(Q38100593)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

0 references

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

A Casazza

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

G Di Conza

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

M Wenes

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

V Finisguerra

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

S Deschoemaeker

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

English

0 references

publication date

22 April 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

issue

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

1743-1754

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2013.121

29 February 2020

exact match

0 references

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31 March 2020

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Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes

31 March 2020

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Mitochondria as signaling organelles in the vascular endothelium

31 March 2020

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Activation of the VEGFR1 chromatin domain: an angiogenic signal-ETS1/HIF-2alpha regulatory axis

31 March 2020

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HIF-2alpha specifically activates the VE-cadherin promoter independently of hypoxia and in synergy with Ets-1 through two essential ETS-binding sites

31 March 2020

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Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis

31 March 2020

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Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis.

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Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells

31 March 2020

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Hypoxia inducible factor-1α correlates with VEGF-C expression and lymphangiogenesis in breast cancer

31 March 2020

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VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours.

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis

31 March 2020

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Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy

31 March 2020

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Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis

31 March 2020

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Loss of fibroblast HIF-1α accelerates tumorigenesis.

31 March 2020

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Oxidative stress promotes myofibroblast differentiation and tumour spreading

31 March 2020

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Involvement of transforming growth factor-beta 1 signaling in hypoxia-induced tolerance to glucose starvation

31 March 2020

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Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

31 March 2020

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

31 March 2020

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HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion

31 March 2020

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Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

31 March 2020

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SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells

31 March 2020

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VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells

31 March 2020

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Anoxia-induced up-regulation of interleukin-8 in human malignant melanoma. A potential mechanism for high tumor aggressiveness

31 March 2020

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Endothelial Semaphorin 7A promotes neutrophil migration during hypoxia

31 March 2020

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Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity

31 March 2020

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Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosis

31 March 2020

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HIF-1alpha is essential for myeloid cell-mediated inflammation

31 March 2020

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THE NATURE OF LEUKEMIC BLOOD CELLS AS DETERMINED BY THEIR METABOLISM.

31 March 2020

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Hypoxia prolongs neutrophil survival in vitro

31 March 2020

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Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice

31 March 2020

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Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils.

31 March 2020

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Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN

31 March 2020

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Tumor entrained neutrophils inhibit seeding in the premetastatic lung

31 March 2020

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Neutrophils in anti-cancer immunological strategies: old players in new games

31 March 2020

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On the dual roles and polarized phenotypes of neutrophils in tumor development and progression.

31 March 2020

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Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth

31 March 2020

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Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages.

31 March 2020

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Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation

31 March 2020

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Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes

31 March 2020

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Cancer-related inflammation

31 March 2020

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Hypoxia regulates macrophage functions in inflammation.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2013.121

31 March 2020

Hypoxia and inflammation

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https://api.crossref.org/works/10.1038%2FONC.2013.121

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

31 March 2020

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FcRgamma activation regulates inflammation-associated squamous carcinogenesis.

31 March 2020

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p50 Nuclear Factor- B Overexpression in Tumor-Associated Macrophages Inhibits M1 Inflammatory Responses and Antitumor Resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia

31 March 2020

1 reference

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Regulation of the chemokine receptor CXCR4 by hypoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Knockout of HIF-1α in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

31 March 2020

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"Re-educating" tumor-associated macrophages by targeting NF-kappaB.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Arginase: an emerging key player in the mammalian immune system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Cancer: Macrophages limit chemotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

The macrophage - a novel system to deliver gene therapy to pathological hypoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Immunobiology of dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Tumor growth and angiogenesis are dependent on the presence of immature dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Hypoxia and hypoxia-inducible factor-1 alpha modulate lipopolysaccharide-induced dendritic cell activation and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Hypoxia stimulus: An adaptive immune response during dendritic cell maturation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Hypoxia affects dendritic cell survival: role of the hypoxia-inducible factor-1α and lipopolysaccharide.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2013.121

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Tumor-infiltrating B-cell-derived IgG recognizes tumor components in human lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

CD20+ B cells: the other tumor-infiltrating lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

In vivo sensitized and in vitro activated B cells mediate tumor regression in cancer adoptive immunotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1alpha -deficient chimeric mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Differentiation stage-specific requirement in hypoxia-inducible factor-1alpha-regulated glycolytic pathway during murine B cell development in bone marrow

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Innate response activator B cells protect against microbial sepsis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Reciprocal regulation of polarized cytokine production by effector B and T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Influence of tumour physico-chemical conditions on interleukin-2-stimulated lymphocyte proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

p66Shc is involved in promoting HIF-1alpha accumulation and cell death in hypoxic T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

The adaptor protein p66Shc is a positive regulator in the angiogenic response induced by hypoxic T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Metabolism in T cell activation and differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Fuel feeds function: energy metabolism and the T-cell response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Molecular pathways: hypoxia response in immune cells fighting or promoting cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Targeting natural killer cells and natural killer T cells in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Natural killer-cell activity under conditions reflective of tumor micro-environment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Natural killer cell-mediated basal and interferon-enhanced cytotoxicity against liver cancer cells is significantly impaired under in vivo oxygen conditions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

IL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Contribution of platelets to tumour metastasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

A novel role for platelet secretion in angiogenesis: mediating bone marrow-derived cell mobilization and homing.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Platelets actively sequester angiogenesis regulators

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Aspirin, salicylates, and cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Will an aspirin a day keep cancer away?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

Inhibition of platelet function: does it offer a chance of better cancer progression control?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.121

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.121

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23604130%20AND%20SRC:MED&resulttype=core&format=json