(Q38089232)

English

Review: cerebral amyloid angiopathy, prion angiopathy, CADASIL and the spectrum of protein elimination failure angiopathies (PEFA) in neurodegenerative disease with a focus on therapy

scientific article published on October 2013

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scholarly article

1 reference

Europe PubMed Central

28 August 2017

Review: cerebral amyloid angiopathy, prion angiopathy, CADASIL and the spectrum of protein elimination failure angiopathies (PEFA) in neurodegenerative disease with a focus on therapy (English)

1 reference

Europe PubMed Central

28 August 2017

prion protein family

0 references

neurodegeneration

1 reference

based on heuristic

inferred from title

cerebral amyloid angiopathy

1 reference

based on heuristic

inferred from title

author name string

R O Carare

1

1 reference

Europe PubMed Central

28 August 2017

C A Hawkes

2

1 reference

Europe PubMed Central

28 August 2017

M Jeffrey

3

1 reference

Europe PubMed Central

28 August 2017

R N Kalaria

4

1 reference

Europe PubMed Central

28 August 2017

R O Weller

5

1 reference

Europe PubMed Central

28 August 2017

publication date

1 October 2013

1 reference

Europe PubMed Central

28 August 2017

Neuropathology and Applied Neurobiology

1 reference

Europe PubMed Central

28 August 2017

39

1 reference

Europe PubMed Central

28 August 2017

6

1 reference

Europe PubMed Central

28 August 2017

593-611

1 reference

Europe PubMed Central

28 August 2017

Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Evidence for a 'paravascular' fluid circulation in the mammalian central nervous system, provided by the rapid distribution of tracer protein throughout the brain from the subarachnoid space

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Pathophysiology of the lymphatic drainage of the central nervous system: Implications for pathogenesis and therapy of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Migration of monocytes after intracerebral injection at entorhinal cortex lesion site.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Intracerebral immune complex formation induces inflammation in the brain that depends on Fc receptor interaction

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Lymphatic drainage of the brain and the pathophysiology of neurological disease

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Trafficking of glucose, lactate, and amyloid-beta from the inferior colliculus through perivascular routes

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Intrastriatal convection-enhanced delivery results in widespread perivascular distribution in a pre-clinical model

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Directional and compartmentalised drainage of interstitial fluid and cerebrospinal fluid from the rat brain

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Mechanisms to explain the reverse perivascular transport of solutes out of the brain.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Cholinergic deafferentation of the rabbit cortex: a new animal model of Abeta deposition

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Astrocytes as a source for extracellular matrix molecules and cytokines

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Mechanism of cerebral beta-amyloid angiopathy: murine and cellular models

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Extracellular deposits of A beta produced in cultures of Alzheimer disease brain vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Novel diagnostic features of dysferlinopathies

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Abeta-degrading enzymes in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Dutch, Flemish, Italian, and Arctic mutations of APP and resistance of Abeta to physiologically relevant proteolytic degradation.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

The cerebral beta-amyloid angiopathies: hereditary and sporadic

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Transcranial doppler ultrasound blood flow velocity and pulsatility index as systemic indicators for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Aging is associated with increased collagen type IV accumulation in the basal lamina of human cerebral microvessels

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Type IV collagen prevents amyloid beta-protein fibril formation

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Laminin inhibits amyloid-beta-peptide fibrillation.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Laminin inhibition of beta-amyloid protein (Abeta) fibrillogenesis and identification of an Abeta binding site localized to the globular domain repeats on the laminin a chain

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Capillary cerebral amyloid angiopathy identifies a distinct APOE epsilon4-associated subtype of sporadic Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Production and increased detection of amyloid beta protein and amyloidogenic fragments in brain microvessels, meningeal vessels and choroid plexus in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Beta-amyloid formation by myocytes of leptomeningeal vessels

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Consequence of Abeta immunization on the vasculature of human Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Distinct profiles of PrPd immunoreactivity in the brain of scrapie- and BSE-infected sheep: implications for differential cell targeting and PrP processing

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Cellular and sub-cellular pathology of animal prion diseases: relationship between morphological changes, accumulation of abnormal prion protein and clinical disease

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Classical sheep transmissible spongiform encephalopathies: pathogenesis, pathological phenotypes and clinical disease

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Familial prion disease with Alzheimer disease-like tau pathology and clinical phenotype

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Prion protein amyloidosis with divergent phenotype associated with two novel nonsense mutations in PRNP.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Fatal transmissible amyloid encephalopathy: a new type of prion disease associated with lack of prion protein membrane anchoring

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Determination of the frequency and distribution of vascular and parenchymal amyloid with polyclonal and N-terminal-specific PrP antibodies in scrapie-affected sheep and mice.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Non-amyloid and amyloid prion protein deposits in prion-infected mice differ in blockage of interstitial brain fluid

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Anchorless prion protein results in infectious amyloid disease without clinical scrapie

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Recombinant prion protein induces a new transmissible prion disease in wild-type animals

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Genesis of mammalian prions: from non-infectious amyloid fibrils to a transmissible prion disease

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

A new mechanism for transmissible prion diseases

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Exogenous induction of cerebral beta-amyloidosis in betaAPP-transgenic mice.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Neuroinvasion in sheep transmissible spongiform encephalopathies: the role of the haematogenous route.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Review: molecular genetics and pathology of hereditary small vessel diseases of the brain.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

CADASIL-causing mutations do not alter Notch3 receptor processing and activation

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Impaired vascular mechanotransduction in a transgenic mouse model of CADASIL arteriopathy

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Migraine aura pathophysiology: the role of blood vessels and microembolisation

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Cortical neuronal apoptosis in CADASIL.

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Mutations in NOTCH3 cause the formation and retention of aggregates in the endoplasmic reticulum, leading to impaired cell proliferation

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Hereditary cystatin C amyloid angiopathy: genetic, clinical, and pathological aspects

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Notch3 ectodomain is a major component of granular osmiophilic material (GOM) in CADASIL

1 reference

https://api.crossref.org/works/10.1111%2FNAN.12042

21 January 2018

Identifiers

10.1111/NAN.12042

1 reference

Europe PubMed Central

28 August 2017

1 reference

Europe PubMed Central

28 August 2017

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