(Q38121170)

29 August 2017

title

Diversification of NAD biological role: the importance of location (English)

1 reference

29 August 2017

Michele Di Stefano

1

1 reference

29 August 2017

Laura Conforti

series ordinal

2

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29 August 2017

language of work or name

English

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publication date

1 August 2013

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29 August 2017

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29 August 2017

volume

280

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29 August 2017

issue

19

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29 August 2017

page(s)

4711-4728

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The new life of a centenarian: signalling functions of NAD(P).

29 August 2017

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Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus

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Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreas

21 January 2018

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Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2

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CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy

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NAD(P) biosynthesis enzymes as potential targets for selective drug design

21 January 2018

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Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases

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Functional aspects of protein mono-ADP-ribosylation

21 January 2018

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The world according to PARP.

21 January 2018

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The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases.

21 January 2018

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Sirtuin chemical mechanisms

21 January 2018

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Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

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Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes

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The biochemistry of sirtuins.

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Function and metabolism of sirtuin metabolite O-acetyl-ADP-ribose

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Release, neuronal effects and removal of extracellular β-nicotinamide adenine dinucleotide (β-NAD⁺) in the rat brain

21 January 2018

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High sensitivity of CD4+CD25+ regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: a role for P2X7 receptors

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Extracellular NAD+ regulates intracellular free calcium concentration in human monocytes

21 January 2018

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P2X7 receptor-dependent and -independent T cell death is induced by nicotinamide adenine dinucleotide

21 January 2018

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21 January 2018

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Biochemistry, localization and functional roles of ecto-nucleotidases in the nervous system

21 January 2018

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Ectonucleotidases as regulators of purinergic signaling in thrombosis, inflammation, and immunity

21 January 2018

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CD157, the Janus of CD38 but with a unique personality

21 January 2018

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Human CD38 is associated to distinct molecules which mediate transmembrane signaling in different lineages

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Physiological relevance of the endogenous mono(ADP-ribosyl)ation of cellular proteins

21 January 2018

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Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling

21 January 2018

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Purification and properties of a mouse liver plasma-membrane glycoprotein hydrolysing nucleotide pyrophosphate and phosphodiester bonds

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

ADP ribose is an endogenous ligand for the purinergic P2Y1 receptor.

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Suppression of PC-1/ENPP-1 expression improves insulin sensitivity in vitro and in vivo

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Evidence that inhibition of insulin receptor signaling activity by PC-1/ENPP1 is dependent on its enzyme activity

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Review: NAD +: a modulator of immune functions

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Pre-B cell colony-enhancing factor (PBEF)/visfatin: a novel mediator of innate immunity

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Nicotinamide phosphoribosyltransferase (Nampt): a link between NAD biology, metabolism, and diseases

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism.

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity

21 January 2018

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RETRACTED: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin

21 January 2018

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Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Pre-B cell colony enhancing factor (PBEF)/visfatin induces secretion of MCP-1 in human endothelial cells: role in visfatin-induced angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1

21 January 2018

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Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Exome sequencing identifies NMNAT1 mutations as a cause of Leber congenital amaurosis

21 January 2018

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NMNAT1 mutations cause Leber congenital amaurosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Mutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degeneration

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Mutations in NMNAT1 cause Leber congenital amaurosis with early-onset severe macular and optic atrophy

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

21 January 2018

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Advances in using PARP inhibitors to treat cancer

21 January 2018

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Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Poly(ADP-ribose) polymerase: killer or conspirator? The 'suicide hypothesis' revisited

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation

21 January 2018

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A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.

21 January 2018

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Mediation of cell death by poly(ADP-ribose) polymerase-1.

21 January 2018

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NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death

21 January 2018

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Advances in characterization of human sirtuin isoforms: chemistries, targets and therapeutic applications.

21 January 2018

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Calorie restriction--the SIR2 connection

21 January 2018

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Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

21 January 2018

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Sir2: an NAD-dependent histone deacetylase that connects chromatin silencing, metabolism, and aging

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

SirT1 regulates energy metabolism and response to caloric restriction in mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

SIRT1, metabolism and cancer

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Acetylation of tau inhibits its degradation and contributes to tauopathy

21 January 2018

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Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

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SIRT1 regulates circadian clock gene expression through PER2 deacetylation

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

21 January 2018

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Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis

21 January 2018

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Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

21 January 2018

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Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding

21 January 2018

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Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation

21 January 2018

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Nutrient sensing and the circadian clock

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Molecular identification and functional characterization of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Identification of the mitochondrial NAD+ transporter in Saccharomyces cerevisiae

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Acetylation of mitochondrial proteins

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

21 January 2018

Mitochondrial sirtuins

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https://api.crossref.org/works/10.1111%2FFEBS.12433

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Identification of ADP-ribosylation site in human glutamate dehydrogenase isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Poly(ADP-ribose) polymerase facilitates the repair of N-methylpurines in mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Intra-mitochondrial poly(ADP-ribosyl)ation: potential role for alpha-ketoglutarate dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Ca(2+)-induced Ca2+ release in sea urchin egg homogenates: modulation by cyclic ADP-ribose

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-ribose

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Calcium signaling by cyclic ADP-ribose, NAADP, and inositol trisphosphate are involved in distinct functions in ascidian oocytes

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Mitochondrial dysfunction and nicotinamide dinucleotide catabolism as mechanisms of cell death and promising targets for neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Subcellular localization determines the stability and axon protective capacity of axon survival factor Nmnat2.

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Degeneration and regeneration of the peripheral nervous system: from Augustus Waller's observations to neuroinflammation

21 January 2018

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An 85-kb tandem triplication in the slow Wallerian degeneration (Wlds) mouse

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Targeting NMNAT1 to axons and synapses transforms its neuroprotective potency in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.12433

Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

NAD(+) and axon degeneration revisited: Nmnat1 cannot substitute for Wld(S) to delay Wallerian degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

A local mechanism mediates NAD-dependent protection of axon degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

NMNAT expression and its relation to NAD metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Fasting promotes the expression of SIRT1, an NAD+ -dependent protein deacetylase, via activation of PPARalpha in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

Regulation of Human Mesenchymal Stem Cell Functions by an Autocrine Loop Involving NAD+ Release and P2Y11-Mediated Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12433

21 January 2018

Identifiers

DOI

10.1111/FEBS.12433

1 reference

29 August 2017

1 reference