(Q38075445)

28 August 2017

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title

Dynamic single-cell measurements of gene expression in primary lymphocytes: challenges, tools and prospects (English)

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28 August 2017

Michal Polonsky

1

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28 August 2017

Irina Zaretsky

series ordinal

2

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28 August 2017

Nir Friedman

series ordinal

3

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28 August 2017

publication date

17 January 2013

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Briefings in functional genomics

28 August 2017

published in

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28 August 2017

volume

12

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28 August 2017

issue

2

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28 August 2017

page(s)

99-108

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Transcription of individual genes in eukaryotic cells occurs randomly and infrequently

28 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

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21 January 2018

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Protein dynamics in individual human cells: experiment and theory

21 January 2018

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A stochastic single-molecule event triggers phenotype switching of a bacterial cell

21 January 2018

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Noise in gene expression: origins, consequences, and control

21 January 2018

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Stochastic gene expression in a single cell

21 January 2018

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Generation of double-labeled reporter cell lines for studying co-dynamics of endogenous proteins in individual human cells

21 January 2018

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CD4 T cells: fates, functions, and faults

21 January 2018

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Differentiation of effector CD4 T cell populations (*)

21 January 2018

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Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells

21 January 2018

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The art of the probable: system control in the adaptive immune system

21 January 2018

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Heterogeneity of single cell cytokine gene expression in clonal T cell populations

21 January 2018

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Decision-making by the immune response.

21 January 2018

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Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells

21 January 2018

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Helper T cell subsets: heterogeneity, functions and development

21 January 2018

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Two-photon imaging of lymphocyte motility and antigen response in intact lymph node

21 January 2018

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A synaptic basis for paracrine interleukin-2 signaling during homotypic T cell interaction

21 January 2018

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21 January 2018

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Poly(dimethylsiloxane) as a material for fabricating microfluidic devices

21 January 2018

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Microfabricated polyester conical microwells for cell culture applications.

21 January 2018

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Single-cell microarray for analyzing cellular response.

21 January 2018

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A microengraving method for rapid selection of single cells producing antigen-specific antibodies

21 January 2018

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Polymer live-cell array for real-time kinetic imaging of immune cells

21 January 2018

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Large-scale single-cell trapping and imaging using microwell arrays

21 January 2018

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Monitoring the dynamics of primary T cell activation and differentiation using long term live cell imaging in microwell arrays

21 January 2018

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Cell patterning chip for controlling the stem cell microenvironment

21 January 2018

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Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving

21 January 2018

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Screening individual hybridomas by microengraving to discover monoclonal antibodies

21 January 2018

1 reference

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Concurrent detection of secreted products from human lymphocytes by microengraving: cytokines and antigen-reactive antibodies

21 January 2018

1 reference

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Polyfunctional responses by human T cells result from sequential release of cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Massively parallel detection of gene expression in single cells using subnanolitre wells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

The selection of high-producing cell lines using flow cytometry and cell sorting

21 January 2018

1 reference

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A high-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis

21 January 2018

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Activation-induced B cell fates are selected by intracellular stochastic competition.

21 January 2018

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https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

A new regulatory region of the IL-2 locus that confers position-independent transgene expression

21 January 2018

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On the stochastic regulation of interleukin-2 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Independent and epigenetic regulation of the interleukin-4 alleles in CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

A single-cell pedigree analysis of alternative stochastic lymphocyte fates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

A cell chip for sequential imaging of individual non-adherent live cells reveals transients and oscillations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Imaging immune surveillance of individual natural killer cells confined in microwell arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

A method for prolonged imaging of motile lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Microwell devices with finger-like channels for long-term imaging of HIV-1 expression kinetics in primary human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Regulation of noise in the expression of a single gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Faithful activation of an extra-bright red fluorescent protein in "knock-in" Cre-reporter mice ideally suited for lineage tracing studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Stochasticity and spatial heterogeneity in T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Interleukin-2 transcription is regulated in vivo at the level of coordinated binding of both constitutive and regulated factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Probabilistic regulation in TH2 cells accounts for monoallelic expression of IL-4 and IL-13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Stochastic monoallelic expression of IL-10 in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Stochastic protein expression in individual cells at the single molecule level

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

Evidence for the stochastic acquisition of cytokine profile by CD4+ T cells activated in a T helper type 2-like responsein vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELS061

21 January 2018

Identifiers

DOI

10.1093/BFGP/ELS061

1 reference

28 August 2017

1 reference