(Q38118751)

29 August 2017

Cardiac sodium channelopathy associated with SCN5A mutations: electrophysiological, molecular and genetic aspects (English)

1 reference

29 August 2017

1 reference

Carol Ann Remme

1

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PubMed ID

23818691

29 August 2017

language of work or name

English

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publication date

1 July 2013

1 reference

29 August 2017

18

1 reference

inferred from page(s)

published in

Journal of Physiology

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29 August 2017

591

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29 August 2017

17

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29 August 2017

4099-4116

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Cardiac sodium channel Na(v)1.5 and interacting proteins: Physiology and pathophysiology

29 August 2017

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

14-3-3 is a regulator of the cardiac voltage-gated sodium channel Nav1.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Novel Brugada syndrome-causing mutation in ion-conducting pore of cardiac Na+ channel does not affect ion selectivity properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Brugada syndrome: report of the second consensus conference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

TBX5 drives Scn5a expression to regulate cardiac conduction system function

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Gradient of sodium current across the left ventricular wall of adult rat hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

The cardiac sodium channel: gating function and molecular pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Molecular mechanism for an inherited cardiac arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A)

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Mechanosensitivity of Nav1.5, a voltage-sensitive sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Compound heterozygosity for mutations (W156X and R225W) in SCN5A associated with severe cardiac conduction disturbances and degenerative changes in the conduction system

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A single Na(+) channel mutation causing both long-QT and Brugada syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Atrium-selective sodium channel block as a strategy for suppression of atrial fibrillation: differences in sodium channel inactivation between atria and ventricles and the role of ranolazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Characterization of a novel SCN5A mutation associated with Brugada syndrome reveals involvement of DIIIS4-S5 linker in slow inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Tubulin polymerization modifies cardiac sodium channel expression and gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Intracellular calcium modulation of voltage-gated sodium channels in ventricular myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A novel polyclonal antibody specific for the Na(v)1.5 voltage-gated Na(+) channel 'neonatal' splice form

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Fever-induced life-threatening arrhythmias in children harboring an SCN5A mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Voltage-gated sodium channels are required for heart development in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Non-equilibrium gating in cardiac Na+ channels: an original mechanism of arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Functionally distinct sodium channels in ventricular epicardial and endocardial cells contribute to a greater sensitivity of the epicardium to electrical depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cardiac sodium channel mutation in atrial fibrillation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Molecular basis of ranolazine block of LQT-3 mutant sodium channels: evidence for site of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cardiac histological substrate in patients with clinical phenotype of Brugada syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cardiac sodium channel Nav1.5 is regulated by a multiprotein complex composed of syntrophins and dystrophin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Inherited disorders of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A cardiac sodium channel mutation cosegregates with a rare connexin40 genotype in familial atrial standstill

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Activation of protein kinase C alters the intracellular distribution and mobility of cardiac Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

TGF-β1-mediated fibrosis and ion channel remodeling are key mechanisms in producing the sinus node dysfunction associated with SCN5A deficiency and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Induced pluripotent stem cell derived cardiomyocytes as models for cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Mechanism of right precordial ST-segment elevation in structural heart disease: excitation failure by current-to-load mismatch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A novel disease gene for Brugada syndrome: sarcolemmal membrane-associated protein gene mutations impair intracellular trafficking of hNav1.5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Frequency distribution analysis of activation times and regional fibrosis in murine Scn5a+/- hearts: the effects of ageing and sex

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Extracellular proton modulation of the cardiac voltage-gated sodium channel, Nav1.5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Sodium channel inactivation in heart: a novel role of the carboxy-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

MOG1: a new susceptibility gene for Brugada syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Modulation of Na(v)1.5 by beta1-- and beta3-subunit co-expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Common genetic variation modulating cardiac ECG parameters and susceptibility to sudden cardiac death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Novel SCN5A mutation leading either to isolated cardiac conduction defect or Brugada syndrome in a large French family

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

TGFbeta, cardiac fibroblasts, and the fibrotic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Genetic Na+ channelopathies and sinus node dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Identification of a Conserved Ankyrin-binding Motif in the Family of Sodium Channel α Subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Gain-of-function mutation of Nav1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Subcellular heterogeneity of sodium current properties in adult cardiac ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Diastolic transient inward current in long QT syndrome type 3 is caused by Ca2+ overload and inhibited by ranolazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Reactive oxygen species originating from mitochondria regulate the cardiac sodium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

SCN5A mutation associated with dilated cardiomyopathy, conduction disorder, and arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

SCN5A mutations associate with arrhythmic dilated cardiomyopathy and commonly localize to the voltage-sensing mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A ubiquitous splice variant and a common polymorphism affect heterologous expression of recombinant human SCN5A heart sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cardiomyocytes obtained from induced pluripotent stem cells with long-QT syndrome 3 recapitulate typical disease-specific features in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Characterization of sodium channel alpha- and beta-subunits in rat and mouse cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A mutation in telethonin alters Nav1.5 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Sodium channels as macromolecular complexes: implications for inherited arrhythmia syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Type of SCN5A mutation determines clinical severity and degree of conduction slowing in loss-of-function sodium channelopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Pathophysiological mechanisms of Brugada syndrome: depolarization disorder, repolarization disorder, or more?

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Dynamic reciprocity of sodium and potassium channel expression in a macromolecular complex controls cardiac excitability and arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Regulated and aberrant glycosylation modulate cardiac electrical signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Ranolazine shortens repolarization in patients with sustained inward sodium current due to type-3 long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

The Na+ channel inactivation gate is a molecular complex: a novel role of the COOH-terminal domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Developmentally regulated SCN5A splice variant potentiates dysfunction of a novel mutation associated with severe fetal arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Functional effects of protein kinase C activation on the human cardiac Na+ channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Divergent biophysical defects caused by mutant sodium channels in dilated cardiomyopathy with arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Sodium channel mutations and susceptibility to heart failure and atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

SCN5A mutations and the role of genetic background in the pathophysiology of Brugada syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Sodium channel (dys)function and cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Late sodium current inhibition in acquired and inherited ventricular (dys)function and arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cardiac sodium channel overlap syndromes: different faces of SCN5A mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Intercalated disc abnormalities, reduced Na(+) current density, and conduction slowing in desmoglein-2 mutant mice prior to cardiomyopathic changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Biology of cardiac sodium channel Nav1.5 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Novel pore mutation in SCN5A manifests as a spectrum of phenotypes ranging from atrial flutter, conduction disease, and Brugada syndrome to sudden cardiac death

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Mouse model of SCN5A-linked hereditary Lenègre's disease: age-related conduction slowing and myocardial fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Loss of plakophilin-2 expression leads to decreased sodium current and slower conduction velocity in cultured cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cardiac conduction defects associate with mutations in SCN5A

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Structure and function of splice variants of the cardiac voltage-gated sodium channel Na(v)1.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

The congenital long QT syndromes from genotype to phenotype: clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Human heart failure is associated with abnormal C-terminal splicing variants in the cardiac sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cardiac sodium channel NaV1.5 distribution in myocytes via interacting proteins: the multiple pool model

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A cardiac sodium channel mutation identified in Brugada syndrome associated with atrial standstill

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Partial expression defect for the SCN5A missense mutation G1406R depends on splice variant background Q1077 and rescue by mexiletine

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Genetic control of sodium channel function

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Delay in right ventricular activation contributes to Brugada syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Transforming growth factor beta (TGF-beta) signaling is regulated by electrical activity in skeletal muscle cells. TGF-beta type I receptor is transcriptionally regulated by myotube excitability

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Loss-of-function mutation of the SCN3B-encoded sodium channel {beta}3 subunit associated with a case of idiopathic ventricular fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Possible bradycardic mode of death and successful pacemaker treatment in a large family with features of long QT syndrome type 3 and Brugada syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Contribution of sodium channel mutations to bradycardia and sinus node dysfunction in LQT3 families

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Effects of heart failure on brain-type Na+ channels in rabbit ventricular myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Inherited sodium channelopathies: a continuum of channel dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Mutations in sodium channel β1- and β2-subunits associated with atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

De novo mutation in the SCN5A gene associated with early onset of sudden infant death

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Inherited conduction system abnormalities--one group of diseases, many genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

alpha-1-syntrophin mutation and the long-QT syndrome: a disease of sodium channel disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Localization of cardiac sodium channels in caveolin-rich membrane domains: regulation of sodium current amplitude

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Localization of Na+ channel isoforms at the atrioventricular junction and atrioventricular node in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Glycosylation influences voltage-dependent gating of cardiac and skeletal muscle sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

LQTS mutation N1325S in cardiac sodium channel gene SCN5A causes cardiomyocyte apoptosis, cardiac fibrosis and contractile dysfunction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.256461

SCN1Bb R214Q found in 3 patients: 1 with Brugada syndrome and 2 with lone atrial fibrillation

21 January 2018

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The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility

21 January 2018

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A ZASP missense mutation, S196L, leads to cytoskeletal and electrical abnormalities in a mouse model of cardiomyopathy

5 November 2018

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Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans

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12 December 2020

Membrane-select regulation of cardiac Na(v) channel isoforms

1 reference

12 December 2020

Dilated cardiomyopathy due to sodium channel dysfunction: what is the connection?

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12 December 2020

Cardiac disturbances during the administration of taxol

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12 December 2020

Quantitative trait loci for electrocardiographic parameters and arrhythmia in the mouse

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12 December 2020

Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes

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12 December 2020

Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel

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12 December 2020

Homozygous mutation in SCN5A associated with atrial quiescence, recalcitrant arrhythmias, and poor capture thresholds

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12 December 2020

Heterogeneity of sodium current in atrial vs epicardial ventricular myocytes of adult guinea pig hearts

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12 December 2020

Haploinsufficiency in combination with aging causes SCN5A-linked hereditary Lenègre disease

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12 December 2020

Altered atrial, atrioventricular, and ventricular conduction in patients with the long QT syndrome caused by the DeltaKPQ SCN5A sodium channel gene mutation

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Identifiers

DOI

1 reference

29 August 2017

0 references

1 reference

PubMed ID

23818691