(Q38091646)

28 August 2017

title

Biosynthesis and pathway engineering of antifungal polyene macrolides in actinomycetes (English)

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28 August 2017

Dekun Kong

1

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28 August 2017

Mi-Jin Lee

series ordinal

2

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28 August 2017

Shuangjun Lin

series ordinal

3

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28 August 2017

Eung-Soo Kim

series ordinal

4

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28 August 2017

language of work or name

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21 March 2013

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Journal of Industrial Microbiology & Biotechnology

28 August 2017

published in

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28 August 2017

volume

40

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28 August 2017

issue

6

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28 August 2017

page(s)

529-543

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To enhance dissolution rate of poorly water-soluble drugs: glucosamine hydrochloride as a potential carrier in solid dispersion formulations

28 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

PimM, a PAS domain positive regulator of pimaricin biosynthesis in Streptomyces natalensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Polyene antibiotic biosynthesis gene clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Interaction of amphotericin B and its selected derivatives with membranes: molecular modeling studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Molecular modeling of amphotericin B-ergosterol primary complex in water II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

How do the polyene macrolide antibiotics affect the cellular membrane properties?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Probing the structure-function relationship of polyene macrolides: engineered biosynthesis of soluble nystatin analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin biosynthesis in Streptomyces noursei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Improved antifungal polyene macrolides via engineering of the nystatin biosynthetic genes in Streptomyces noursei

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Chemical diversity of polyene macrolides produced by Streptomyces noursei ATCC 11455 and recombinant strain ERD44 with genetically altered polyketide synthase NysC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Biosynthesis of deoxyamphotericins and deoxyamphoteronolides by engineered strains of Streptomyces nodosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Biosynthetic engineering of polyene macrolides towards generation of improved antifungal and antiparasitic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

The candicidin gene cluster from Streptomyces griseus IMRU 3570.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Genome mining of the biosynthetic gene cluster of the polyene macrolide antibiotic tetramycin and characterization of a P450 monooxygenase involved in the hydroxylation of the tetramycin B polyol segment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Analysis and manipulation of amphotericin biosynthetic genes by means of modified phage KC515 transduction techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Tailoring the P450 monooxygenase gene for FR-008/candicidin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Organizational and mutational analysis of a complete FR-008/candicidin gene cluster encoding a structurally related polyene complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

A subfamily of MalT-related ATP-dependent regulators in the LuxR family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Amphotericin B nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Identification of a novel Streptomyces chattanoogensis L10 and enhancing its natamycin production by overexpressing positive regulator ScnRII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Amphotericin B: spectrum and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Candicidin biosynthesis in Streptomyces griseus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

21 January 2018

Antifungal antibiotics

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Initiation of polyene macrolide biosynthesis: interplay between polyketide synthase domains and modules as revealed via domain swapping, mutagenesis, and heterologous complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Redesign of polyene macrolide glycosylation: engineered biosynthesis of 19-(O)-perosaminyl-amphoteronolide B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Analysis and functional expression of NPP pathway-specific regulatory genes in Pseudonocardia autotrophica

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Structure of Cytochrome P450 PimD Suggests Epoxidation of the Polyene Macrolide Pimaricin Occurs via a Hydroperoxoferric Intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Characterization of a regulatory gene, aveR, for the biosynthesis of avermectin in Streptomyces avermitilis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Discovery of a pimaricin analog JBIR-13, from Streptomyces bicolor NBRC 12746 as predicted by sequence analysis of type I polyketide synthase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Synthesis and macrophage activation of lentinan-mimic branched amino polysaccharides: curdlans having N-Acetyl-d-glucosamine branches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Structural analysis and biosynthetic engineering of a solubility-improved and less-hemolytic nystatin-like polyene in Pseudonocardia autotrophica.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Functional characterization and transcriptional analysis of the dnrR1 locus, which controls daunorubicin biosynthesis in Streptomyces peucetius

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Phosphate control of the biosynthesis of antibiotics and other secondary metabolites is mediated by the PhoR-PhoP system: an unfinished story

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Enzymology of the polyenes pimaricin and candicidin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Transcriptomic studies of phosphate control of primary and secondary metabolism in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

The two-component phoR-phoP system of Streptomyces natalensis: Inactivation or deletion of phoP reduces the negative phosphate regulation of pimaricin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Engineered biosynthesis of novel polyenes: a pimaricin derivative produced by targeted gene disruption in Streptomyces natalensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Isolation and characterisation of amphotericin B analogues and truncated polyketide intermediates produced by genetic engineering of Streptomyces nodosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Nucleotide sequence and transcriptional analysis of the redD locus of Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Analysis of the mycosamine biosynthesis and attachment genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Liposomal polyene antibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Phosphomannose isomerase and phosphomannomutase gene disruptions in Streptomyces nodosus: impact on amphotericin biosynthesis and implications for glycosylation engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Current status and future of antifungal therapy for systemic mycoses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Leishmaniasis: drugs in the clinic, resistance and new developments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Stereostructure of Perimycin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

New ventures in the chemistry of avermectins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Engineered synthesis of 7-oxo- and 15-deoxy-15-oxo-amphotericins: insights into structure-activity relationships in polyene antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Functional conservation of PAS-LuxR transcriptional regulators in polyene macrolide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Hierarchical control on polyene macrolide biosynthesis: PimR modulates pimaricin production via the PAS-LuxR transcriptional activator PimM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Starter unit choice determines the production of two tetraene macrolides, rimocidin and CE-108, in Streptomyces diastaticus var. 108.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

MFAME, N-methyl-N-D-fructosyl amphotericin B methyl ester, a new amphotericin B derivative of low toxicity: relationship between self-association and effects on red blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Polyene antibiotic that inhibits membrane transport proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Amphotericin B formulations and drug targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Characterization of the P450 monooxygenase NysL, responsible for C-10 hydroxylation during biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Solution NMR structure of five representative glycosylated polyene macrolide antibiotics with a sterol-dependent antifungal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Characterization and analysis of the PikD regulatory factor in the pikromycin biosynthetic pathway of Streptomyces venezuelae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

The in vitro characterization of polyene glycosyltransferases AmphDI and NysDI

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Functional characterization of the first two actinomycete 4-amino-4-deoxychorismate lyase genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Genetic analysis of nystatin and amphotericin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

Polyene macrolide antibiotics and their applications in human therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1258-6

The structure of nystatin A3, a component of nystatin complex

21 January 2018

1 reference

12 December 2020

Control of antibiotic biosynthesis

1 reference

12 December 2020

Nutritional control of actinorhodin production by Streptomyces coelicolor A3(2): suppressive effects of nitrogen and phosphate

1 reference

12 December 2020

Effect of the modifications of ionizable groups of amphotericin B on its ability to form complexes with sterols in hydroalcoholic media

1 reference

12 December 2020

The action of pimaricin, etruscomycin and amphotericin B on liposomes with varying sterol content

1 reference

12 December 2020

Development of liposomal polyene antibiotics: an historical perspective

1 reference

12 December 2020

[Comparative analysis of in vitro antifungal activity and in vivo acute toxicity of the nystatin analogue S44HP produced via genetic engineering]

1 reference

12 December 2020

Characterization of the pathway-specific positive transcriptional regulator for actinorhodin biosynthesis in Streptomyces coelicolor A3(2) as a DNA-binding protein

1 reference

12 December 2020

Enzymatic glycosylation of nonbenzoquinone geldanamycin analogs via Bacillus UDP-glycosyltransferase.

1 reference

12 December 2020

Streptomyces nodosus host strains optimized for polyene glycosylation engineering

1 reference

12 December 2020

A novel injectable water-soluble amphotericin B-arabinogalactan conjugate

1 reference

12 December 2020

10.1007/S10295-013-1258-6

Identifiers

DOI

1 reference

release_hkmcqxe2yfebphq3tqhxee22ci

28 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hkmcqxe2yfebphq3tqhxee22ci

24 November 2022

mapped directly with Wikidata item

1 reference