(Q38088106)

28 August 2017

The roles of senescence and telomere shortening in cardiovascular disease (English)

1 reference

28 August 2017

cardiovascular disease

1 reference

3

Timo Strandberg

1 reference

28 August 2017

Frej Fyhrquist

1

1 reference

PubMed ID

23478256

28 August 2017

Outi Saijonmaa

series ordinal

2

1 reference

PubMed ID

23478256

28 August 2017

language of work or name

English

0 references

publication date

12 March 2013

1 reference

Nature Reviews Cardiology

28 August 2017

1 reference

28 August 2017

10

1 reference

28 August 2017

5

1 reference

28 August 2017

274-283

1 reference

Cellular senescence, vascular disease, and aging: Part 1 of a 2-part review

28 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Healthy aging and disease: role for telomere biology?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Aging and atherosclerosis: mechanisms, functional consequences, and potential therapeutics for cellular senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Is telomere length a biomarker of aging? A review

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Is telomere length a biomarker for aging: cross-sectional evidence from the west of Scotland?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere shortening in atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Biological ageing and cardiovascular disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomeres and human disease: ageing, cancer and beyond

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Human cell senescence as a DNA damage response.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Cellular senescence: putting the paradoxes in perspective

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Cellular senescence in vivo: its relevance in ageing and cardiovascular disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: effects of telomerase and oxidative stress.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length and replicative aging in human vascular tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere attrition of the human abdominal aorta: relationships with age and atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Age dependent aneuploidy and telomere length of the human vascular endothelium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Short telomeres are associated with increased carotid atherosclerosis in hypertensive subjects.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Circulating leukocyte and carotid atherosclerotic plaque telomere length: interrelation, association with plaque characteristics, and restenosis after endarterectomy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length in vascular tissues from patients with atherosclerotic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Aging enhances the sensitivity of endothelial cells toward apoptotic stimuli: important role of nitric oxide

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Mechanisms involved in the aging-induced vascular dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Switching and signaling at the telomere

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length, stem cells and aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Shelterin: the protein complex that shapes and safeguards human telomeres

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Evolution of CST function in telomere maintenance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Alternative lengthening of telomeres: models, mechanisms and implications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Senescence and immortalization: role of telomeres and telomerase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Senescence Induced by Altered Telomere State, Not Telomere Loss

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

A three-state model of telomere control over human proliferative boundaries

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Conditional telomerase induction causes proliferation of hair follicle stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

An updated overview on Wnt signaling pathways: a prelude for more

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Genetic variation, nucleotide diversity, and linkage disequilibrium in seven telomere stability genes suggest that these genes may be under constraint

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Intensive meditation training, immune cell telomerase activity, and psychological mediators

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

The epigenetic regulation of mammalian telomeres

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Impartial comparative analysis of measurement of leukocyte telomere length/DNA content by Southern blots and qPCR.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length in cardiovascular disease: new challenges in measuring this marker of cardiovascular aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length and mortality: a study of leukocytes in elderly Danish twins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length and progression of diabetic nephropathy in patients with type 1 diabetes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Does a sentinel or a subset of short telomeres determine replicative senescence?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Beyond average: potential for measurement of short telomeres.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Genetics of leukocyte telomere length and its role in atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Common variants near TERC are associated with mean telomere length

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Dyskeratosis congenita, stem cells and telomeres

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

31 March 2020

The telomere syndromes

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Franklin H. Epstein Lecture: Sirtuins, aging, and medicine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length is associated with ACE I/D polymorphism in hypertensive patients with left ventricular hypertrophy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Leukocyte telomere dynamics and human hematopoietic stem cell kinetics during somatic growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length in small-for-gestational-age babies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Low birth weight is associated with altered immune function in rural Bangladeshi children: a birth cohort study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

No association between body size at birth and leucocyte telomere length in adult life--evidence from three cohort studies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length in the newborn

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Oxidative stress shortens telomeres

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length and cardiovascular risk factors in a middle-aged population free of overt cardiovascular disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length in old age and cholesterol across the life course.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Obesity, cigarette smoking, and telomere length in women

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Association of telomere length in older men with mortality and midlife body mass index and smoking

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Cigarette smoke extract induces oxidative stress and apoptosis in human lung fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Stress-induced senescence predominates in endothelial cells isolated from atherosclerotic chronic smokers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Association between alcohol consumption in healthy midlife and telomere length in older men. The Helsinki Businessmen Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Ethanol-induced oxidative stress: basic knowledge

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Accelerated telomere shortening in response to life stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Childhood adversities are associated with shorter telomere length at adult age both in individuals with an anxiety disorder and controls

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomeres and lifestyle factors: roles in cellular aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Multivitamin use and telomere length in women

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

The Association Between Physical Activity in Leisure Time and Leukocyte Telomere Length

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Association between telomere length, specific causes of death, and years of healthy life in health, aging, and body composition, a population-based cohort study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Physical fitness and telomere length in patients with coronary heart disease: findings from the Heart and Soul Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Increased telomerase activity and comprehensive lifestyle changes: a pilot study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

The immortal strand hypothesis: segregation and reconstruction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomerase regulation and stem cell behaviour

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Synchrony of telomere length among hematopoietic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Can Critically Short Telomeres Cause Functional Exhaustion of Progenitor Cells in Postinfarction Heart Failure?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere gap between granulocytes and lymphocytes is a determinant for hematopoetic progenitor cell impairment in patients with previous myocardial infarction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Life and death of cardiac stem cells: a paradigm shift in cardiac biology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Evidence for cardiomyocyte renewal in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Blood cell telomere length is a dynamic feature

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere biology in cardiovascular disease: the TERC-/- mouse as a model for heart failure and ageing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Mouse Models of Atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Mouse models for atherosclerosis and pharmaceutical modifiers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Short telomeres protect from diet-induced atherosclerosis in apolipoprotein E-null mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

The role of vascular cell senescence in atherosclerosis: antisenescence as a novel therapeutic strategy for vascular aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Vascular cell senescence: contribution to atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere attrition and accumulation of senescent cells in cultured human endothelial cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomerase activity in rat cardiac myocytes is age and gender dependent

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

The telomere-telomerase axis and the heart

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

RETRACTED: Cardiomyogenesis in the aging and failing human heart

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Medicine. Cardiac regeneration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere Length of Circulating Leukocytes Is Decreased in Patients With Chronic Heart Failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomeres and mitochondria in the aging heart

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Return to the fetal gene program protects the stressed heart: a strong hypothesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

The failing heart--an engine out of fuel

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Leukocyte telomere length and carotid artery intimal medial thickness: the Framingham Heart Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

White cell telomere length and risk of premature myocardial infarction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Prognostic value of leukocyte telomere length in patients with stable coronary artery disease: data from the Heart and Soul Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length inversely correlates with pulse pressure and is highly familial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: the LIFE study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length and risk of stroke in Chinese.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Relative leukocyte telomere length and risk of incident ischemic stroke in men: a prospective, nested case-control approach

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length is shorter in healthy offspring of subjects with coronary artery disease: support for the telomere hypothesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomere length of circulating leukocyte subpopulations and buccal cells in patients with ischemic heart failure and their offspring

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

No shorter telomeres in subjects with a family history of cardiovascular disease in the Asklepios study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Cellular senescence in endothelial cells from atherosclerotic patients is accelerated by oxidative stress associated with cardiovascular risk factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Vascular endothelial ageing, heartbeat after heartbeat

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Endogenous oxidative stress prevents telomerase-dependent immortalization of human endothelial cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Angiotensin II accelerates endothelial progenitor cell senescence through induction of oxidative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Telomerase and cancer therapeutics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2013.30

Change of telomere length in angiotensin II-induced human glomerular mesangial cell senescence and the protective role of losartan.

31 March 2020

1 reference

12 December 2020

Estrogen activates telomerase.

1 reference

12 December 2020

Cellular senescence: a link between cancer and age-related degenerative disease?

1 reference

12 December 2020

Cellular senescence, vascular disease, and aging: part 2 of a 2-part review: clinical vascular disease in the elderly

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRCARDIO.2013.30

1 reference

28 August 2017

1 reference

PubMed ID

23478256