(Q38113933)

3 July 2019

5 references

19 September 2019

28 September 2019

2 October 2019

23 November 2020

19 July 2021

Radiolabeled COX-2 inhibitors for non-invasive visualization of COX-2 expression and activity--a critical update (English)

1 reference

3 July 2019

biomedical investigative technique

main subject

1 reference

19 September 2019

1 reference

28 September 2019

1 reference

2 October 2019

1 reference

1 reference

23 November 2020

positron emission tomography

1 reference

23 November 2020

anti-inflammatory agent

1 reference

19 July 2021

3

1 reference

3 July 2019

author name string

Markus Laube

series ordinal

1

1 reference

3 July 2019

Torsten Kniess

series ordinal

2

1 reference

3 July 2019

language of work or name

English

0 references

publication date

29 May 2013

6 references

3 July 2019

19 September 2019

28 September 2019

2 October 2019

23 November 2020

19 July 2021

6 references

3 July 2019

19 September 2019

28 September 2019

2 October 2019

23 November 2020

19 July 2021

18

1 reference

3 July 2019

issue

6

1 reference

3 July 2019

page(s)

6311-6355

1 reference

3 July 2019

Creative Commons Attribution 3.0 Unported

copyright license

5 references

19 September 2019

28 September 2019

2 October 2019

23 November 2020

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

19 July 2021

0 references

1 reference

Imaging of cyclooxygenase-2 (COX-2) expression: potential use in diagnosis and drug evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Cyclooxygenases: structural, cellular, and molecular biology

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

The cyclooxygenase reaction mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Basic biology and clinical application of specific cyclooxygenase-2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Cyclooxygenases: structural and functional insights

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

COX-2 inhibitors act as radiosensitizer in tumor treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Inflammation and cancer: chemical approaches to mechanisms, imaging, and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Expression and translation of the COX-1b gene in human cells--no evidence of generation of COX-1b protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Structural and functional basis of cyclooxygenase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

The COXIB experience: a look in the rearview mirror

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Cyclooxygenase-2 inhibitors: a literature and patent review (2009 - 2010).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Cyclooxygenase-2 expression: a significant prognostic indicator for patients with colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Cyclo-oxygenase 2 expression is associated with angiogenesis and lymph node metastasis in human breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

COX-2 as a target for cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

21 January 2018

Eicosanoids and cancer

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

NSAIDs: Old Drugs Reveal New Anticancer Targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Cyclooxygenase-2 (COX-2) expression is an independent predictor of prostate cancer recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Evaluation of [(11)C]rofecoxib as PET tracer for cyclooxygenase 2 overexpression in rat models of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Synthesis and evaluation in vitro and in vivo of a 11C-labeled cyclooxygenase-2 (COX-2) inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Radiosynthesis of a ¹⁸F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Synthesis of 4-(5-[18F]fluoromethyl-3-phenylisoxazol-4-yl)benzenesulfonamide, a new [18F]fluorinated analogue of valdecoxib, as a potential radiotracer for imaging cyclooxygenase-2 with positron emission tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

¹¹C-labeled analogs of indomethacin esters and amides for brain cyclooxygenase-2 imaging: radiosynthesis, in vitro evaluation and in vivo characteristics in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

In vivo expression of cyclooxygenase-1 in activated microglia and macrophages during neuroinflammation visualized by PET with 11C-ketoprofen methyl ester.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

[¹¹C]diclofenac sodium: synthesis and PET assessment of transdermal penetration.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Synthesis of 18F-labelled cyclooxygenase-2 (COX-2) inhibitors via Stille reaction with 4-[18F]fluoroiodobenzene as radiotracers for positron emission tomography (PET).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

A general method for the synthesis of aryl [11C]methylsulfones: potential PET probes for imaging cyclooxygenase-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Radiosynthesis and evaluation of 11C-labeled diaryl-substituted imidazole and indole derivatives for mapping cyclooxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Synthesis and in vivo evaluation of [18F]-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide as a PET imaging probe for COX-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

General method for the (11)C-labeling of 2-arylpropionic acids and their esters: construction of a PET tracer library for a study of biological events involved in COXs expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Synthesis and preliminary in vitro biological evaluation of new carbon-11-labeled celecoxib derivatives as candidate PET tracers for imaging of COX-2 expression in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Fluorinated COX-2 inhibitors as agents in PET imaging of inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

[I]-Celecoxib Analogues as SPECT Tracers of Cyclooxygenase-2 in Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Radiosynthesis and in vivo evaluation of 11C-labeled 1,5-diarylpyrazole derivatives for mapping cyclooxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Detection of overexpressed COX-2 in precancerous lesions of hamster pancreas and lungs by molecular imaging: implications for early diagnosis and prevention.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Assessment of cyclooxygense-2 expression with 99mTc-labeled celebrex

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Maximal standardized uptake value on FDG-PET is correlated with cyclooxygenase-2 expression in patients with lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

In vivo approaches to quantifying and imaging brain arachidonic and docosahexaenoic acid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

99mTc-diflunisal and the human iris: topical application reveals localization

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Synthesis and structure-activity relationship of a new series of COX-2 selective inhibitors: 1,5-diarylimidazoles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Design, Synthesis, and Biological Evaluation of 6-Substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: A Novel Class of Diarylheterocyclic Selective Cyclooxygenase-2 Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3-phenyl-indoles: a new series of selective COX-2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Can celecoxib affect P-glycoprotein-mediated drug efflux? A microPET study

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Synthesis and evaluation of a radioiodinated lumiracoxib derivative for the imaging of cyclooxygenase-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Site specific chemical delivery of NSAIDs to inflamed joints: synthesis, biological activity and gamma-imaging studies of quaternary ammonium salts of tropinol esters of some NSAIDs or their active metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Cartilage targeted chemical delivery of naproxen and ibuprofen for the treatment of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Triaryl (Z)-olefins suitable for radiolabeling with carbon-11 or fluorine-18 radionuclides for positron emission tomography imaging of cyclooxygenase-2 expression in pathological disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Synthesis and evaluation of fluorobenzoylated di- and tripeptides as inhibitors of cyclooxygenase-2 (COX-2)

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES18066311

Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer

21 January 2018

1 reference

12 December 2020

Radiosynthesis, in vitro validation, and in vivo evaluation of 18F-labeled COX-1 and COX-2 inhibitors.

1 reference

12 December 2020

Synthesis and in vivo evaluation of 18F-desbromo-DuP-697 as a PET tracer for cyclooxygenase-2 expression

1 reference

12 December 2020

Clinical significance of cyclooxygenase-2 (COX-2) in multiple myeloma

1 reference

12 December 2020

Correlations between cyclooxygenase-2 expression and angiogenic factors in primary tumors and liver metastases in colorectal cancer

1 reference

12 December 2020

Expression of cyclooxygenase-2 and transforming growth factor-beta1 in HCV-induced chronic liver disease and hepatocellular carcinoma.

1 reference

12 December 2020

Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): cyclooxygenase (COX) inhibition and beyond

1 reference

12 December 2020

The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes

1 reference

12 December 2020

Efficient sequential synthesis of PET Probes of the COX-2 inhibitor [11C]celecoxib and its major metabolite [11C]SC-62807 and in vivo PET evaluation

1 reference

12 December 2020

Efficient synthesis and chiral separation of 11C-labeled ibuprofen assisted by DMSO for imaging of in vivo behavior of the individual isomers by positron emission tomography

1 reference

12 December 2020

Beyond azide-alkyne click reaction: easy access to 18F-labelled compounds via nitrile oxide cycloadditions

1 reference

12 December 2020

10.3390/MOLECULES18066311

Identifiers

DOI

1 reference

3 July 2019

PMC publication ID

6269837

1 reference

3 July 2019

PubMed publication ID

23760031

1 reference

3 July 2019