(Q38113488)

29 August 2017

title

Long QT syndrome: beyond the causal mutation (English)

1 reference

29 August 2017

1 reference

3

Arthur A M Wilde

1 reference

29 August 2017

Ahmad S Amin

1

1 reference

29 August 2017

Yigal M Pinto

series ordinal

2

1 reference

29 August 2017

language of work or name

English

0 references

publication date

10 June 2013

1 reference

29 August 2017

published in

Journal of Physiology

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29 August 2017

volume

591

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29 August 2017

issue

17

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29 August 2017

page(s)

4125-4139

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Calmodulin mutations associated with recurrent cardiac arrest in infants

29 August 2017

cites work

1 reference

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Common variation in the NOS1AP gene is associated with drug-induced QT prolongation and ventricular arrhythmia

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Variants in the 3' untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner

16 September 2018

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LQT5 masquerading as LQT2: a dominant negative effect of KCNE1-D85N rare polymorphism on KCNH2 current.

16 September 2018

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16 September 2018

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16 September 2018

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KCNE1 D85N polymorphism--a sex-specific modifier in type 1 long QT syndrome?

16 September 2018

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16 September 2018

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16 September 2018

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Identification of a Kir3.4 mutation in congenital long QT syndrome

16 September 2018

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Polymorphisms in the NOS1AP gene modulate QT interval duration and risk of arrhythmias in the long QT syndrome.

16 September 2018

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Cardiac sodium channelopathies

16 September 2018

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A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project

16 September 2018

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Genotype-phenotype aspects of type 2 long QT syndrome

16 September 2018

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16 September 2018

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NOS1AP is a genetic modifier of the long-QT syndrome

16 September 2018

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Spectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic test

16 September 2018

1 reference

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D85N, a KCNE1 polymorphism, is a disease-causing gene variant in long QT syndrome.

16 September 2018

1 reference

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Fever accentuates transmural dispersion of repolarization and facilitates development of early afterdepolarizations and torsade de pointes under long-QT Conditions

16 September 2018

1 reference

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Common variants at ten loci modulate the QT interval duration in the QTSCD Study

16 September 2018

1 reference

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Common variants at ten loci influence QT interval duration in the QTGEN Study

16 September 2018

1 reference

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Common candidate gene variants are associated with QT interval duration in the general population

16 September 2018

1 reference

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Functional genetic variation of human miRNAs and phenotypic consequences

16 September 2018

1 reference

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Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Age- and genotype-specific triggers for life-threatening arrhythmia in the genotyped long QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Mutation of an A-kinase-anchoring protein causes long-QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Progesterone regulates cardiac repolarization through a nongenomic pathway: an in vitro patch-clamp and computational modeling study

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Diagnostic miscues in congenital long-QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Long QT syndrome and pregnancy

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

N- and C-terminal KCNE1 mutations cause distinct phenotypes of long QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Transient alterations in transmural repolarization gradients and arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Natural selection on human microRNA binding sites inferred from SNP data

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine.

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Antimony-based antileishmanial compounds prolong the cardiac action potential by an increase in cardiac calcium currents

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Phenotypic variability and unusual clinical severity of congenital long-QT syndrome in a founder population

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Nontranscriptional regulation of cardiac repolarization currents by testosterone

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

KCNH2-K897T is a genetic modifier of latent congenital long-QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Identification of a common genetic substrate underlying postpartum cardiac events in congenital long QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Compound mutations: a common cause of severe long-QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

RARE CARDIAC ARRYTHMIAS OF THE PEDIATRIC AGE. II. SYNCOPAL ATTACKS DUE TO PAROXYSMAL VENTRICULAR FIBRILLATION. (PRESENTATION OF 1ST CASE IN ITALIAN PEDIATRIC LITERATURE)

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

A NEW FAMILIAL CARDIAC SYNDROME IN CHILDREN

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Molecular basis of species-specific expression of repolarizing K+ currents in the heart.

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Effect of regression to the mean on decision making in health care

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Epinephrine unmasks latent mutation carriers with LQT1 form of congenital long-QT syndrome.

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Gene-specific response of dynamic ventricular repolarization to sympathetic stimulation in LQT1, LQT2 and LQT3 forms of congenital long QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome.

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Effects of estrogen on action potential and membrane currents in guinea pig ventricular myocytes

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Gender difference in the cycle length-dependent QT and potassium currents in rabbits.

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Normalization of acquired QT prolongation in humans by intravenous potassium.

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

A minK-HERG complex regulates the cardiac potassium current I(Kr)

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Genetically defined therapy of inherited long-QT syndrome. Correction of abnormal repolarization by potassium

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

Role of external Ca2+ and K+ in gating of cardiac delayed rectifier K+ currents

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

The spectrum of symptoms and QT intervals in carriers of the gene for the long-QT syndrome

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779107

A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization

16 September 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.254920

Common Genetic Variation in KCNH2 Is Associated With QT Interval Duration

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.254920

Common Variants in Myocardial Ion Channel Genes Modify the QT Interval in the General Population

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.254920

Neural Control of Heart Rate Is an Arrhythmia Risk Modifier in Long QT Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.254920

How Really Rare Are Rare Diseases?:

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.254920

Genotype-specific onset of arrhythmias in congenital long-QT syndrome: possible therapy implications

21 January 2018

1 reference

12 December 2020

AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Arrhyth

1 reference

12 December 2020

Three generations of hereditary long-QT syndrome with complete penetrance caused by the p.G316E KCNQ1 mutation

1 reference

12 December 2020

Cellular basis for the ECG features of the LQT1 form of the long-QT syndrome: effects of beta-adrenergic agonists and antagonists and sodium channel blockers on transmural dispersion of repolarization and torsade de pointes

1 reference

12 December 2020

Low penetrance in the long-QT syndrome: clinical impact

1 reference

12 December 2020

Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing

1 reference

12 December 2020

Association of KCNQ1, KCNE1, KCNH2 and SCN5A polymorphisms with QTc interval length in a healthy population

1 reference

12 December 2020

Survey of the coding region of the HERG gene in long QT syndrome reveals six novel mutations and an amino acid polymorphism with possible phenotypic effects

1 reference

12 December 2020

Delayed sodium channel inactivation mimics long QT syndrome 3

1 reference

12 December 2020

How really rare are rare diseases?: the intriguing case of independent compound mutations in the long QT syndrome

1 reference

12 December 2020

The time and voltage dependence of the slow outward current in cardiac Purkinje fibres

1 reference

12 December 2020

QTc prolongation measured by standard 12-lead electrocardiography is an independent risk factor for sudden death due to cardiac arrest

1 reference

12 December 2020

10.1113/JPHYSIOL.2013.254920

Identifiers

DOI

1 reference

29 August 2017

0 references

1 reference