(Q38121824)

29 August 2017

title

Chemistry and formulations for siRNA therapeutics (English)

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29 August 2017

Andrzej Gallas

1

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29 August 2017

Cameron Alexander

2

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29 August 2017

Martyn C Davies

3

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29 August 2017

Sanyogitta Puri

4

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29 August 2017

Stephanie Allen

5

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29 August 2017

publication date

1 October 2013

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29 August 2017

published in

Chemical Society Reviews

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29 August 2017

volume

42

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29 August 2017

issue

20

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29 August 2017

page(s)

7983-7997

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Knocking down barriers: advances in siRNA delivery

29 August 2017

cites work

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol

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Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

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21 January 2018

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21 January 2018

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21 January 2018

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Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes

21 January 2018

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The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.

21 January 2018

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Rational design of targeted cancer therapeutics through the multiconjugation of folate and cleavable siRNA to RAFT-synthesized (HPMA-s-APMA) copolymers

21 January 2018

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Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells.

21 January 2018

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21 January 2018

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A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium

21 January 2018

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21 January 2018

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21 January 2018

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Asymmetric RNA duplexes mediate RNA interference in mammalian cells.

21 January 2018

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Rational design of cationic lipids for siRNA delivery

21 January 2018

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Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

21 January 2018

1 reference

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Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo.

21 January 2018

1 reference

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High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization

21 January 2018

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Therapeutic plasmid DNA versus siRNA delivery: common and different tasks for synthetic carriers

21 January 2018

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Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

21 January 2018

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A phenylboronate-functionalized polyion complex micelle for ATP-triggered release of siRNA.

21 January 2018

1 reference

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SiRNA delivery with exosome nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CS35520A

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

21 January 2018

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Intelligent nucleic acid delivery systems based on stimuli-responsive polymers

21 January 2018

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21 January 2018

Identifiers

DOI

10.1039/C3CS35520A

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29 August 2017

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