(Q38097536)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23570471%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

DNA repair and cytotoxic drugs: the potential role of RAD51 in clinical outcome of non-small-cell lung cancer patients (English)

1 reference

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28 February 2020

1 reference

1

1 reference

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28 February 2020

Raquel Catarino

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23570471%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Rui Medeiros

series ordinal

4

1 reference

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28 February 2020

author name string

Joana Assis

series ordinal

2

1 reference

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28 February 2020

language of work or name

1 reference

1 April 2013

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28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23570471%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

14

1 reference

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28 February 2020

issue

6

1 reference

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28 February 2020

page(s)

689-700

1 reference

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Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

28 February 2020

cites work

1 reference

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Non-small cell lung cancer exhibits transcript overexpression of genes associated with homologous recombination and DNA replication pathways

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Optimizing chemotherapy for patients with advanced non-small cell lung cancer

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An analysis of DNA repair as a determinant of survival in patients with non-small-cell lung cancer.

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ERCC1 and ERCC2 polymorphisms predict clinical outcomes of oxaliplatin-based chemotherapies in gastric and colorectal cancer: a systemic review and meta-analysis

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Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells

21 January 2018

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XPD and XRCC1 genetic polymorphisms are prognostic factors in advanced non-small-cell lung cancer patients treated with platinum chemotherapy

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Excision repair cross-complementation group 1 polymorphism predicts overall survival in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.

21 January 2018

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ERCC1 codon 118 polymorphism is a predictive factor for the tumor response to oxaliplatin/5-fluorouracil combination chemotherapy in patients with advanced colorectal cancer.

21 January 2018

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Homologous recombination and cell cycle checkpoints: Rad51 in tumour progression and therapy resistance

21 January 2018

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Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

21 January 2018

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Gene expression in tumor-adjacent normal tissue is associated with recurrence in patients with rectal cancer treated with adjuvant chemoradiation

21 January 2018

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DNA double-strand breaks: signaling, repair and the cancer connection

21 January 2018

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Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes

21 January 2018

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Coordinated response of mammalian Rad51 and Rad52 to DNA damage

21 January 2018

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Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation

21 January 2018

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Mechanism of homologous recombination: mediators and helicases take on regulatory functions

21 January 2018

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Sensing and repairing DNA double-strand breaks

21 January 2018

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Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks

21 January 2018

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DNA double-strand break repair signalling: the case of RAD51 post-translational regulation.

21 January 2018

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Homologous recombinational repair of DNA ensures mammalian chromosome stability

21 January 2018

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Chromosome mapping of the human (RECA) and mouse (Reca) homologs of the yeast RAD51 and Escherichia coli recA genes to human (15q15.1) and mouse (2F1) chromosomes by direct R-banding fluorescence in situ hybridization.

21 January 2018

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Effects of HsRad51 overexpression on cell proliferation, cell cycle progression, and apoptosis

21 January 2018

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Homologous recombination and its regulation

21 January 2018

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Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

21 January 2018

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Regulation of DNA strand exchange in homologous recombination

21 January 2018

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Mechanism of eukaryotic homologous recombination

21 January 2018

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BRCA1 and BRCA2: 1994 and beyond

21 January 2018

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Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability

21 January 2018

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DNA repair and recombination factor Rad51 is over-expressed in human pancreatic adenocarcinoma

21 January 2018

1 reference

p53 splice acceptor site mutation and increased HsRAD51 protein expression in Bloom's syndrome GM1492 fibroblasts

21 January 2018

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The RAD51 protein supports homologous recombination by an exchange mechanism in mammalian cells

21 January 2018

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Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase

21 January 2018

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The consequences of Rad51 overexpression for normal and tumor cells

21 January 2018

1 reference

Over-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancer

21 January 2018

1 reference

Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells

21 January 2018

1 reference

In vitro and in vivo potentiation of radiosensitivity of malignant gliomas by antisense inhibition of the RAD51 gene

21 January 2018

1 reference

High-level expression of Rad51 is an independent prognostic marker of survival in non-small-cell lung cancer patients

21 January 2018

1 reference

BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance

21 January 2018

1 reference

Rad52 inactivation is synthetically lethal with BRCA2 deficiency

21 January 2018

1 reference

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

1 reference

The concept of synthetic lethality in the context of anticancer therapy

21 January 2018

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

21 January 2018

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Detection of impaired homologous recombination repair in NSCLC cells and tissues.

21 January 2018

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Involvement of Rad51 in cytotoxicity induced by epidermal growth factor receptor inhibitor (gefitinib, IressaR) and chemotherapeutic agents in human lung cancer cells.

21 January 2018

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Large-scale investigation of base excision repair genetic polymorphisms and lung cancer risk in a multicenter study

21 January 2018

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Polymorphisms in the DNA repair genes XPD, XRCC1, XRCC3, and APE/ref-1, and the risk of lung cancer among male smokers in Finland

21 January 2018

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Smoking, DNA repair capacity and risk of nonsmall cell lung cancer

21 January 2018

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The resurgence of platinum-based cancer chemotherapy

21 January 2018

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Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer

21 January 2018

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Clinical model to predict survival in chemonaive patients with advanced non-small-cell lung cancer treated with third-generation chemotherapy regimens based on eastern cooperative oncology group data

21 January 2018

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Association between polymorphisms of ERCC1 and XPD and survival in non-small-cell lung cancer patients treated with cisplatin combination chemotherapy

21 January 2018

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21 January 2018

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A single nucleotide polymorphism in the RAD51 gene modifies cancer risk in BRCA2 but not BRCA1 carriers

21 January 2018

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DNA damage and repair in gastric cancer--a correlation with the hOGG1 and RAD51 genes polymorphisms.

21 January 2018

1 reference

A single-nucleotide polymorphism in the RAD51 gene modifies breast cancer risk in BRCA2 carriers, but not in BRCA1 carriers or noncarriers

21 January 2018

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Role of CBP/P300 in nuclear receptor signalling

21 January 2018

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Polymorphisms in genes involved in homologous recombination repair interact to increase the risk of developing acute myeloid leukemia

21 January 2018

1 reference

Influence of DNA repair RAD51 gene variants in overall survival of non-small cell lung cancer patients treated with first line chemotherapy

21 January 2018

1 reference

Polymorphisms of homologous recombination genes and clinical outcomes of non-small cell lung cancer patients treated with definitive radiotherapy

21 January 2018

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Specific combinations of DNA repair gene variants and increased risk for non-small cell lung cancer.

21 January 2018

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Fusion tyrosine kinases induce drug resistance by stimulation of homology-dependent recombination repair, prolongation of G(2)/M phase, and protection from apoptosis

21 January 2018

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21 January 2018

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21 January 2018

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Polymorphisms in DNA repair genes modulate survival in cisplatin/gemcitabine-treated non-small-cell lung cancer patients

21 January 2018

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21 January 2018

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Double-Strand Break Repair Gene Polymorphisms and Risk of Breast or Ovarian Cancer

21 January 2018

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ERCC1, hRad51, and BRCA1 protein expression in relation to tumour response and survival of stage III/IV NSCLC patients treated with chemotherapy

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. . .to a future of genetic medicine

21 January 2018

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