in the relict plastid of malaria parasites

21 January 2018

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Oxygen- and time-dependent effects of antibiotics and selected mitochondrial inhibitors on Plasmodium falciparum in culture

21 January 2018

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Increased antimalarial activity of azithromycin during prolonged exposure of Plasmodium falciparum in vitro

21 January 2018

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The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

A plastid segregation defect in the protozoan parasite Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

A plastid organelle as a drug target in apicomplexan parasites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

The effects of anti-bacterials on the malaria parasite Plasmodium falciparum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Chemistry and biology of macrolide antiparasitic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Thiostrepton and derivatives exhibit antimalarial and gametocytocidal activity by dually targeting parasite proteasome and apicoplast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Identifying apicoplast-targeting antimalarials using high-throughput compatible approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Natural immunization against malaria: causal prophylaxis with antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

21 January 2018

Fosmidomycin for malaria

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Fosmidomycin, a novel chemotherapeutic agent for malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

The plastid-like organelle of apicomplexan parasites as drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Synthesis and biological evaluation of cyclopropyl analogues of fosmidomycin as potent Plasmodium falciparum growth inhibitors.

21 January 2018

1 reference

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Synthesis of beta- and gamma-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Synthesis of alpha-substituted fosmidomycin analogues as highly potent Plasmodium falciparum growth inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling

21 January 2018

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Nonphosphate inhibitors of IspE protein, a kinase in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy.

21 January 2018

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The MEP pathway: a new target for the development of herbicides, antibiotics and antimalarial drugs.

21 January 2018

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Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Antimalarial exposure delays Plasmodium falciparum intra-erythrocytic cycle and drives drug transporter genes expression

21 January 2018

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Artemisinin‐induced dormancy in plasmodium falciparum: duration, recovery rates, and implications in treatment failure

21 January 2018

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Plasmodium pyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Unique properties of Plasmodium falciparum porphobilinogen deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Mitochondrial localization of functional ferrochelatase from Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Involvement of delta-aminolaevulinate synthase encoded by the parasite gene in de novo haem synthesis by Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Localization of ferrochelatase in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Processing of an apicoplast leader sequence in Plasmodium falciparum and the identification of a putative leader cleavage enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Protoporphyrinogen IX oxidase from Plasmodium falciparum is anaerobic and is localized to the mitochondrion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Apicoplast and mitochondrion in gametocytogenesis of Plasmodium falciparum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Gene transfer from organelles to the nucleus: frequent and in big chunks

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Genetic evidence that an endosymbiont-derived endoplasmic reticulum-associated protein degradation (ERAD) system functions in import of apicoplast proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Malaria, Plasmodium falciparum and its apicoplast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Toxoplasma gondii Tic20 is essential for apicoplast protein import

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

15-deoxyspergualin primarily targets the trafficking of apicoplast proteins in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

15-Deoxyspergualin hinders physical interaction between basic residues of transit peptide in PfENR and Hsp70-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

15-deoxyspergualin inhibits eukaryotic protein synthesis through eIF2alpha phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Reconstitution of an apicoplast-localised electron transfer pathway involved in the isoprenoid biosynthesis of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Eukaryotic genomes contain a [2Fez.sbnd;2S] ferredoxin isoform with a conserved C-terminal sequence motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Metabolic maps and functions of the Plasmodium mitochondrion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Apicomplexan parasites possess distinct nuclear-encoded, but apicoplast-localized, plant-type ferredoxin-NADP+ reductase and ferredoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Ferredoxin-NADP+ reductase from Plasmodium falciparum undergoes NADP+-dependent dimerization and inactivation: functional and crystallographic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

The plant-type ferredoxin-NADP+ reductase/ferredoxin redox system as a possible drug target against apicomplexan human parasites.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.739158

The ferredoxin-NADP+ reductase/ferredoxin electron transfer system of Plasmodium falciparum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Plasmodium falciparum ferredoxin-NADP+ reductase His286 plays a dual role in NADP(H) binding and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

The malaria parasite Plasmodium falciparum has only one pyruvate dehydrogenase complex, which is located in the apicoplast

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Nucleoside/nucleobase transporters: drug targets of the future?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Ion channel drug discovery: challenges and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Apicoplast targeting of a Toxoplasma gondii transmembrane protein requires a cytosolic tyrosine-based motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

The carbon and energy sources of the non-photosynthetic plastid in the malaria parasite

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Transport of isoprenoid intermediates across chloroplast envelope membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Artemisinin directly targets malarial mitochondria through its specific mitochondrial activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

The Plasmodium falciparum Ca 2+ -ATPase PfATP6: insensitive to artemisinin, but a potential drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Artemisinins target the SERCA of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Reaction of artemisinin with haemoglobin: implications for antimalarial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158

Plastid in human parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.739158