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English
Regulation where autophagy intersects the inflammasome.
scientific article published on 31 July 2013
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
title
Regulation where autophagy intersects the inflammasome
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
main subject
autophagy
0 references
inflammasome complex
1 reference
based on heuristic
inferred from title
author
Mary A Rodgers
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
author name string
James W Bowman
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Qiming Liang
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Jae U Jung
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
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29 February 2020
publication date
31 July 2013
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
published in
Antioxidants & Redox Signaling
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
volume
20
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
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29 February 2020
issue
3
1 reference
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Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
page(s)
495-506
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
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Proteolytic processing of Nlrp1b is required for inflammasome activity
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An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages
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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
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Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
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6 September 2017
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Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity
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NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways
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NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK
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NLRX1/NOD5 deficiency does not affect MAVS signalling
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VDAC, a multi-functional mitochondrial protein as a pharmacological target
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TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.
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6 September 2017
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation
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Inflammasomes and autoimmunity
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6 September 2017
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
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Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing
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6 September 2017
The complex interplay of NOD-like receptors and the autophagy machinery in the pathophysiology of Crohn disease
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6 September 2017
A role for mitochondria in NLRP3 inflammasome activation
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6 September 2017
When autophagy meets viruses: a double-edged sword with functions in defense and offense
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6 September 2017
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
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6 September 2017
The inflammasomes
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6 September 2017
Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease
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6 September 2017
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
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6 September 2017
Specificity of the BRISC deubiquitinating enzyme is not due to selective binding to Lys63-linked polyubiquitin
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6 September 2017
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
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6 September 2017
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
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6 September 2017
Recognition and processing of ubiquitin-protein conjugates by the proteasome
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6 September 2017
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans
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Mechanisms of interleukin-1beta release
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6 September 2017
K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1
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6 September 2017
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
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6 September 2017
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
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6 September 2017
Crystal Structure of Procaspase-1 Zymogen Domain Reveals Insight into Inflammatory Caspase Autoactivation
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6 September 2017
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
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MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages.
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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
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6 September 2017
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NOX enzymes and Toll-like receptor signaling.
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6 September 2017
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
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6 September 2017
NLRX1 is a regulator of mitochondrial antiviral immunity
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6 September 2017
Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation
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6 September 2017
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages
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6 September 2017
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
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6 September 2017
Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling
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6 September 2017
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
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6 September 2017
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1
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retrieved
6 September 2017
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
Role of sodium in mitochondrial membrane depolarization induced by P2X7 receptor activation in submandibular glands
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
6 September 2017
Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
14 September 2017
A key role for redox signaling in rapid P2X7 receptor-induced IL-1 beta processing in human monocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
14 September 2017
Common pathways in Crohn's disease and other inflammatory diseases revealed by genomics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
14 September 2017
Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
14 September 2017
The NLRP12 inflammasome recognizes Yersinia pestis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
28 September 2017
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
23 June 2018
Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
23 June 2018
Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
31 August 2018
Critical role of AIM2 in Mycobacterium tuberculosis infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
31 August 2018
'Nodophagy': New crossroads in Crohn disease pathogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
31 August 2018
Human NLRP3 inflammasome activation is Nox1-4 independent
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
31 August 2018
MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
31 August 2018
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
3 December 2018
Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894701
retrieved
3 December 2018
Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB Activation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23642014
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cutting edge: nitric oxide inhibits the NLRP3 inflammasome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23642014
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23642014
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nitric oxide prevents IL-1beta and IFN-gamma-inducing factor (IL-18) release from macrophages by inhibiting caspase-1 (IL-1beta-converting enzyme)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23642014
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1089/ARS.2013.5347
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PMCID
3894701
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PubMed ID
23642014
1 reference
stated in
Europe PubMed Central
PMCID
3894701
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23642014%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
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