(Q38628127)

English

Initiation of polyene macrolide biosynthesis: interplay between polyketide synthase domains and modules as revealed via domain swapping, mutagenesis, and heterologous complementation

scientific article published on 05 August 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Initiation of polyene macrolide biosynthesis: interplay between polyketide synthase domains and modules as revealed via domain swapping, mutagenesis, and heterologous complementation (English)

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

author name string

Sondre Heia

1

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Sven E F Borgos

2

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Håvard Sletta

3

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Leticia Escudero

4

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Elena M Seco

5

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Francisco Malpartida

6

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Trond E Ellingsen

7

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Sergey B Zotchev

8

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

language of work or name

0 references

publication date

5 August 2011

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Applied and Environmental Microbiology

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

77

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

19

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

6982-6990

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

6 September 2017

Two polyene amides produced by genetically modified Streptomyces diastaticus var. 108.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

6 September 2017

Genetic approaches to polyketide antibiotics. 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

6 September 2017

Polyketide biosynthesis: understanding and exploiting modularity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

6 September 2017

Polyene antibiotic biosynthesis gene clusters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

6 September 2017

Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

6 September 2017

Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

6 September 2017

Role of crotonyl coenzyme A reductase in determining the ratio of polyketides monensin A and monensin B produced by Streptomyces cinnamonensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

6 September 2017

Initiation, elongation, and termination strategies in polyketide and polypeptide antibiotic biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

6 September 2017

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

6 September 2017

Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

14 September 2017

Chemical diversity of polyene macrolides produced by Streptomyces noursei ATCC 11455 and recombinant strain ERD44 with genetically altered polyketide synthase NysC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

14 September 2017

In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

14 September 2017

Starter unit choice determines the production of two tetraene macrolides, rimocidin and CE-108, in Streptomyces diastaticus var. 108.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

23 June 2018

Improved antifungal polyene macrolides via engineering of the nystatin biosynthetic genes in Streptomyces noursei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

31 August 2018

Identification of the sequences involved in the glucose-repressed transcription of the Streptomyces halstedii JM8 xysA promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

31 August 2018

Structure-based mutagenesis of the malonyl-CoA:acyl carrier protein transacylase from Streptomyces coelicolor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

31 August 2018

Active-site residue, domain and module swaps in modular polyketide synthases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

31 August 2018

Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin biosynthesis in Streptomyces noursei.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

31 August 2018

Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

31 August 2018

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

31 August 2018

Molecular cloning and analysis of a pleiotropic regulatory gene locus from the nystatin producer Streptomyces noursei ATCC11455.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

31 August 2018

The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

31 August 2018

Engineering broader specificity into an antibiotic-producing polyketide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187094

31 August 2018

PCR-mediated recombination and mutagenesis. SOEing together tailor-made genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21821762

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21821762

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A chain initiation factor common to both modular and aromatic polyketide synthases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21821762

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tailoring activity is responsible for generating polyene amide derivatives in Streptomyces diastaticus var. 108

1 reference

https://pubmed.ncbi.nlm.nih.gov/21821762

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CE-108, a New Macrolide Tetraene Antibiotic

1 reference

https://pubmed.ncbi.nlm.nih.gov/21821762

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Crotonyl Coenzyme A Reductase in Determining the Ratio of Polyketides Monensin A and Monensin B Produced byStreptomyces cinnamonensis

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.181.21.6806-6813.1999

Identifiers

10.1128/AEM.05781-11

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

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