(Q38083249)

28 August 2017

Protein organic chemistry and applications for labeling and engineering in live-cell systems (English)

1 reference

28 August 2017

Yousuke Takaoka

1

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28 August 2017

Akio Ojida

series ordinal

2

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28 August 2017

Itaru Hamachi

series ordinal

3

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28 August 2017

language of work or name

English

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publication date

20 February 2013

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Angewandte Chemie International Edition

28 August 2017

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volume

52

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28 August 2017

15

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28 August 2017

4088-4106

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Specific chemical modification of proteins

28 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Bioorthogonal chemistry: fishing for selectivity in a sea of functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Arming antibodies: prospects and challenges for immunoconjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Transition metal catalyzed methods for site-selective protein modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Die Erweiterung des genetischen Codes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Non-canonical amino acids in protein engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Reductive alkylation of proteins using iridium catalyzed transfer hydrogenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

A submicrogram-scale protocol for biomolecule-based PET imaging by rapid 6pi-azaelectrocyclization: visualization of sialic acid dependent circulatory residence of glycoproteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Facile conversion of cysteine and alkyl cysteines to dehydroalanine on protein surfaces: versatile and switchable access to functionalized proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Olefin cross-metathesis on proteins: investigation of allylic chalcogen effects and guiding principles in metathesis partner selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Toward a general chemical method for rapidly mapping multi-protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Techniques: Oxidative cross-linking as an emergent tool for the analysis of receptor-mediated signalling events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

A three-component Mannich-type reaction for selective tyrosine bioconjugation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Tyrosine-selective protein alkylation using pi-allylpalladium complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Selective tryptophan modification with rhodium carbenoids in aqueous solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Chemoselective Tryptophan Labeling with Rhodium Carbenoids at Mild pH

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Effect of pegylation on pharmaceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Chemistry for peptide and protein PEGylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

PEGylation, successful approach to drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Fluorescence ratio imaging of cyclic AMP in single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Recent progress in strategies for the creation of protein-based fluorescent biosensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Periplasmic binding proteins: a versatile superfamily for protein engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

The rational design of allosteric interactions in a monomeric protein and its applications to the construction of biosensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Construction of a fluorescent biosensor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Novel real-time sensors to quantitatively assess in vivo inositol 1,4,5-trisphosphate production in intact cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

An in vivo fluorescent sensor reveals intracellular ins(1,3,4,5)P4 dynamics in single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Activation of endogenous Cdc42 visualized in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Solvent-sensitive dyes to report protein conformational changes in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

A new screening assay for allosteric inhibitors of cSrc

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Stochastic sensors inspired by biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Choosing an effective protein bioconjugation strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Dual-surface modification of the tobacco mosaic virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Self-assembling light-harvesting systems from synthetically modified tobacco mosaic virus coat proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Expanding the diversity of chemical protein modification allows post-translational mimicry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Allosteric control of an ionotropic glutamate receptor with an optical switch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Optogenetic dissection of a behavioural module in the vertebrate spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

High-efficiency labeling of sialylated glycoproteins on living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Site-specific orthogonal labeling of the carboxy terminus of alpha-tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Live cell labeling of native intracellular bacterial receptors using aniline-catalyzed oxime ligation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Introducing genetically encoded aldehydes into proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Cell surface engineering by a modified Staudinger reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Chemical remodelling of cell surfaces in living animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Second-generation difluorinated cyclooctynes for copper-free click chemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

A BODIPY-cyclooctyne for protein imaging in live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

In vivo imaging of membrane-associated glycans in developing zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Copper-free click chemistry in living animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

N-terminal labeling of proteins by the Pictet-Spengler reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Design and synthesis of highly reactive dienophiles for the tetrazine-trans-cyclooctene ligation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

A bioorthogonal quadricyclane ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Site-specific protein modifications through pyrroline-carboxy-lysine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Selective functionalization of a genetically encoded alkene-containing protein via "photoclick chemistry" in bacterial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Selective labeling of living cells by a photo-triggered click reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

A general method for the covalent labeling of fusion proteins with small molecules in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

An engineered protein tag for multiprotein labeling in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

HaloTag: a novel protein labeling technology for cell imaging and protein analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

HaloTag7: a genetically engineered tag that enhances bacterial expression of soluble proteins and improves protein purification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

A fluorophore ligase for site-specific protein labeling inside living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Sortagging: a versatile method for protein labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Site-specific protein modification on living cells catalyzed by Sortase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Overexpression and mislocalization of a tail-anchored GFP redefines the identity of peroxisomal ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Specific covalent labeling of recombinant protein molecules inside live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Multicolor and electron microscopic imaging of connexin trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Genetically targeted chromophore-assisted light inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Calcium Green FlAsH as a genetically targeted small-molecule calcium indicator

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Label transfer chemistry for the characterization of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

From the test tube to the cell: exploring the folding and aggregation of a beta-clam protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Transgenically encoded protein photoinactivation (FlAsH-FALI): acute inactivation of synaptotagmin I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Reversible site-selective labeling of membrane proteins in live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Specific and stable fluorescence labeling of histidine-tagged proteins for dissecting multi-protein complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

A hexahistidine-Zn2+-dye label reveals STIM1 surface exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Site-specific covalent labeling of His-tag fused proteins with a reactive Ni(II)-NTA probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Selective recognition of protein tetraserine motifs with a cell-permeable, pro-fluorescent bis-boronic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Oligo-Asp tag/Zn(II) complex probe as a new pair for labeling and fluorescence imaging of proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Non-enzymatic covalent protein labeling using a reactive tag.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Selective covalent labeling of tag-fused GPCR proteins on live cell surface with a synthetic probe for their functional analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Photo-affinity labeling of specific acetylcholine-binding sites on membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Photoaffinity Labeling of Biological Systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Aliphatic diazirines as photoaffinity probes for proteins: recent developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Mechanism-based profiling of enzyme families

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Tagging and detection strategies for activity-based proteomics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Reactivity of functional groups on the protein surface: development of epoxide probes for protein labeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Fluorescent derivatives of diphenyl [1-(N-peptidylamino)alkyl]phosphonate esters: synthesis and use in the inhibition and cellular localization of serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Activity-based protein profiling: the serine hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Profiling enzyme activities in vivo using click chemistry methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Potent and selective inhibitors of glutathione S-transferase omega 1 that impair cancer drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Dynamic imaging of protease activity with fluorescently quenched activity-based probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Activity-based probes for the proteomic profiling of metalloproteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Functional interrogation of the kinome using nucleotide acyl phosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Design and synthesis of class-selective activity probes for protein tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Design and synthesis of activity probes for glycosidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Developing photoactive affinity probes for proteomic profiling: hydroxamate-based probes for metalloproteases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Double-modification of lectin using two distinct chemistries for fluorescent ratiometric sensing and imaging saccharides in test tube or in cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

One-pot and sequential organic chemistry on an enzyme surface to tether a fluorescent probe at the proximity of the active site with restoring enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Affinity-labeling-based introduction of a reactive handle for natural protein modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Ligand-directed tosyl chemistry for protein labeling in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Quenched ligand-directed tosylate reagents for one-step construction of turn-on fluorescent biosensors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Native FKBP12 engineering by ligand-directed tosyl chemistry: labeling properties and application to photo-cross-linking of protein complexes in vitro and in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

A small molecule that binds to an ATPase domain of Hsc70 promotes membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Phosphopeptide-dependent labeling of 14-3-3 ζ proteins by fusicoccin-based fluorescent probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Marinopyrrole A target elucidation by acyl dye transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Target-specific chemical acylation of lectins by ligand-tethered DMAP catalysts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Convenient modular method for affinity labeling (MoAL method) based on a catalytic amidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Catalytic protein modification with dirhodium metallopeptides: specificity in designed and natural systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Far-field optical nanoscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Imaging intracellular fluorescent proteins at nanometer resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Red-emitting rhodamine dyes for fluorescence microscopy and nanoscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Rhodamines NN: A Novel Class of Caged Fluorescent Dyes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

Site-Specific Protein Modification with a Dirhodium Metallopeptide Catalyst

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201207089

21 January 2018

Identifiers

DOI

10.1002/ANIE.201207089

1 reference

28 August 2017

1 reference