(Q38074594)

28 August 2017

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title

Serpins, immunity and autoimmunity: old molecules, new functions (English)

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28 August 2017

Andrea Doria

8

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Leonardo Punzi

object named as

Leonardo Punzi

6

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Yehuda Shoenfeld

7

object named as

Yehuda Shoenfeld

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28 August 2017

Mariele Gatto

1

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28 August 2017

Luca Iaccarino

2

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28 August 2017

Anna Ghirardello

3

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28 August 2017

Nicola Bassi

4

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28 August 2017

Patrizia Pontisso

5

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28 August 2017

publication date

1 October 2013

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Clinical Reviews in Allergy & Immunology

28 August 2017

published in

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28 August 2017

volume

45

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28 August 2017

issue

2

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28 August 2017

page(s)

267-280

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https://scigraph.springernature.com/pub.10.1007/s12016-013-8353-3

28 August 2017

exact match

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cites work

Serpin structure, mechanism, and function

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Serpin structure, function and dysfunction

21 January 2018

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Evolutionary families of peptidase inhibitors

21 January 2018

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The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

21 January 2018

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An overview of the serpin superfamily

21 January 2018

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The role of serpins in vertebrate immunity

21 January 2018

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Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.

21 January 2018

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Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Serpins in T cell immunity

21 January 2018

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Control of granzymes by serpins.

21 January 2018

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Serpins: finely balanced conformational traps

21 January 2018

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Recent progress in understanding the diversity of the human ov-serpin/clade B serpin family.

21 January 2018

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Shape-shifting serpins--advantages of a mobile mechanism

21 January 2018

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Role of the catalytic serine in the interactions of serine proteinases with protein inhibitors of the serpin family. Contribution of a covalent interaction to the binding energy of serpin-proteinase complexes.

21 January 2018

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A surprising new protein superfamily containing ovalbumin, antithrombin-III, and alpha 1-proteinase inhibitor

21 January 2018

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Serpins: structure, function and molecular evolution.

21 January 2018

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The ovalbumin serpins revisited: perspective from the chicken genome of clade B serpin evolution in vertebrates

21 January 2018

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Conformational properties of serine proteinase inhibitors (serpins) confer multiple pathophysiological roles

21 January 2018

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The undecided serpin. The ins and outs of plasminogen activator inhibitor type 2.

21 January 2018

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Mesangial cell-predominant functional gene, megsin

21 January 2018

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New insight into serpin polymerization and aggregation

21 January 2018

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Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization

21 January 2018

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Molecular gymnastics: serpin structure, folding and misfolding

21 January 2018

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Polymers and inflammation: disease mechanisms of the serpinopathies

21 January 2018

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Conformational pathology of the serpins: themes, variations, and therapeutic strategies

21 January 2018

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The molecular aetiology of the serpinopathies

21 January 2018

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Alpha1-antitrypsin polymerization and the serpinopathies: pathobiology and prospects for therapy

21 January 2018

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Serpinopathy and endoplasmic reticulum stress

21 January 2018

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Unravelling the twists and turns of the serpinopathies.

21 January 2018

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Novel serpinopathy in rat kidney and pancreas induced by overexpression of megsin

21 January 2018

1 reference

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Analysis of vertebrate genomes suggests a new model for clade B serpin evolution.

21 January 2018

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The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency

21 January 2018

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Ovalbumin: a secreted protein without a transient hydrophobic leader sequence

21 January 2018

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Maspin is an intracellular serpin that partitions into secretory vesicles and is present at the cell surface

21 January 2018

1 reference

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Secretion of plasminogen activator inhibitor 2 by human peripheral blood monocytes occurs via an endoplasmic reticulum-golgi-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Evidence that serpin architecture intrinsically supports papain-like cysteine protease inhibition: engineering alpha(1)-antitrypsin to inhibit cathepsin proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Regulation of pro-apoptotic leucocyte granule serine proteinases by intracellular serpins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Stage specific gene expression of serpins and their cognate proteases during myeloid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Serpins prevent granzyme-induced death in a species-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

SERPINB3 expression on B-cell surface in autoimmune diseases and hepatitis C virus-related chronic liver infection.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

SERPINB3, apoptosis and autoimmunity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Elevated expression of squamous cell carcinoma antigen (SCCA) is associated with human breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Anti-apoptotic effects of SERPIN B3 and B4 via STAT6 activation in macrophages after infection with Toxoplasma gondii

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Hepatitis B virus binds to peripheral blood mononuclear cells via the pre S1 protein

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Biological and clinical implications of HBV infection in peripheral blood mononuclear cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Humoral autoimmune responses to the squamous cell carcinoma antigen protein family in psoriasis.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Acquired C1-inhibitor deficiency in a patient with systemic lupus erythematosus: a case report and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Enhanced anti-serpin antibody activity inhibits autoimmune inflammation in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Alzheimer's disease, autoimmunity and inflammation. The good, the bad and the ugly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

The unfolded protein response: how protein folding became a restrictive aspect for innate immunity and B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Cellular responses to endoplasmic reticulum stress and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Endoplasmic reticulum stress in the kidney as a novel mediator of kidney injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Myofiber stress-response in myositis: parallel investigations on patients and experimental animal models of muscle regeneration and systemic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Defining the mechanism of polymerization in the serpinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z alpha 1-antitrypsin deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Neuroserpin polymers activate NF-kappaB by a calcium signaling pathway that is independent of the unfolded protein response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Genes, tolerance and systemic autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

In Sjögren's syndrome, B lymphocytes induce epithelial cells of salivary glands into apoptosis through protein kinase C delta activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Anti-annexins autoantibodies: their role as biomarkers of autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

The role of T cell apoptosis in nervous system autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

The kaleidoscope of glucorticoid effects on immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Autoantibodies to intracellular antigens: generation and pathogenetic role.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Genes, epigenetic regulation and environmental factors: which is the most relevant in developing autoimmune diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Autoantibodies in lupus: culprits or passive bystanders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Antigen Processing for MHC Class II Presentation via Autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Antigen processing via autophagy--not only for MHC class II presentation anymore?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Multiple regulatory and effector roles of autophagy in immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Peripheral B cell abnormalities and disease activity in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Peripheral B cell abnormalities in patients with systemic lupus erythematosus in quiescent phase: decreased memory B cells and membrane CD19 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Human Ovalbumin Serpin Evolution: Phylogenic Analysis, Gene Organization, and Identification of New PI8-Related Genes Suggest That Two Interchromosomal and Several Intrachromosomal Duplications Generated the Gene Clusters at 18q21–q23 and 6p25

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Comparison of Human Chromosome 6p25 with Mouse Chromosome 13 Reveals a Greatly Expanded Ov-Serpin Gene Repertoire in the Mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-013-8353-3

Autophagy eliminates a specific species of misfolded procollagen and plays a protective role in cell survival against ER stress

21 January 2018

1 reference

12 December 2020

The ovalbumin family of serpin proteins

1 reference

12 December 2020

Tumor necrosis factor-alpha stimulates the production of squamous cell carcinoma antigen in normal squamous cells

1 reference

12 December 2020

The efficiency of the uncleaved secretion signal in the plasminogen activator inhibitor type 2 protein can be enhanced by point mutations that increase its hydrophobicity

1 reference

12 December 2020

Squamous cellular carcinoma immunocomplexed is increased in scleroderma patients with lung fibrosis

1 reference

12 December 2020

Biology and facultative secretion of plasminogen activator inhibitor-2

1 reference

12 December 2020

Immunoregulatory disorders associated with hereditary angioedema. II. Serologic and cellular abnormalities

1 reference

12 December 2020

Serpin Inhibition Mechanism: A Delicate Balance between Native Metastable State and Polymerization.

1 reference

12 December 2020

A new type of acquired C1 inhibitor deficiency associated with systemic lupus erythematosus

1 reference

12 December 2020

Secondary systemic lupus erythematosus: an analysis of 4 cases of uncontrolled hereditary angioedema

1 reference

12 December 2020

Novel peptides as potential treatment of systemic lupus erythematosus

1 reference

12 December 2020

Identification of interaction between PAI-2 and IRF-3.

1 reference

12 December 2020

Angioedema and systemic lupus erythematosus--a complementary association?

1 reference

12 December 2020

Serum level of squamous cell carcinoma antigen as a new indicator of disease activity in patients with psoriasis

1 reference

12 December 2020

10.1007/S12016-013-8353-3

Identifiers

DOI

1 reference

Dimensions Publication ID

28 August 2017

1004120297

0 references

1 reference