(Q38125500)

29 August 2017

Targeting cancer stem cells with sulforaphane, a dietary component from broccoli and broccoli sprouts (English)

1 reference

29 August 2017

neoplastic stem cells

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Yanyan Li

1

1 reference

PubMed ID

23902242

29 August 2017

Tao Zhang

series ordinal

2

1 reference

PubMed ID

23902242

29 August 2017

language of work or name

English

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publication date

1 August 2013

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29 August 2017

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29 August 2017

9

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29 August 2017

8

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29 August 2017

1097-1103

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Multi-targeted prevention of cancer by sulforaphane

29 August 2017

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

The chemical diversity and distribution of glucosinolates and isothiocyanates among plants

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Epithiospecifier protein from broccoli (Brassica oleracea L. ssp. italica) inhibits formation of the anticancer agent sulforaphane

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Protection of humans by plant glucosinolates: efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Sulforaphane induces caspase-mediated apoptosis in cultured PC-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Is tumor growth sustained by rare cancer stem cells or dominant clones?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Breast tumor heterogeneity: cancer stem cells or clonal evolution?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Prospective identification of tumorigenic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Identification of pancreatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Identification of cells initiating human melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Significance of CD90+ cancer stem cells in human liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Mammary stem cells, self-renewal pathways, and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Stem cells, cancer, and cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Tumour-initiating cells: challenges and opportunities for anticancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Radiation resistance and stem-like cells in brain tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Cancer stem cells: current status and evolving complexities

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

The hedgehog signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Emerging role of Notch in stem cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Notch signaling: from the outside in

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

The Notch signaling pathway: transcriptional regulation at Notch target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Modulatory properties of various natural chemopreventive agents on the activation of NF-kappaB signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

NF-kappaB: linking inflammation and immunity to cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Immunity, Inflammation, and Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Nuclear factor-kappaB contributes to hedgehog signaling pathway activation through sonic hedgehog induction in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Characterization of sonic hedgehog as a novel NF-kappaB target gene that promotes NF-kappaB-mediated apoptosis resistance and tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Sonic hedgehog signaling inhibition provides opportunities for targeted therapy by sulforaphane in regulating pancreatic cancer stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Epithelial-mesenchymal transition in cancer development and its clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2, 9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Antiproliferative activity of sulforaphane in Akt-overexpressing ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

21 January 2018

The renaissance of GSK3

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Sulforaphane increases drug-mediated cytotoxicity toward cancer stem-like cells of pancreas and prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Sulforaphane potentiates the efficacy of imatinib against chronic leukemia cancer stem cells through enhanced abrogation of Wnt/β-catenin function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.13.108

21 January 2018

Identifiers

DOI

10.2217/FON.13.108

1 reference

29 August 2017

1 reference

PubMed ID

23902242